DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14877 and Gucy1b2

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_011243363.2	Gene:	Gucy1b2 / 239134	MGIID:	2660873	Length:	829	Species:	Mus musculus

Alignment Length:	248	Identity:	47/248 - (18%)
Similarity:	82/248 - (33%)	Gaps:	86/248 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ICDA-NGRNCTIRALVLL---PDDNMYQASLPRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTK 92
            :|.. ...:..:||.|||   |..:.:|...|..|.|    |:::...: .|.|:.|:......:
Mouse   341 VCPGEKSHSAVVRASVLLGKGPLGDTFQPVFPERLWI----EEEVFCNA-FPFHVVFDEALRVKQ 400

  Fly    93 CDASLGVIKAMDGIIKQ-----------CAQVIFGPVCDYSLAAVSRITKYFNSQGTPLISVGGS 146
              |.:.:.|.:.||:.|           ..||.|.         :|.|.|:.|||
Mouse   401 --AGVNIQKYVPGILTQKFGLDEYFSIVHPQVTFN---------ISSICKFINSQ---------- 444

  Fly   147 TYDFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWSHSIFYYERDGQRSVAGMHTCFL 211
                          |.:..|..|:.....|:.|:.:..:..|..|:        :.:..|  |..
Mouse   445 --------------FILKTRREMMPEAWKSQPTLKLRGQMIWMESL--------KCMVFM--CSP 485

  Fly   212 MMKSLGKQMRNENM--------------------TFAQFPLEPNLTNRTEEMR 244
            .::|| :::....|                    ..|:..|...|..:.||:|
Mouse   486 KLRSL-QELEESKMHLSDIAPHDTTRDLILLNQQRLAEMELSCQLEKKKEELR 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	41/228 (18%)
Gucy1b2	XP_011243363.2	HNOB	115..276	CDD:400167
		HNOBA	380..566	CDD:400168	35/205 (17%)
		Guanylate_cyc	572..754	CDD:306677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900