Protein Alignment CG31183 and gcy-14

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_506660.2
• Gene: gcy-14 / 191647
• WormBaseID: WBGene00001540
• Length: 1111
• Species: Caenorhabditis elegans
• Alignment Length: 1093
• Identity: 376/1093 - (34%)
• Similarity: 550/1093 - (50%)
• Gaps: 146/1093 - (13%)

  Fly   123 GFVGGSHFDIQLISRDTFCSSKYGPIGFFEIYTQWPEVNAVFGLPCEYVLAPISRYADVWQVPV- 186
            |..||.  .::||:.|                    .|:.:.|..|......::..|..:.|||
 Worm    76 GLAGGK--TVELINHD--------------------NVDVIIGPTCNRAGIAVASLAAYYNVPVF 118

  Fly   187 ---LTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAKVKGNS 248
               |||   |.:....|...:|:|.........||  ||.:|..|.|.....||.|:..:.|
 Worm   119 QWGLTT---AADIGNVSRYPTTVTLSLDTHSMALG--VREVLRRFEWDEFVFIYSNDGDEEK--- 175

  Fly   249 VCFLCLAAIHDTIE----EHSVYQLGF--DTSTWTKADITRMLKNVAMQSRIVIMC-ADPQSIRQ 306
                | |::.|.:|    |:|...|.:  ...|.|...:.:.|..|:.:.||:|.| |:.:..::
 Worm   176 ----C-ASMKDDLEKMGIENSDVTLAYMVQIQTVTLDALQKALTEVSKRGRIIIACFANGRGFKK 235

  Fly   307 IMLTAEELNMIDSGEYVFINIELFSR---VQYLTSQPWYDKNDTD------LNNERAQKAYTAML 362
            ..:.:..|..:.:.||:::..|..||   |..:.....|..:|||      |..|:.:.||..:|
 Worm   236 AFVASTVLAGMSTDEYMYMFAEPQSRGFYVDEINGGEHYSWDDTDGNFVTGLTPEQIRDAYGKVL 300

  Fly   363 ----------TVTPKQPNDNEYTRVSNE-IKAIAAEKYN----YTFSDNEPISAFVTSFFDGVLL 412
                      |:||      |:...|:: |..:..:.:|    .:.|..:..:.:....||....
 Worm   301 YICDNMGLPTTITP------EFANFSSQLISRMTEQPFNCVQDCSNSTYKVPATYAGQLFDAFYA 359

  Fly   413 YANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGI-TGNVTIDANGDRLSAYSLLDMNPTTGR 476
            |..|||.|:.:|||..... ||:.::..: ..||.|: .|.||:|..|.|:....:..:|.:...
 Worm   360 YGVALNRSLTQDPTRANLK-NGSFVLSDI-GMSFQGVGGGTVTLDDTGTRIVQVYMFALNTSLLP 422

  Fly   477 FEIVAHFLHNRLEFEANKEIHWAGDREEAPP-DRPICGYDGALCPDNSLPGYAILSIVLGTMVV- 539
            : :.|..:.|..|.|.........|.....| .|||||:.|..||.:.:..|.:.:|:...:||
 Worm   423 Y-LAASLVINGSEVEYTPFYKSEADLWSVRPLARPICGFSGLECPPDFVKEYLVYTIIAAVIVVL 486

  Fly   540 -VMAVCFFFGYRHYI--AEAEINSMSWKV---SLEDVMFRDAAERGLRGSFHSLVKQSSQLTLMS 598
             ::|.|....|...:  .|.|...:.|:|   .|:.|..:..||..:. ||.|....|:::|:.|
 Worm   487 ALLAGCAGLLYTMQMKRKEMERQDLLWQVPFIELQQVQSKSKAEASMH-SFASGPSTSTKITVES 550

  Fly   599 EDMVSINGDRQIFIPVGMFRKSKVAIKP---VEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFYG 660
            .. .:||     ||.....:....|:|.   ::.|..|       ..|.::|::..:|:|.||.|
 Worm   551 RS-ETIN-----FIFYYYQQDILAAMKHDLILQFDAEQ-------KAEFRQMRNFDNDNLNKFIG 602

  Fly   661 ACLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSN 725
            .|||..:.|.|..:|.:|||.|::.....|:|..|..||:.||..|:.|:|:|.::.||:|.|..
 Worm   603 LCLDGPQLFSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLLFIHNSFLKCHGHLTSRC 667

  Fly   726 CVVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEH-NRPPEGTQKG 789
            |::|.|:.:||:.:||.::|......:.|            ||||.||.||.|: .|.||    |
 Worm   668 CLIDDRWQIKISGYGLKSVRTFENPKKED------------LLWTPPENLRNENEERLPE----G 716

  Fly   790 DVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVK--GYNPHRMQKPFRPELEPNGDTKADI 852
            |:|:||||..||.||...|.|..  .::.|..||..||  |:|      |.||.|: .|:| .:|
 Worm   717 DIYSFGIICSEILTRSSAFDLEN--RKEKPDVIIYQVKKGGHN------PMRPSLD-TGET-VEI 771

  Fly   853 N----GIIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQ 913
            |    .:||.||.|.|:|||....::..:... :|....|::|::...:|.||:.|||.|.:||:
 Worm   772 NPALLHLIRDCWTERPSERPSIEQVRGHLNGM-RDGRKSNLMDHVFNMLETYASTLEEEVSDRTK 835

  Fly   914 DYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFL 978
            :..|||||.:.|||::||:.||.:|..||.|..|||:||||:|||:|.||.::.:.||:|||..|
 Worm   836 ELVEEKKKSDVLLYRMLPKMVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLAGKCTPLQVVTLL 900

  Fly   979 NDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPE 1043
            |||||.||.|:|..||||||||||.|:.|||||.||||:|.|.|||::|..|.::..||:.|.|.
 Worm   901 NDLYTIFDGIIEQNDVYKVETIGDGYLCVSGLPHRNGNEHIRHIARMSLGFLSSLEFFRVQHLPS 965

  Fly  1044 DRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDE-FGTF 1107
            :|:.||||::.|:.|||||||.|||||||||.|||||||||||:..|||::....:.|.: .|.|
 Worm   966 ERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGKIHVTAEANQMLTQVVGGF 1030

  Fly  1108 VTTRRGFVPMKGKGEMLTYWLEGEVPRPNSLISPSKLMLTRRSSLKQPQRSQS 1160
            .|..||.|.:||||.|.||||.||    .|.||.|  ....|....:|.|.||
 Worm  1031 RTESRGEVIIKGKGVMETYWLLGE----QSRISVS--AQAPREKTPEPPRRQS 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596	97/405 (24%)
		PK_GC-A_B	589..883	CDD:270944	101/303 (33%)
		HNOBA	<890..938	CDD:462234	22/47 (47%)
		CYCc	917..1108	CDD:214485	113/191 (59%)
gcy-14	NP_506660.2	PBP1_NPR_GC-like	21..419	CDD:380575	93/385 (24%)
		Protein Kinases, catalytic domain	535..800	CDD:473864	104/303 (34%)
		HNOBA	<816..860	CDD:462234	21/43 (49%)
		CYCc	839..1031	CDD:214485	113/191 (59%)