Protein Alignment CG31183 and gucy2f

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_571939.2
• Gene: gucy2f / 140424
• ZFINID: ZDB-GENE-011128-7
• Length: 1107
• Species: Danio rerio
• Alignment Length: 992
• Identity: 341/992 - (34%)
• Similarity: 514/992 - (51%)
• Gaps: 139/992 - (14%)

  Fly   201 ESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNEN------AKV------KGNSVCFLC 253
            :.|.|..|...:.:..|.||    |..|.|....::..||:      ||:      :|..|..:.
Zfish   165 QGYPTFARTLPSPLRVLFNV----LKFFRWANIGIVSSNEDIWIDTAAKLASALRNRGLPVGIVT 225

  Fly   254 LAAIHDTIEEHSVYQLGFDTSTWTKADITRMLKNVAMQSRIVIMCADPQSI---RQIMLTAEELN 315
            ....:||:.|:::..                :|| |...:::|||.....|   :|.....:..:
Zfish   226 SMGNNDTMLENTLMS----------------IKN-AGDIKVIIMCMHSVLIGGEQQATFLTKAYD 273

  Fly   316 M-IDSGEYVFINIELFSRVQYLTSQPWYDKNDTDL-NNERAQKAYTAMLTVTPKQPNDNEYTRVS 378
            | :.||.||||..:..     |.|.|:.:.....| ||.:..|||.|:||:|    .|::....:
Zfish   274 MGLASGRYVFIPYDTL-----LYSLPYINITYYPLQNNSKLSKAYDAVLTIT----LDSDIMTFN 329

  Fly   379 NEIKAIAAEKYNYTFSDNEP--ISAFVTSFFDGVLLYANALNESIREDPTMLTRPINGTDMVRRM 441
            ....  ||::........||  :|....:.::.:.|.|.:::.:.|..     |.::||::....
Zfish   330 EAFN--AAKQLGELMVTQEPEQVSPLFGTIYNSLYLLAKSMHNARRAG-----RWLSGTNLAYFT 387

  Fly   442 WNRSFTGITGNVTIDANGDRLSAYSLLDMNP-TTGRFEIVAHFLHNRLEFEANKEIHWAGDREEA 505
            .|.:|||...::..|..|:..:.|.:||... .|..:......:.:.|...|.:.||:.|  |..
Zfish   388 RNITFTGFNQDIQTDEQGNGQTNYVILDTEAWGTQLYRCFLVDMTSDLVLFAGRFIHFPG--ESP 450

  Fly   506 PPDRPICGY-DGALCPDNSLPGYAILSIVLGTMVVVMAVCFFFGYRHYIAEAEINSMSWKV--SL 567
            ||....|.: |.|:|.......|.|::.|:..::|:.::......|..|.:.::.....::  :|
Zfish   451 PPSDSRCWFEDNAICTGGVDIIYVIIAFVIVLIIVLGSIGLSLFIRRRIQQIQLIKGPNRILLTL 515

  Fly   568 EDVMFRDAAERGLRGSFHSLVKQSSQLTLMSEDMVSI----NGDRQIFIPVGMFRKSKVAIKPVE 628
            ||:.|.:.          .|.|:...|..:|:....|    .|||...:       :.:|....|
Zfish   516 EDLTFINP----------QLSKRKITLEDLSDSKSYIEEKSTGDRSRSV-------NSMATATHE 563

  Fly   629 VDNV---QG------LLTRSLMLELK--------RMKDLQHDHLVKFYGACLDQRRSFLLTEYCP 676
            ..||   :|      ..|.....|:|        :||||:::::..|.|...|.....::||:|.
Zfish   564 TSNVAVYEGDWVWLKKFTEGHFKEVKQSTTKIFTKMKDLRNENVNPFLGFFTDCEMFAIVTEHCS 628

  Fly   677 KGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNCVVDSRFVLKITDFG- 740
            :|||.|:|.|:..:|||||:.||:.|:::||::||..:. .||.|||.|||||.||||||||:|
Zfish   629 RGSLHDLLRNDDVKLDWMFKSSLVLDLIKGMKYLHHREF-PHGRLKSRNCVVDGRFVLKITDYGY 692

  Fly   741 ---LHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHNRPPEGTQKGDVYAFGIIVHEIT 802
               |.|.:..:..|..:           .|.|||||.|| :...|.:||.|||||:|.||:.|:.
Zfish   693 NEILETQKAPKETLPPE-----------DLFWTAPEHLR-DPESPRKGTYKGDVYSFAIILQEVV 745

  Fly   803 TRQGPFYLGRCAYEKSPQEIIELVKGYNPHRMQKP---FRPELEPNGDTKADINGIIRRCWAEDP 864
            .|..|:    |....||:|||..||        ||   .||.:.|: ....:...::::||:|.|
Zfish   746 VRGAPY----CMLGLSPEEIIRKVK--------KPPPMCRPTVAPD-QAPLECIQLMKQCWSEQP 797

  Fly   865 AERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQL 929
            ..||.|:.:....:..||..:| ||:|::|:.:|.|::|||:|:.|||::...||::.||||.::
Zfish   798 DRRPPFDQIFDQFKLINKGKKT-NIIDSMLRMLEQYSSNLEDLIRERTEELEVEKQRTEKLLSEM 861

  Fly   930 LPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDV 994
            ||.|||..|.:|..|..|.|||||||||||||||.||:.|.|::||..|||||:.||:::.:.||
Zfish   862 LPPSVAEALKTGASVEPEYFDQVTIYFSDIVGFTTISSLSDPIEVVDLLNDLYSLFDAVLGSHDV 926

  Fly   995 YKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVA 1059
            ||||||||||||.||||.:|||:||.|||.::|.:|.:|.:|::.|.||..:::|||:|:|.|||
Zfish   927 YKVETIGDAYMVASGLPKKNGNKHAAEIANMSLNILSSVGSFKMRHMPEVPVRIRIGIHSGPCVA 991

  Fly  1060 GVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGT-FVTTRRGFVPMKGKGEM 1123
            |||||.|||||||||||||||||||.|...:||::.:|.:.|..... :....||...:||||..
Zfish   992 GVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNISTVQILRSLNDGYKIDVRGKTELKGKGIE 1056

  Fly  1124 LTYWLEGEV----PRPN 1136
            .||||.|:.    |.||
Zfish  1057 ETYWLVGKANFTKPLPN 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596	69/311 (22%)
		PK_GC-A_B	589..883	CDD:270944	108/321 (34%)
		HNOBA	<890..938	CDD:462234	22/47 (47%)
		CYCc	917..1108	CDD:214485	113/191 (59%)
gucy2f	NP_571939.2	PBP1_sensory_GC_DEF-like	59..440	CDD:380594	69/311 (22%)
		PK_GC-2D	551..816	CDD:270945	101/297 (34%)
		HNOBA	<825..870	CDD:462234	21/44 (48%)
		CYCc	850..1042	CDD:214485	113/191 (59%)