DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and Adcy10

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_766617.2	Gene:	Adcy10 / 271639	MGIID:	2660854	Length:	1614	Species:	Mus musculus

Alignment Length:	155	Identity:	33/155 - (21%)
Similarity:	58/155 - (37%)	Gaps:	35/155 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 DGIIKQCAQVI-FGPVCDYSLAAVSRITKYFNSQ--GTPLISVGGSTYDFEQKKTDCNDEFY--M 163
            |.::..|::|: :..:..|..:.|....:|..||  ....:::..:...|.|       .||  .
Mouse   502 DFLMTNCSRVLMYEGLPGYGKSQVLMEIEYLASQHENHRAVAIALTKISFHQ-------NFYTIQ 559

  Fly   164 LLRTGMLSFET---ISELTINVMKR---------HNWSHSIFYYERDGQRSVAGMHTC------- 209
            :|...:|..:|   ..|...|:..|         |...:.||:.:....|.::.|...
Mouse   560 ILMANVLGLDTCKHYKERQTNLQNRVKTLLDEKFHCLLNDIFHVQFPVSREMSRMSKIRKQKQLE 624

  Fly   210 FLMMKSLGKQMRNENMTF----AQF 230
            .|.||.|.:.:|.|.:.|    |||
Mouse   625 ALFMKILAQTVREERIIFIIDEAQF 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	33/155 (21%)
Adcy10	NP_766617.2	CHD	40..214	CDD:143636
		CHD	292..461	CDD:143636
		COG3899	485..>959	CDD:226415	33/155 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900