Protein Alignment CG31183 and npr1a

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_001038402.1
• Gene: npr1a / 560653
• ZFINID: ZDB-GENE-060503-539
• Length: 1067
• Species: Danio rerio
• Alignment Length: 1125
• Identity: 472/1125 - (41%)
• Similarity: 677/1125 - (60%)
• Gaps: 131/1125 - (11%)

  Fly    52 PETKNSHKSQSTELVQHFPSLPMPDHRRLGARRQLVFVALLPSVESDNKNDCIMPKVLPVLELAI 116
            |::.::|.||                      :.:....:||.  .:.:.....|:|.|.|..|:
Zfish    35 PQSPSAHASQ----------------------KNITLAVILPL--HNTEYPWAWPRVGPALYWAL 75

  Fly   117 RHVQR-MGFVGGSHFDIQLI-----SRDTFCSSKYGPIGFFEI---YTQWPEVNAVFGLPCEYVL 172
            ..|.. ...:.|.|  :||:     :::..||....|:...::   |..|    |..|..|:|..
Zfish    76 EKVNSDPNLLAGYH--LQLVFNSSENKEGLCSDSVAPLVAVDLKFSYNPW----AFIGPGCDYSS 134

  Fly   173 APISRYADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIY 237
            :|::|:...|:||::|:|..|..||    .||::|.: |.....||..|..:...|.|.:.|::.
Zfish   135 SPVARFTTHWEVPMITSGARALGFN----LYSSITNI-GPTHKKLGEFVLRMHRHFGWDKHAMLM 194

  Fly   238 QNENAKVKGNSVCFLCLAAIHDTIEEHSVYQLGFDTSTWTKADIT-----------RMLKNVAMQ 291
            .|:|.  ..:..|:..:...:..:.|.::          |..|:.           .:|::::.:
Zfish   195 FNDNK--NDDRPCYFAVEGPYTQMREDNI----------TADDLVFNEDEEPLRYDELLRDISHK 247

  Fly   292 SRIVIMCADPQSIRQIMLT------AEELNMIDSGEYVFINIELFSR-VQYLTSQPWYDKNDTDL 349
            :|:|.:|...::.|::|:.      .:|       ||.|..|:||.| :|...::|| .:.|.|.
Zfish   248 ARVVYVCCKWETFRKLMVEFWRQGFPQE-------EYAFFFIDLFGRSLQSHPARPW-ARGDADD 304

  Fly   350 NNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKYNYTFSDNEPISAFVTSFFDGVLLYA 414
            |  .|::|:.::..:|.::|.:.||....:::|..|.:.:|:...|: .::....||.|||:||:
Zfish   305 N--AAKEAFKSVKILTYREPQNPEYKDFVSKLKTEAMDMFNFNVEDS-LMNLISGSFHDGVMLYS 366

  Fly   415 NALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMNPT-TGRFE 478
            :|||:::....   :|| .|..:.:|||||::.|:||.|.:|.||||...::|.||..| ||.::
Zfish   367 HALNDTMDRSG---SRP-PGDVVNKRMWNRTYHGVTGLVQLDENGDREIDFALWDMTDTKTGDYQ 427

  Fly   479 IVAHF--LHNRLEFEANKEIHWAGDREEAPPDRPICGY--DGALCPDNSLPGYAILSIVLGTMVV 539
            ||:.:  ...::..|...::||...|  .|||.|.||:  |...|...::..:.::|||:..:.:
Zfish   428 IVSVYNGSQKQMILEPGMKVHWLKGR--PPPDIPECGFKNDNPACLAKTVTMHQMISIVVCFIFI 490

  Fly   540 VMAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRDAAERGLRGSFHSLVKQSSQLTLMSE----- 599
            ::.....|.||....|.|:.:..|:|..||:...: .|:.||       :..|:||:...
Zfish   491 IIVTVTVFIYRKLKLENELTAQLWRVHWEDIQMSN-TEKVLR-------RACSKLTISLRGSNYG 547

  Fly   600 DMVSINGDRQIFIPVGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFYGACLD 664
            .:::::|:.||:...|.::.:..|||.|....::  |||.::.|||.|:|:|::||.:|.|||:|
Zfish   548 SLLTMDGNFQIYAKTGYYKGNITAIKYVNKKRIE--LTRKVLFELKHMRDVQNEHLTRFIGACID 610

  Fly   665 QRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNCVVD 729
            .....:||||||:|||||::|:|...||||||.||::|||:||.|||:|.|.|||||||||||||
Zfish   611 PPNICILTEYCPRGSLQDLMESEGITLDWMFRYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVD 675

  Fly   730 SRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHNRPPEGTQKGDVYAF 794
            |||||||||:||.:..:       |....:.||::::.|||||||||.: |.|..||||||||:|
Zfish   676 SRFVLKITDYGLESFHK-------DSNLDDVHAFYARQLWTAPELLRAD-NPPACGTQKGDVYSF 732

  Fly   795 GIIVHEITTRQGPFYL-GRCAYEKSPQEIIE-LVKGYNPHRMQKPFRPELEPNGDTKADINGIIR 857
            |||:.|:...:|.||| |.|.   ||:|||| :|:|..|:     .||.|.|...:: ::..::.
Zfish   733 GIILQELALLKGVFYLEGPCL---SPKEIIERVVEGRWPY-----LRPLLCPQSHSE-EMGQLML 788

  Fly   858 RCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQDYHEEKKKC 922
            |||:||..|||||:.:|.::|: |......||:||||.|||.||||||||||||||.|||||:|.
Zfish   789 RCWSEDVNERPDFSQIKVLLRK-NNCGYGSNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKA 852

  Fly   923 EKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDS 987
            |.||||:||.|||.||..|:.|.||.||.|||||||||||||:|||||||:||..|||||||||:
Zfish   853 EALLYQILPHSVAEQLKRGEMVQAEAFDSVTIYFSDIVGFTALSAESTPMEVVTLLNDLYTCFDA 917

  Fly   988 IVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGL 1052
            |::|||||||||||||||||||||:|||..|||||||::||||||||:|||.|||..:|:||||:
Zfish   918 IIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLEAVHSFRIRHRPNLQLRLRIGI 982

  Fly  1053 HTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPM 1117
            |:|...||||||||||||||||||||||||||||||||||:||.|:..|.||..|....||.|.|
Zfish   983 HSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSEATRAVLQEFNCFQLELRGDVEM 1047

  Fly  1118 KGKGEMLTYWLEGEVPRPNS 1137
            ||||.|.||||.||:...|:
Zfish  1048 KGKGRMRTYWLLGEISSNNA 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596	113/435 (26%)
		PK_GC-A_B	589..883	CDD:270944	141/300 (47%)
		HNOBA	<890..938	CDD:462234	37/47 (79%)
		CYCc	917..1108	CDD:214485	146/190 (77%)
npr1a	NP_001038402.1	PBP1_NPR_A	48..449	CDD:380608	113/440 (26%)
		PK_GC-A_B	540..814	CDD:270944	138/293 (47%)
		HNOBA	<820..868	CDD:462234	37/47 (79%)
		CYCc	847..1032	CDD:214485	143/184 (78%)