DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gcy-18

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_502449.2	Gene:	gcy-18 / 178237	WormBaseID:	WBGene00001543	Length:	1113	Species:	Caenorhabditis elegans

Alignment Length:	150	Identity:	33/150 - (22%)
Similarity:	65/150 - (43%)	Gaps:	24/150 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IRALVLLPDDNMYQASLPRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTKCDASLGVIKAMDGI 106
            |.|:.::|:|          ..||.::::.:..:.|:...|:||.::.....::..||..|.:..
Worm    58 IGAVGVMPND----------ARILNISKENLIEEGLVGDDIEFEIVSRQACSESFEGVAVAAELY 112

  Fly   107 IKQCAQVIFGPVCDYSLAAVSRITKYFNSQGTPLI---SVGGSTYDFEQKKTDCNDEFYMLLRTG 168
            .....:...||.|...|.||:::..::|   .|:|   ||..:..|....||        |.|..
Worm   113 HVHQVRAFIGPYCAAELEAVTKMATFWN---IPIISYSSVPNAVSDRSVYKT--------LARVS 166

  Fly   169 MLSFETISELTINVMKRHNW 188
            ..:..:|:|.|:.::..:.|
Worm   167 SKNTNSIAEATVALLLHYKW 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	30/145 (21%)
gcy-18	NP_502449.2	Periplasmic_Binding_Protein_Type_1	87..448	CDD:299141	25/110 (23%)
		ANF_receptor	87..395	CDD:279440	25/110 (23%)
		PKc_like	549..846	CDD:304357
		HNOBA	<857..903	CDD:285003
		CYCc	882..1073	CDD:214485
		Guanylate_cyc	909..1095	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810