Protein Alignment CG31183 and gcy-37

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_500171.2
• Gene: gcy-37 / 191658
• WormBaseID: WBGene00001557
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 143/624 - (22%)
• Similarity: 259/624 - (41%)
• Gaps: 164/624 - (26%)

  Fly   551 HYIAEAEINSMSWKVSLEDVMFR--DAAERGLRGSFHS-----------LVKQSSQLTLMSED-- 600
            ||.    |:.:::|..::...|:  ...|.||:..:.|           ||::::: ||...|
 Worm   105 HYF----IDQIAFKSEMKGPTFQCEPFGESGLKLHYFSFRQGLFPIVKGLVRKTAR-TLFEMDVK 164

  Fly   601 --MVSINGDRQIFIPVGMFRKSKVAIKPVE-----------------VDNVQGL-LTRSLMLELK 645
              |:..|.:|:   ..||......:::|.:                 .:|.... |:.::::.|:
 Worm   165 VCMLERNQERR---KSGMVEHVIFSVEPDDNHRKGKRLFHKFRNTKTTENAPSFTLSSTILVGLR 226

  Fly   646 RMKDLQHDHLVKFYGACLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFL 710
            ..|::...|:.......::....:||.||.        |||::     ..::|   |:   ||.:
 Worm   227 DFKNIFPYHVCFNKQMIIEHIGIYLLREYG--------LENKK-----TLKVS---DL---MQLV 272

  Fly   711 HSSDIR-SHGNLKSSNCVVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPEL 774
            ..|||: ::.|:.|.                |:||                            .:
 Worm   273 QPSDIQLTYKNVLSY----------------LNTL----------------------------FI 293

  Fly   775 LRVEHNRPPEGTQKGDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVKGYNPHRMQKPFR 839
            .:::|:......|:|...||          |.|..|                ||
 Worm   294 FQLKHHSKRNEVQEGSSEAF----------QQPLVL----------------KG----------- 321

  Fly   840 PELEPNGDTKADINGIIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIV---DNLLKRMELYA 901
             |:.|..|.    |.||..|.......| |...||..|......:.|.::|   .:.:.:||| .
 Worm   322 -EMMPINDG----NSIIFICSPHVTTVR-DILNLKLYISDMPMHDATRDLVMLNQSRICQMEL-N 379

  Fly   902 NNLEEL---VEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFT 963
            ..|||.   :::.|::...:|.:.::||::.:|..:|..|.:.:.|.|:.|...::.|:||..|.
 Worm   380 KKLEETMKKMKKMTEELEVKKSQTDRLLFEFVPPVIAEALRAAKTVPAQEFSDCSVIFTDIPDFF 444

  Fly   964 AISAESTPMQVVQFLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQ-HAREIARLAL 1027
            .||...:|.:::..:.||:..||.|:|....|||.::.|:|::|.|:|  |.|| |..:...|||
 Worm   445 TISVNCSPTEIITVVTDLFHRFDRIIEKHKGYKVLSLMDSYLIVGGVP--NANQYHCEDSLNLAL 507

  Fly  1028 ALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIH 1092
            .||...... :..:.|..::||||:|.|..|||:|..:.||:|:.|:|||....:.|:....|:.
 Worm   508 GLLFEAKQV-VVPKLERSVRLRIGVHCGPVVAGIVSQQKPRFCVLGNTVNVTKSICSHSSPGKVL 571

  Fly  1093 ISETTKEALDEF--GTFVTTRRGFVPMKGKGEMLTYWLE 1129
            :|...:..:.:.  ..||....|::.:: .|::||::||
 Worm   572 VSNAVRTMVTKHLKSIFVFNANGYLELQ-SGKVLTHFLE 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596
		PK_GC-A_B	589..883	CDD:270944	55/316 (17%)
		HNOBA	<890..938	CDD:462234	13/53 (25%)
		CYCc	917..1108	CDD:214485	60/193 (31%)
gcy-37	NP_500171.2	HNOB	3..165	CDD:462233	14/64 (22%)
		HNOBA	223..419	CDD:462234	58/302 (19%)
		CYCc	400..577	CDD:214485	60/179 (34%)