Protein Alignment CG31183 and gcy-15

DIOPT Version :9

• Sequence 1: NP_001287342.1
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_001364713.1
• Gene: gcy-15 / 191648
• WormBaseID: WBGene00001541
• Length: 1104
• Species: Caenorhabditis elegans
• Alignment Length: 1093
• Identity: 348/1093 - (31%)
• Similarity: 540/1093 - (49%)
• Gaps: 183/1093 - (16%)

  Fly   179 ADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAK 243
            :||.::.:    .:.|.|::.|.       |..:|.|:|...|...|:.:.|.:.||:
 Worm    71 SDVCEMDL----SSVKGFDQTSV-------LMNSQTNSLAKSVMYFLDKYQWKKVALV------- 117

  Fly   244 VKGNSVCFLCLAA-----IHDTIEEHSVYQLGFDTSTWTKADITRMLKNVAMQSRIVIMC---AD 300
              ..|......||     :.|.:..:.: .:..|:.....:|||..:|..|.::||.|:|   ::
 Worm   118 --SPSAVLTAFAARVRSDLLDALTANKI-DILVDSRLDPMSDITEKVKEDAEKARIFIICDWSSN 179

  Fly   301 PQSIRQIMLTAEELNMIDSGEYVFINIELFSRVQYLTSQPWY---------------DKNDTDLN 350
            ...:|..:....|:|.:.||||..:..     :.|.|:..|.               |.||.:|.
 Worm   180 ANLLRNYIFKLGEMNKMQSGEYFVLGY-----ISYDTNYQWLEASSGDQRLVHLGASDINDYNLT 239

  Fly   351 NERAQKAYTAMLTVT----PKQPN---DNEYTRVSNEIKAIAAEKY-NYTFSDN-EPISAFVTSF 406
            .....:.|..::.::    |.:||   ::..|:|..:..|.....| |.|.|:. .|....:...
 Worm   240 ENDLHEVYKNVVILSDGPPPAEPNSTWEDIKTQVLKKKPAKMCPPYCNTTISEKITPRWDRIKLL 304

  Fly   407 FDGVLLYANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMN 471
            ||.:...|:|.|:::.....:....|....::.|..: |.||:|         :.:..|..:
 Worm   305 FDSIQYLADATNDALNIGANIYQSDIFYEHLISRKVD-SVTGVT---------EYIDGYGAI--- 356

  Fly   472 PTTGRFEIVAHF---LHN--------RLEFEANKEIHWA-GDREE----------APPDRPICGY 514
              .|..:|..||   .||        ||...:.....|: .|..|          ||.|.|:||:
 Worm   357 --VGSMQIYYHFSSSSHNSYSLFPCARLAQSSLLNTVWSLTDYSEGLSIDFVNKSAPKDTPVCGF 419

  Fly   515 DGALC--PDNSLPGYAILSIVLGTMVVV-MAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRD-- 574
            .|..|  |.|:.   .|:.|.:|..|:: :|:...|.|:.|..|..::|:.:.:....::.:.
 Worm   420 YGENCGPPANNT---FIIVISVGVAVLIGLAIAAAFLYKRYRYERRLHSLFFMIDRNQIILKKHT 481

  Fly   575 --AAERGLR--GSFHSLVKQSSQLTLMSEDMV-------SINGDRQIF----------------- 611
              .:::.||  .|.|..|..:||....|...:       |||.. .||
 Worm   482 NLMSQQSLRSMASIHGSVVAASQTLRDSHFFIEDYNNASSINAS-SIFNTGSTARAGPFGPIPGF 545

  Fly   612 --------------IP---VGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFY 659
                          ||   ||::....||:|.:...:|:  .|||..||:.::::..:.::::|.
 Worm   546 GGVTGASEDEKWHQIPDFGVGLYEGRTVALKRIYRSDVE--FTRSNRLEIAKLQESVNSNVIEFV 608

  Fly   660 GACLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSS 724
            |..:.....|::.|...:|||:|||:|:...||.:||..:..||:.|:::||||.:..||.|||:
 Worm   609 GMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSSPVGCHGRLKST 673

  Fly   725 NCVVDSRFVLKITDFGLHTLR-RTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHNRPPEG--- 785
            ||::|:|::::::.|||..|| ...:..|.|.......      |||:|||||........|
 Worm   674 NCLIDARWMVRLSSFGLRELRGEETWQQEDDVQEGKDQ------LWTSPELLRWSTGLSQCGVLL 732

  Fly   786 TQKGDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVK-----GYNPHRMQKPFRPELEPN 845
            .||.|||:..|:::|:..|.||:  |....|  |:||:.|||     |      :|||||::...
 Worm   733 VQKSDVYSLAIVLYELFGRLGPW--GDEPME--PREIVSLVKREALAG------KKPFRPDMAVL 787

  Fly   846 GDTKADINGIIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEE 910
            .::...:...:...|.|||..||..:.:|..::......:. .|:||::..:|.|.:.||:.:.|
 Worm   788 KESPRIVQETVVAAWTEDPLNRPSLHQIKRKLKPLTIGLKR-TIMDNMVSMIEKYTDKLEKDIAE 851

  Fly   911 RTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVV 975
            |.::...||.|.|.||..:||:.||..|..|..|.||:|:..|::|||..||..:||.|.|:.:|
 Worm   852 RNEELEAEKAKSEALLKMMLPEVVADSLKLGSNVSAESFENCTVFFSDCPGFVEMSATSKPIDIV 916

  Fly   976 QFLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHH 1040
            ||||||||.||.|::.|||||||||.|||||.||||:.|||.||.|||.|.||||:||.:|:|.|
 Worm   917 QFLNDLYTVFDRIIDQFDVYKVETIADAYMVASGLPVPNGNHHAGEIASLGLALLKAVESFKIRH 981

  Fly  1041 RPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFG 1105
            .|.::::||||:::|.||||||||||||||||||||||||||||||..|:|:.|.|.||.||:.|
 Worm   982 LPNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGIPLRINCSGTAKEILDQLG 1046

  Fly  1106 TFVTTRRGFVPMKGKGEMLTYWLEGEVPRPNSLISPSKLMLTR--RSSLKQPQ 1156
            .:....||.|.|||||:.:||::.||    ||.:...:::..|  .:|||:.|
 Worm  1047 GYEIEERGIVEMKGKGKQMTYFVRGE----NSDMRRERIIRERVKFASLKKAQ 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368	74/361 (20%)
		ANF_receptor	108..473	CDD:279440	66/325 (20%)
		PK_GC-A_B	589..883	CDD:270944	99/343 (29%)
		Pkinase_Tyr	613..877	CDD:285015	90/275 (33%)
		HNOBA	<893..938	CDD:285003	16/44 (36%)
		CYCc	917..1108	CDD:214485	119/190 (63%)
		Guanylate_cyc	944..1130	CDD:278633	117/185 (63%)
gcy-15	NP_001364713.1	Periplasmic_Binding_Protein_type1	2..363	CDD:415822	67/332 (20%)
		PK_GC	553..822	CDD:270894	91/286 (32%)
		HNOBA	<831..879	CDD:400168	18/47 (38%)
		Guanylate_cyc	885..1071	CDD:306677	117/185 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I1226
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920