DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and Adcy6

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_006520366.3	Gene:	Adcy6 / 11512	MGIID:	87917	Length:	1254	Species:	Mus musculus

Alignment Length:	161	Identity:	31/161 - (19%)
Similarity:	53/161 - (32%)	Gaps:	62/161 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LVLLLVG----------LVFGPKDCVATCREEPARDCEAICDANGRNCTIRALVLLPDDNMYQAS 57
            |||||:|          |:.|.....::.......||.|:    ||       |.|      :..
Mouse   936 LVLLLLGPPAAIFDNYDLLLGVHGLASSNETFDGLDCPAV----GR-------VAL------KYM 983

  Fly    58 LPRVLPILKVA----EQQIRSKSLIPSHIDFEWLAHDTKCDASLGVIKA-----MDGIIK----- 108
            .|.:|.:..:|    .||:.|    .:.:||.|....|.....:..::|     :..|:.
Mouse   984 TPVILLVFALALYLHAQQVES----TARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAA 1044

  Fly   109 -----------------QCAQVIFGPVCDYS 122
                             :|..|:|..:.::|
Mouse  1045 HFLARERRNDELYYQSCECVAVMFASIANFS 1075

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	18/108 (17%)
Adcy6	XP_006520366.3	AC_N	83..454	CDD:318454
		Guanylate_cyc	456..640	CDD:306677
		DUF1053	668..754	CDD:368844
		Guanylate_cyc	1056..1250	CDD:306677	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900