DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and Gucy2e

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_036012232.1	Gene:	Gucy2e / 14919	MGIID:	105123	Length:	1139	Species:	Mus musculus

Alignment Length:	295	Identity:	63/295 - (21%)
Similarity:	103/295 - (34%)	Gaps:	93/295 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VLLLVGLVFGPKDCVATCREEPARDCEAICDANGRNCTIRAL-VLLPD-----DNMYQASLPRVL 62
            |.|.:||.      :|...:.||...|.|......:|...:| .||..     |.|:::||  :|
Mouse   626 VALYLGLF------LAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSL--LL 682

  Fly    63 PILK---------VAEQQIRSKSLI---------------------------PSHIDFEWLAHDT 91
            .::|         ||..:::|::.:                           ||..|..|.|.:.
Mouse   683 DLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPEL 747

  Fly    92 KCDASLGVIKAMDGIIKQCAQVIFGPVCDYSLAAVSRITKYFNSQGT--------PLISVGGSTY 148
            ..|.||.....:.|.:...|.::...||..:..|:..:|.....|..        ||:|:..:..
Mouse   748 LRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPM 812

  Fly   149 DFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWSHSIFYYERDGQRSVAGMHTCFL-- 211
            :..|..|.|..| :..||..|       :||.::.|..|                .|..|..:
Mouse   813 ECIQLMTQCWAE-HPELRPSM-------DLTFDLFKSIN----------------KGRKTNIIDS 853

  Fly   212 MMKSLGKQMRNENMTFAQFPLEPNLTNRTEEMRRE 246
            |::.|.:...|         ||..:..||||:.:|
Mouse   854 MLRMLEQYSSN---------LEDLIRERTEELEQE 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	48/245 (20%)
Gucy2e	XP_036012232.1	PBP1_sensory_GC_DEF-like	58..465	CDD:380594
		PK_GC-2D	570..845	CDD:270945	51/250 (20%)
		HNOBA	<854..899	CDD:400168	10/35 (29%)
		CYCc	879..1070	CDD:214485	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900