Protein Alignment CG14877 and ADCY3

DIOPT Version :9

• Sequence 1: NP_650507.1
• Gene: CG14877 / 41929
• FlyBaseID: FBgn0038380
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: XP_011530791.1
• Gene: ADCY3 / 109
• HGNCID: 234
• Length: 1186
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 35/214 - (16%)
• Similarity: 77/214 - (35%)
• Gaps: 61/214 - (28%)

  Fly    78 IPSHIDFEWLAHDTKCDASLGVIKAMDGIIKQCAQVIFGPVCDYSLAAVSRI----TKYFNSQG- 137
            :|:..||  ...::..:..:..::.::.||.....::..|    ....:::|    :.|..:.|
Human   971 LPNFADF--YTEESINNGGIECLRFLNEIISDFDSLLDNP----KFRVITKIKTIGSTYMAASGV 1029

  Fly   138 TPLISVGGSTYDFEQKK-----------------------TDCNDEFY--MLLRTGMLSFETISE 177
            ||.::..|.....::.|                       |:.|::.:  .:||.||.....::.
Human  1030 TPDVNTNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 1094

  Fly   178 LTINVMKRHN--WSHSIFYYERDGQRSVAG----MHTCFLMMKSLGKQM----------RNENMT 226
            : |...|.|.  |.:::....|.....|.|    :....::::..|.:.          :.|.:|
Human  1095 V-IGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLT 1158

  Fly   227 F--------AQFPLEPNLT 237
            |        |.||..|::|
Human  1159 FFLKGRDKLATFPNGPSVT 1177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	35/214 (16%)
ADCY3	XP_011530791.1	AC_N	<44..303	CDD:292831
		CYCc	273..490	CDD:214485
		Guanylate_cyc	310..516	CDD:278633
		CYCc	925..1143	CDD:214485	27/178 (15%)
		Guanylate_cyc	956..1163	CDD:278633	30/198 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900