DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and acy-3

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_497765.4	Gene:	acy-3 / 175489	WormBaseID:	WBGene00000070	Length:	1243	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	44/188 - (23%)
Similarity:	72/188 - (38%)	Gaps:	54/188 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VLLLVGLVFGPKDCVATC---------REEPARDCEAICDANGRNCT------IRALVLLPDDNM 53
            |.:..|.:.|.:..:|.|         :|..:| .|.:..:||  ||      |.|:..:|..:.
Worm   229 VSVAYGRLVGFESVLAQCSSIDAARVLKELDSR-IERLAASNG--CTRVASEGITAVCSIPGIDS 290

  Fly    54 YQASLPRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTKCDASL-----------GVIKAMDGII 107
            ..|:        |:....:..::||.|..|      .|..|.|:           ||:    |:.
Worm   291 QHAT--------KLCRFSMELETLINSFRD------ATGADVSVCIGIDSGPVTAGVV----GVS 337

  Fly   108 KQCAQVIFGPVCDYSLAAVSRITK---YFNSQGTPLISVGGSTYDFEQKKTDCNDEFY 162
            |....|| |.|.|.:|...|..|:   |.:::....:   |||.:||.:|.....:.|
Worm   338 KWHYDVI-GSVFDNALLMQSNATEPGVYVSNETRRFL---GSTGEFELEKCPIGWKLY 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	30/131 (23%)
acy-3	NP_497765.4	TctB	26..137	CDD:284693
		CYCc	195..378	CDD:214485	40/173 (23%)
		Nucleotidyl_cyc_III	221..382	CDD:299850	42/177 (24%)
		CYCc	696..873	CDD:214485
		Nucleotidyl_cyc_III	711..880	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900