DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and npr3

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_004910476.1	Gene:	npr3 / 100495974	XenbaseID:	XB-GENE-1012470	Length:	508	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	64/253 - (25%)
Similarity:	115/253 - (45%)	Gaps:	37/253 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLVLLLVGLVFGPKDCVATCREEPARDCEAICDANGRNCTIRALVLLPDDNMYQASLPRVLPIL 65
            :||:.|:|.||.       ..:..|..:           .|:..|||||.||.|..|:.||.|.:
Frog     4 ILLLSLMVTLVI-------LAKSNPVDE-----------DTVNMLVLLPKDNSYMFSMDRVRPAV 50

  Fly    66 KVAEQQIR-SKSLIPSHIDFEWLAHDTKCDASLGVIKAMDGIIK-QCAQVIFGPVCDYSLAAVSR 128
            ..|.:.|: :::|:|. :.|..:.:|:.| .:..:...:|..:: |...||.||||:|:.|.|:|
Frog    51 DHALRSIQENQTLLPG-MHFNVIYNDSDC-GNQALFSLIDIAMQLQKPDVILGPVCEYAAAPVAR 113

  Fly   129 ITKYFNSQGTPLISVGGSTYDFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWSHSIF 193
            :..::|   .|::|.|.....|.||    ::|:..|.|...: :..:.|:.:.:.:.|.|:.:..
Frog   114 LASHWN---VPMLSAGALAIGFMQK----SNEYSHLTRVSPV-YSKMGEMFLAMFRYHKWTKAFL 170

  Fly   194 YYERDG-QRSVAGMHTCFLMMKSLGKQMRNENMTFAQFPLEPNLTNRTEEMRREIGNK 250
            .|..|. ||:      ||..::.:....:.|....:....:.......||:...|.||
Frog   171 LYTDDNLQRN------CFFTLEGVHLAFKEEGYAMSIHNFDETKHVDAEEIVHSIQNK 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	50/197 (25%)
npr3	XP_004910476.1	PBP1_NPR_C	25..414	CDD:380609	57/214 (27%)
npr3	XP_004910476.1	TM_EphA1	443..474	CDD:391457
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR44755
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010