DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gcy-7

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001360539.1	Gene:	gcy-7 / 179222	WormBaseID:	WBGene00001534	Length:	1117	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	38/161 - (23%)
Similarity:	65/161 - (40%)	Gaps:	30/161 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VAEQQIRSKSLIPSHIDFEWLAHDTKCDASLGVIKAMDGIIKQCAQVIFGPVCDYSLAAVSRITK 131
            :|..:::.::|: |..:|.:......|..|......:|.|.|....||.||..:....|...::.
Worm    63 IAVDRLKRENLM-SGWEFNFTIEFDDCVESEAAGMTVDLIEKHNVDVIIGPTMNQPTLAAFIVSN 126

  Fly   132 YFNSQGTPLISVGGSTYDFEQKKTDCNDEFYMLLRTGMLSF--ETISELTINVMKRHNWSHSIFY 194
            |||   .|:|:.|  ..:..|.     |:|......|:||.  .::......|:||:.||..::.
Worm   127 YFN---RPIIAWG--LVNAAQL-----DDFERFPNAGILSAGQRSLGVAIRAVLKRYEWSQFVYA 181

  Fly   195 Y--ERDGQRSVAGMHTCFLMMKSLGKQMRNE 223
            |  |.|.::.|.               |||:
Worm   182 YFTEEDTEKCVT---------------MRND 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	38/161 (24%)
gcy-7	NP_001360539.1	PBP1_NPR_GC-like	36..438	CDD:380575	38/161 (24%)
		PKc_like	550..822	CDD:389743
		CYCc	860..1049	CDD:214485
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910