DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gcy-36

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_510557.3	Gene:	gcy-36 / 191657	WormBaseID:	WBGene00001556	Length:	675	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	39/187 - (20%)
Similarity:	62/187 - (33%)	Gaps:	58/187 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 PDDNM---YQASLPRVLPILK-----VAEQ------------------QIRSKSLIPSHIDF--E 85
            ||..:   |....|.:.||:|     .|::                  |:.:...|..|:.|  :
Worm   128 PDGTITLHYYTGRPGLYPIVKGVLREAAKRVFKLDVSMTITGRTQRSVQMATGERIEEHVIFLVK 192

  Fly    86 WLAHDTKCDASLGV------------IKAMDGIIKQCAQVIFGPVCDYSLAAVSR-----ITKYF 133
            .|..|...:.:||.            :..||.|......::....|  .:..|.|     |.|..
Worm   193 TLNTDQSNEEALGTAVVQHSNNYKIRLTHMDFISTFPYHMVVDQDC--KIVQVGRELYNHIPKDL 255

  Fly   134 NSQGTPLISVGGST-----YDFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKR 185
            .|.||||:.:...|     .||:......|..|.:.::|..:.|:.      |..||
Worm   256 LSVGTPLMRIFEVTRPQIPLDFDSICNFINAVFVLQVKTTPMEFQR------NANKR 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	39/187 (21%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:285002	8/38 (21%)
		HNOBA	217..435	CDD:285003	23/98 (23%)
		CYCc	415..604	CDD:214485
		Guanylate_cyc	441..624	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900