DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gcy-5

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_496219.1	Gene:	gcy-5 / 191643	WormBaseID:	WBGene00001532	Length:	1122	Species:	Caenorhabditis elegans

Alignment Length:	180	Identity:	39/180 - (21%)
Similarity:	75/180 - (41%)	Gaps:	21/180 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ARDCEAICDANGRNCTIRALVLLPDD----NMYQASLPRVLPILKVAEQQIRSKSLIPSHIDFEW 86
            |.:|:.|..:..   |:|..:....|    ::..||....|||   |.|.::||..: :..|.|:
Worm    16 ASECQVIPSSRR---TLRVGIAAAQDTQSGSIGWASCGGTLPI---AVQYLKSKGFL-TDFDVEY 73

  Fly    87 LAHDTKCDASLGVIKAMDGIIKQC-AQVIFGPVCDYSLAAVSRITKYFNSQGTPLISVGGSTYDF 150
            ....|:||.: .|.||....:|:. ..|:.||.|..:||.:..::..:..    |:...|...|.
Worm    74 YMEYTECDRA-SVAKAGMKFMKEMNVDVVVGPSCGDALAIMGTLSAIYKK----LVLGWGFVSDT 133

  Fly   151 EQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWSHSIFYYERDGQ 200
            :...|:    .:..:.:...:.:|:...|..:::...:......|.:|.|
Worm   134 QLADTN----RFPYVASVQPTAQTLGLATSRILEMFQFDRVALLYYKDDQ 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	34/160 (21%)
gcy-5	NP_496219.1	PBP1_NPR_GC_like	30..440	CDD:107347	35/163 (21%)
		ANF_receptor	49..426	CDD:279440	31/144 (22%)
		PK_GC	546..816	CDD:270894
		HNOBA	<830..873	CDD:285003
		CYCc	852..1042	CDD:214485
		Guanylate_cyc	879..1067	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810