DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and Npr2

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_446290.1	Gene:	Npr2 / 116564	RGDID:	620851	Length:	1047	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	63/313 - (20%)
Similarity:	109/313 - (34%)	Gaps:	99/313 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLVLLLVGLVFGPKDCVATCREEPARDCEAICDANGRNCTIRALVLLPDDNM-YQASLPRVLPI 64
            :|:|..|.|.|..|                     ..||.|:  .|:||:.|: |..:.|||.|.
  Rat     7 LLVVAALAGGVRPP---------------------GARNLTL--AVVLPEHNLSYAWAWPRVGPA 48

  Fly    65 LKVAEQQIRSKSLIPSHIDFEWLAHDTKCDASLGVIKAMDGIIKQCAQVIFGPVCDYSLAAVSRI 129
            :.:|.:.:  ...:|..:.|.....|..|...|..::|:|..:.....::.||.|.|..|:|:|.
  Rat    49 VALAVEAL--GRALPVDLRFVSSELDGACSEYLAPLRAVDLKLYHDPDLLLGPGCVYPAASVARF 111

  Fly   130 TKYFNSQGTPLISVGGSTYDFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWS----- 189
            ..:::   .||::.|.....|..|    |:.:..|:|||. |...:.|..:.:....||:
  Rat   112 ASHWH---LPLLTAGAVASGFAAK----NEHYRTLVRTGP-SAPKLGEFVVTLHGHFNWTARAAL 168

  Fly   190 -------------------------------HSIFYYERDGQRSVAG--------MHTC--FLMM 213
                                           |.::..|..|......        ::.|  ..|:
  Rat   169 LYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYTREPGGPEQATHFIRANGRIVYICGPLEML 233

  Fly   214 KSLGKQMRNENMT---FAQFPLE----------------PNLTNRTEEMRREI 247
            ..:..|.:.||:|   :..|.|:                |...|||:|..:.:
  Rat   234 HEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTQEQAQAL 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	52/260 (20%)
Npr2	NP_446290.1	PBP1_NPR_B	26..421	CDD:380607	55/273 (20%)
		PK_GC-A_B	518..792	CDD:270944
		HNOBA	<798..846	CDD:400168
		CYCc	825..1009	CDD:214485
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810