DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gcy-3

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_496037.1	Gene:	gcy-3 / 191641	WormBaseID:	WBGene00001530	Length:	1140	Species:	Caenorhabditis elegans

Alignment Length:	162	Identity:	32/162 - (19%)
Similarity:	68/162 - (41%)	Gaps:	36/162 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 PILKV---AEQQIRSKSL--------IP------------SHIDFEWLAHDTKCDASLGVIKAMD 104
            |.|||   |.|:.:|.|:        :|            ::.|||:....|:||.:..|...::
Worm    33 PKLKVGIAAAQKTQSASIGWNVCGGAVPLAIERLKQAGYVTNFDFEYYVEYTECDLASTVRTGIN 97

  Fly   105 GIIKQCAQVIFGPVCDYSLAAVSRITKYFNSQGTPLISVGGSTYDFEQKKTDCND--EFYMLLRT 167
            .:......||.||.|..::..::.:...:..   |::..|..:      :.|.:|  .|..|: |
Worm    98 FLKNLEVDVIIGPPCSEAIRTMATLATLYKK---PVLGWGFVS------QADLSDMTRFPYLI-T 152

  Fly   168 GMLSFETISELTINVMKRHNWSH-SIFYYERD 198
            .:.:.:|:......:::.:.|.. ::.||:.:
Worm   153 VLPTSQTLGYAASKLLELYKWDKVALLYYKSE 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	32/162 (20%)
gcy-3	NP_496037.1	PBP1_NPR_GC_like	36..453	CDD:107347	30/159 (19%)
		ANF_receptor	54..433	CDD:279440	24/141 (17%)
		PKc_like	554..823	CDD:304357
		HNOBA	<839..882	CDD:285003
		CYCc	861..1051	CDD:214485
		Guanylate_cyc	888..1076	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900