DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31183 and si:dkey-206f10.1

DIOPT Version :9

Sequence 1:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster
Sequence 2:	XP_009293230.1	Gene:	si:dkey-206f10.1 / 560719	ZFINID:	ZDB-GENE-041014-154	Length:	1187	Species:	Danio rerio

Alignment Length:	269	Identity:	81/269 - (30%)
Similarity:	139/269 - (51%)	Gaps:	30/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   909 EERTQDYHEEKKKCEKLLYQLLPQSVAAQLI----SGQPVVAETFDQVTIYFSDIVGFT------ 963
            ::..|:..:.::..|.||:.:||..||...:    :.|.:.::::|:|.:.|:.|.||.
Zfish   889 QQEVQEMRDLREHNECLLHNILPAHVARHFLERNRNDQELYSQSYDEVGVMFASIAGFNDYYEQK 953

  Fly   964 AISAESTPMQVVQFLNDLYTCFDSIVEN---FDVYKVETIGDAYMVVSGLP------IRNGNQHA 1019
            .|..|.  ::.::.||::...||.::|.   .|:.|::|||..||..|||.      :.|...|.
Zfish   954 EIKHEG--VECLKLLNEIIADFDELLEESYFLDIEKIKTIGSCYMAASGLSPDKQSRVVNDWHHL 1016

  Fly  1020 REIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMES 1084
            .|:...|||:.|.:.....|..  :..:||:|:..|..||||:|...|:|.::|.|||.||||:|
Zfish  1017 SELVLFALAMQETLREINKHSM--NNFQLRVGIAHGPVVAGVIGATKPQYDIWGMTVNLASRMDS 1079

  Fly  1085 NGEALKIHISETTKEALDEFGTFVTTRRGFVPMKG----KGEMLTYWL--EGEVPRPNSLISPSK 1143
            .|.:.:|.:.|.|:..|.::| ||...||.:.:||    ||.:.||::  :..:...|.:....|
Zfish  1080 TGVSGRIQVPEATRNILADWG-FVLELRGEIYIKGVSERKGRVRTYFISTKRRLVSSNGIADRGK 1143

  Fly  1144 LMLTRRSSL 1152
            ...|.|::|
Zfish  1144 NGHTGRTTL 1152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003	8/28 (29%)
		CYCc	917..1108	CDD:214485	65/209 (31%)
		Guanylate_cyc	944..1130	CDD:278633	67/206 (33%)
si:dkey-206f10.1	XP_009293230.1	AC_N	<135..380	CDD:292831
		CYCc	343..538	CDD:214485
		Guanylate_cyc	382..564	CDD:278633
		DUF1053	<611..661	CDD:283888
		CYCc	899..1097	CDD:214485	63/201 (31%)
		Guanylate_cyc	928..1126	CDD:278633	67/202 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810