DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31183 and acy-3

DIOPT Version :9

Sequence 1:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster
Sequence 2:	NP_497765.4	Gene:	acy-3 / 175489	WormBaseID:	WBGene00000070	Length:	1243	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	81/375 - (21%)
Similarity:	152/375 - (40%)	Gaps:	79/375 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   884 NETG----NIVDNLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLP----QSVAAQLIS 940
            |.||    :..|.|.:...|.|.|..|  .|.|.::  :..:..|||...||    .....|:..
Worm   156 NFTGIYLCSTADRLARNAFLSARNSSE--AESTAEF--QSNRLNKLLSSFLPYHLINQARHQITL 216

  Fly   941 GQP-VVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDVYKVETIG-DA 1003
            .:| :..||:.||::.:..:|||.::.|:.:.:...:.|.:|.:..:.:..:....:|.:.| .|
Worm   217 YKPHLYNETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIERLAASNGCTRVASEGITA 281

  Fly  1004 YMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPR 1068
            ...:.|:    .:|||.::.|.::.|...:::||.....:  :.:.||:.:|...|||||:....
Worm   282 VCSIPGI----DSQHATKLCRFSMELETLINSFRDATGAD--VSVCIGIDSGPVTAGVVGVSKWH 340

  Fly  1069 YCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEGEVP 1133
            |.:.|...:.|..|:||.....:::|..|:..|...|.|...:   .|:..|       |.|.:|
Worm   341 YDVIGSVFDNALLMQSNATEPGVYVSNETRRFLGSTGEFELEK---CPIGWK-------LYGHLP 395

  Fly  1134 RPNSLISPSKLMLTRRSSLKQPQRSQSHNLHKQYSELVVASPPPQLPPPAIALPPPPSPSKDSPN 1198
            .|.  :.|                     ::|::|.:.|.....::....:|:    :|:..:..
Worm   396 SPE--LFP---------------------VNKRFSLVTVPQAVNRVLQSIVAM----NPTLKTMG 433

  Fly  1199 LRVKRK--------------------ISSSSPKLNGGGF--DYHKTENHY 1226
            ...|||                    ||:.|.:....|.  :|||..:|:
Worm   434 TNKKRKGEKSQEKFDMQKKKVEHSTIISTLSQRFRNPGLEAEYHKETDHW 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003	12/48 (25%)
		CYCc	917..1108	CDD:214485	46/196 (23%)
		Guanylate_cyc	944..1130	CDD:278633	43/186 (23%)
acy-3	NP_497765.4	TctB	26..137	CDD:284693
		CYCc	195..378	CDD:214485	45/188 (24%)
		Nucleotidyl_cyc_III	221..382	CDD:299850	40/166 (24%)
		CYCc	696..873	CDD:214485
		Nucleotidyl_cyc_III	711..880	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900