Protein Alignment CG31183 and NPR3

DIOPT Version :9

• Sequence 1: NP_001287342.1
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_001191304.1
• Gene: NPR3 / 4883
• HGNCID: 7945
• Length: 541
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 154/569 - (27%)
• Similarity: 259/569 - (45%)
• Gaps: 82/569 - (14%)

  Fly    35 GGVASIGVGSDEHSFKTPETKNSHKSQSTELVQHFPSLPMPDHRRLGARRQLVFVALLPSVESDN 99
            ||.|.||.|..|.....|:                               ::..:.|||   .|:
Human    33 GGGAGIGGGRQEREALPPQ-------------------------------KIEVLVLLP---QDD 63

  Fly   100 KNDCIMPKVLPVLELAIRHVQRMG-----FVGGSHFDIQLISRDTFCSSKYGPIGFFEIY----- 154
            .....:.:|.|.:|.|:|.|:..|     ...|:.|  |:...|:.|.::    ..|.:.
Human    64 SYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRF--QVAYEDSDCGNR----ALFSLVDRVAA 122

  Fly   155 TQWPEVNAVFGLPCEYVLAPISRYADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGN 219
            .:..:.:.:.|..|||..||::|.|..|.:|:|:.|..|..|..|...||.|||:..|.. .:|.
Human   123 ARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYA-KMGE 186

  Fly   220 VVRAILNSFNWTRTALIYQNENAKVKGNSVCFLCLAAIHDTIEEHSVYQLGFDTSTWTKADITRM 284
            ::.|:....:|:|.||:|.::  |::.|  |:..|..:|:..:|..::...:........|:..:
Human   187 MMLALFRHHHWSRAALVYSDD--KLERN--CYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDI 247

  Fly   285 LKNVAMQSRIVIMCADPQSIRQIMLTAEELNMIDSGEYVFINIELFSRVQYLTSQPWY--DKNDT 347
            ::|:....|:|||||...:||.|||.|....| .||:|.|.|||||:...| ....|.  ||:|.
Human   248 VRNIQASERVVIMCASSDTIRSIMLVAHRHGM-TSGDYAFFNIELFNSSSY-GDGSWKRGDKHDF 310

  Fly   348 DLNNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKYNYTFSDNEPISAFVTSFFDGVLL 412
            :     |::||:::.|||..:....|:.:.|.|:|: :.||......|.  ::.||..|.|.:||
Human   311 E-----AKQAYSSLQTVTLLRTVKPEFEKFSMEVKS-SVEKQGLNMEDY--VNMFVEGFHDAILL 367

  Fly   413 YANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMNPT-TGR 476
            |..||:|.:|...:..    :|..::::.|||:|.||.|.|:|||||||...:|::.|... .|.
Human   368 YVLALHEVLRAGYSKK----DGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGT 428

  Fly   477 FEIVAHFL--HNRLEFEANKEIHWAGDREEAPPDRPICGYDGALCPDN-SLPGYAILSIVLGTMV 538
            .|::..:.  ..|.|...|.:..|...:.....:|.:...:.:.|..: .|...|:..||:|.::
Human   429 QEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALL 493

  Fly   539 ---VVMAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRDAAERGLRGSF 584
               ::||  |:|..:.|....|..:...:.:|.  ..|:..|..:|..|
Human   494 GAGLLMA--FYFFRKKYRITIERRTQQEESNLG--KHRELREDSIRSHF 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368	127/424 (30%)
		ANF_receptor	108..473	CDD:279440	118/376 (31%)
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003
		CYCc	917..1108	CDD:214485
		Guanylate_cyc	944..1130	CDD:278633
NPR3	NP_001191304.1	PBP1_NPR_C_like	54..446	CDD:107381	126/419 (30%)
		ANF_receptor	71..422	CDD:279440	117/375 (31%)
		TM_EphA1	476..507	CDD:214014	9/32 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3721
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810