Protein Alignment CG31183 and Npr2

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_776149.1
• Gene: Npr2 / 230103
• MGIID: 97372
• Length: 1047
• Species: Mus musculus
• Alignment Length: 1091
• Identity: 479/1091 - (43%)
• Similarity: 651/1091 - (59%)
• Gaps: 101/1091 - (9%)

  Fly    84 RQLVFVALLPSVESDNKNDCIMPKVLPVLELAIRHVQRMGFVGGSHFDIQLISR--DTFCSSKYG 146
            |.|....:||  |.:.......|:|.|.:.||:..:.|     ....|::.:|.  |..||....
Mouse    23 RNLTLAVVLP--EHNLSYAWAWPRVGPAVALAVEALGR-----ALPVDLRFVSSELDGACSEYLA 80

  Fly   147 PIGFFEIYTQWPEVNAVFGLPCEYVLAPISRYADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKG 211
            |:...:: ..:.:.:.:.|..|.|..|.::|:|..|::|:||.|..|..|..|:|.|.||.| .|
Mouse    81 PLRAVDL-KLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFAAKNEHYRTLVR-TG 143

  Fly   212 AQVNNLGNVVRAILNSFNWT-RTALIYQNENAKVKGNSVCFLCLAAIHDTIE------EHSVYQL 269
            .....||..|..:...|||| |.||:|.:.....:.:   :..:..:.:.::      :|.||..
Mouse   144 PSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH---YFTIEGVFEALQGSNLSVQHQVYAR 205

  Fly   270 ---GFDTSTWTKADITRMLKNVAMQSRIVIMCADPQSIRQIMLTAEELNMIDSGEYVFINIELFS 331
               |.:.:|          ..:....|||.:|...:.:.:|:|.|:..| :.:|:|||..:::|.
Mouse   206 EPGGPEQAT----------HFIRANGRIVYICGPLEMLHEILLQAQREN-LTNGDYVFFYLDVFG 259

  Fly   332 R-----VQYLTSQPWYDKNDTDLNNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKYNY 391
            .     ....|.:||.| |.|....:..::|:..:|.:|.::|.:.||....|.:...|.|.:..
Mouse   260 ESLRAGPTRATGRPWQD-NRTQEQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGV 323

  Fly   392 TFSDNEPISAFVTSFFDGVLLYANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTID 456
            ..:.: .::.....|:||:||||..|||:|:|..|.    .:|..:|.:|..|.:.|:||.|.:|
Mouse   324 ELAPS-LMNLIAGCFYDGILLYAQVLNETIQEGGTR----EDGLRIVEKMQGRRYHGVTGLVVMD 383

  Fly   457 ANGDRLSAYSLLDMNP-TTGRFEIVAHFLHNRLEFEANKEIHWAGDR----EEAPP-DRPICGY- 514
            .|.||.:.:.|..|.. .:|.|:..||:      ..|.|:|.|.|..    :.||| |.|.|.:
Mouse   384 KNNDRETDFVLWAMGDLDSGDFQPAAHY------SGAEKQIWWTGRPIPWVKGAPPLDNPPCAFD 442

  Fly   515 -DGALCPDNSLPGYAILSIVLGTMVVVMAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRDAAER 578
             |...|....|...||:::..|...::..|..|..:|..:.|.|:.||.|::..|::.|.: ::|
Mouse   443 LDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGN-SDR 506

  Fly   579 GLRGSFHSLVKQSSQLTLMSE-----DMVSINGDRQIFIPVGMFRKSKVAIKPVEVDNVQGLLTR 638
            ..:|:       .|:|||...     .:::.:|..|||...|.|:.:.||||.|....::  |||
Mouse   507 YHKGA-------GSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIE--LTR 562

  Fly   639 SLMLELKRMKDLQHDHLVKFYGACLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDI 703
            .::.|||.|:|:|.:||.:|.|||:|.....::|||||:|||||||||:...||||||.||::|:
Mouse   563 QVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDL 627

  Fly   704 VRGMQFLHSSDIRSHGNLKSSNCVVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLL 768
            |:||.|||:|.|.|||:||||||||||||||||||:||.:.|.|   .|.|    :|||.::|.|
Mouse   628 VKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRST---AEPD----DSHALYAKKL 685

  Fly   769 WTAPELLRVEHNRPPEGTQKGDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVK-GYNPH 832
            |||||||. .:..|..|.||.|||:|.||:.||..|.|||||.  ..:.||:||::.|: |..|:
Mouse   686 WTAPELLS-GNPLPTTGMQKADVYSFAIILQEIALRSGPFYLE--GLDLSPKEIVQKVRNGQRPY 747

  Fly   833 RMQKPFRPELEPNGDTKADING----IIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNL 893
                 |||.::     :..:|.    ::.||||:||.|||||..:|..||||||:..| :|:|||
Mouse   748 -----FRPSID-----RTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGT-SILDNL 801

  Fly   894 LKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSD 958
            |.|||.||||||:|||||||.|.|||:|.|.||||:||.|||.||..|:.|.||.||.|||||||
Mouse   802 LLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSD 866

  Fly   959 IVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIA 1023
            ||||||:||||||||||..|||||||||:|::|||||||||||||||||||||.|||.:||.|||
Mouse   867 IVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIA 931

  Fly  1024 RLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEA 1088
            |:|||||:||.:|||.|||.|:|:||||:|||...||||||||||||||||||||||||||||:|
Mouse   932 RMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQA 996

  Fly  1089 LKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEGEVPRPNSLI 1139
            ||||:|.|||:||||.|.|....||.|.|||||:|.||||.||...|..|:
Mouse   997 LKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGEQKGPPGLL 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596	110/423 (26%)
		PK_GC-A_B	589..883	CDD:270944	147/303 (49%)
		HNOBA	<890..938	CDD:462234	35/47 (74%)
		CYCc	917..1108	CDD:214485	149/190 (78%)
Npr2	NP_776149.1	PBP1_NPR_B	26..421	CDD:380607	113/429 (26%)
		PK_GC-A_B	518..792	CDD:270944	143/295 (48%)
		HNOBA	<798..846	CDD:462234	35/47 (74%)
		CYCc	825..1009	CDD:214485	144/183 (79%)