DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31183 and GLR5

DIOPT Version :9

Sequence 1:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster
Sequence 2:	NP_565744.1	Gene:	GLR5 / 817801	AraportID:	AT2G32400	Length:	921	Species:	Arabidopsis thaliana

Alignment Length:	725	Identity:	121/725 - (16%)
Similarity:	248/725 - (34%)	Gaps:	196/725 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LVFVALLPSVESDNKNDCIMPKVLPV-----------------LELAIRHVQR-MGFVGGSHFDI 132
            :|.:.::|.       ||..|:::.:                 ||.|:..|.. ..|:  ...::
plant    15 IVVILVVPM-------DCQRPQLVNIGAVFAFDSVIGRAAKVALEAAVSDVNNDKSFL--KETEL 70

  Fly   133 QLISRDTFCSSKYGPIGFFEIYTQWPEVNAVFGLPCEYVLAPISRYADVWQVPVLTTGGNAKEFN 197
            :|:..|:.|:...|..|.||:..:  ||.|:.|.....|...||..|.....|:::..  |.:..
plant    71 RLLMEDSACNVFRGSFGAFELLEK--EVVAMIGPISSSVAHTISDIAKGLHFPLVSFA--ATDPT 131

  Fly   198 KKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAKVKGNSVCFLCLAAIHDTI- 261
            ..:..:....|......:.:..:| .::|.:.|.....:|.::.....|       ::|:.|.:
plant   132 LSALQFPFFLRTTPNDAHQMSALV-DLINFYGWKEVISVYSDDELGRNG-------VSALDDELY 188

  Fly   262 --EEHSVYQLGFDTSTWTKADITRMLKNVAMQSRIVIMCADPQSIRQIMLTAEELNMIDSGEYVF 324
              .....|::.....:..|.....:.|:.::..|:.|:...|..:.:|...|::|.|: :.|||:
plant   189 KKRSRISYKVPLSVHSDEKFLTNALNKSKSIGPRVYILHFGPDPLLRIFDIAQKLQMM-THEYVW 252

  Fly   325 INIELFSRVQYLTSQPWYDKNDTDLNNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKY 389
            :            :..|.......|:::...|....::.:....|            :::..|.:
plant   253 L------------ATDWLSVTLDSLSDKGTLKRLEGVVGLRQHIP------------ESVKMEHF 293

  Fly   390 NYTFSDNEPISAFVTSFFDGVLLYANALNESIRE---------DPTMLTRPI-----------NG 434
            .:....|..::|:....:|.|.:.|:.:.|.:.|         :..:..|..           :|
plant   294 THKLQSNRSMNAYALHAYDTVWMIAHGIEELLNEGINITFSYSEKLLHARGTKLHLEKIKFFNSG 358

  Fly   435 TDMVRRMWNRSFTGITGNVTIDANGDRLSA-YSLLDMNPT----------TGRFEIVA---HFLH 485
            ..::.::...:||||.|.|...:..:.:.. |.::::|.|          .|.|.:||   ....
plant   359 ELLLEKLLKVNFTGIAGQVQFGSGRNVIGCDYEIINVNKTDVHTVGFWSKNGGFSVVAPKTRHSQ 423

  Fly   486 NRLEFEANK---EIHWAGDREEAPPDRPICGYDGALCPDNSLP---------------------- 525
            .:..|.:::   :|.|.|...|.|        .|.:..|::.|
plant   424 KKTSFVSDEKLGDITWPGGGREKP--------RGWVIADSADPLKIVVPRRVSFVEFVTEEKNSS 480

  Fly   526 ----GYAILSIVLGTMVVVMAVCFFF----------GYRHYIAEAEINSMSWKVSLEDVMFRDAA 576
                |:.|...:.....|..:|.:.|          .|.|.|.           .:.|.:: |||
plant   481 HRIQGFCIDVFIEALKFVPYSVPYIFEPFGNGHSSPNYNHLIQ-----------MVTDGVY-DAA 533

  Fly   577 ERGLRGSFHSLVKQSSQLTLMSEDMVSINGDRQIFIPVGMFRKSKVAIKPVEVDNVQGLLTR--- 638
            ...:     ::|...|:|...|:...|          .|:     |.:.|...||...:..|
plant   534 VGDI-----AIVPSRSKLVDFSQPYAS----------TGL-----VVVIPANDDNATWIFLRPFT 578

  Fly   639 ---------SLMLELKRMKDLQHDHLVKFYGACLDQRRSFLLTEYCP--KGSLQDILEN--EQFQ 690
                     |.::....:..|:|.....|.|....|..:.||..:..  |.:.:|.:.|  ....
plant   579 SRLWCVVLVSFLVIAVVIWILEHRINEDFRGPPRRQLSTMLLFSFSTLFKRNQEDTISNLARLVM 643

  Fly   691 LDWMFRLSLM 700
            :.|:|.|.::
plant   644 IVWLFLLMVL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368	76/467 (16%)
		ANF_receptor	108..473	CDD:279440	65/406 (16%)
		PK_GC-A_B	589..883	CDD:270944	24/128 (19%)
		Pkinase_Tyr	613..877	CDD:285015	20/104 (19%)
		HNOBA	<893..938	CDD:285003
		CYCc	917..1108	CDD:214485
		Guanylate_cyc	944..1130	CDD:278633
GLR5	NP_565744.1	PBP1_GABAb_receptor	32..416	CDD:107361	68/422 (16%)
		ANF_receptor	46..396	CDD:279440	64/388 (16%)
		GluR_Plant	458..800	CDD:270404	38/228 (17%)
		Lig_chan	581..832	CDD:278489	14/73 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910