Protein Alignment CG31183 and npr2

DIOPT Version :10

• Sequence 1: NP_650505.2
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: XP_009300100.2
• Gene: npr2 / 100331745
• ZFINID: ZDB-GENE-141030-2
• Length: 1048
• Species: Danio rerio
• Alignment Length: 1109
• Identity: 476/1109 - (42%)
• Similarity: 651/1109 - (58%)
• Gaps: 129/1109 - (11%)

  Fly    79 RLGARRQLVFVALLPSV-------ESDNKNDCIM-----------PKVLPVLELAIRHVQRMGFV 125
            ::|.|   ||:.||..:       |..|....:|           |:|||.:.:|...:|:.|.:
Zfish     6 KMGYR---VFIVLLTRMVVLECRAEKGNITVAVMLPENLKYSWASPRVLPAIRMAQEKIQKSGLL 67

  Fly   126 GG-----------------SHFDIQLISRDTFCSSKYGPIGFFEIYTQWPEVNAVFGLPCEYVLA 173
            .|                 |..:.|:|:.||            ::|.: |:  |..|..|.|.:|
Zfish    68 RGHTINLLNFSTEDSSGSCSENEAQIIAVDT------------KLYHK-PD--AFIGPGCTYSVA 117

  Fly   174 PISRYADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQ 238
            .:.|:|..|::|::|.||.|..|: |.|.:.|:.| .|.....||:.|..:...|||:..||:..
Zfish   118 SVGRFASHWKLPLITAGGPAYGFD-KWEEFKTIVR-TGPTTKKLGDFVNYLHGQFNWSSRALMIF 180

  Fly   239 NENAKVKGNSVCFLCLAAIHDTIEEHSVYQLGF---DTSTWTKADITRMLKNVAMQSRIVIMCAD 300
            :: .|.......||. ..|:..:.|.::..|.|   |..|:...|:...:|:   ..|||.:|..
Zfish   181 HD-LKQDDRPHYFLS-EGIYTVLREENITVLAFPYEDEQTYNYKDMITFIKD---NGRIVYICGP 240

  Fly   301 PQSIRQIMLTAEELNMIDSGEYVFINIELFSRVQYLTS---QPWYDKNDTDLNNERAQKAYTAML 362
            ..:..|||...|: .:....:|....:::|:  :.|:.   .||   ..:|:......|.:.::.
Zfish   241 LPTFFQIMKLFED-EVKSPEDYAIFYLDVFA--ESLSGDVPMPW---QGSDIQWNDPIKLFQSVF 299

  Fly   363 TVTPKQPNDNEYTRVSNEIKAIAAEKYNYTFSDNEP-ISAFVTS-FFDGVLLYANALNESIREDP 425
            .||.::|:..|||....|:...|.:.:|...   || :..|:.. |.||.:|||.||:|::.:..
Zfish   300 VVTYQEPDSPEYTAFRKELHKRAIQDFNVQL---EPSMMDFIAGCFHDGFVLYAKALSEALADGV 361

  Fly   426 TMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDM-NPTTGRFEIVAHFLHNRLE 489
            :.    .:|.::..||.||...|:||.|:||....|.:.:||..| |..:|::.||.|:
Zfish   362 SQ----NDGINITARMQNRRLWGVTGLVSIDQKNARFTDFSLWAMTNLKSGQYAIVGHY------ 416

  Fly   490 FEANKEIHWAGDR-----EEAPP-DRPICGYDGALCPDNSLPGYAILSIVLGTMVVVMAVCFFFG 548
            ...:|||.|:...     :..|| |.|.||:  :.|.::.||...|:::..|..:::..:..|..
Zfish   417 NGTSKEILWSPTEKIQWPKGCPPLDYPPCGF--SPCKEDHLPVLGIVAVGSGLALIIFGISSFLI 479

  Fly   549 YRHYIAEAEINSMSWKVSLEDVMFRDAAERGLRGSFHSLVKQSSQLTLMSE-----DMVSINGDR 608
            ||....|.|:..|.|::..|::.|...      ..:|.  :..|:|||...     .:::.:|..
Zfish   480 YRKLKLEKELAGMLWRIRWEELQFESP------NKYHK--RAGSRLTLSQRGSSYGSLITAHGKY 536

  Fly   609 QIFIPVGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFYGACLDQRRSFLLTE 673
            |:|...|.|:.:.||||.|....::  |||.::.|||.|:|:|.:||.:|.|||:|.....::||
Zfish   537 QLFAKTGYFKGNLVAIKHVNKKRIE--LTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTE 599

  Fly   674 YCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNCVVDSRFVLKITD 738
            |||:||||||||||...||||||.||::|||:||.:||:|.|.||||||||||||||||||||||
Zfish   600 YCPRGSLQDILENESINLDWMFRYSLINDIVKGMNYLHNSYIGSHGNLKSSNCVVDSRFVLKITD 664

  Fly   739 FGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHNRPPEGTQKGDVYAFGIIVHEITT 803
            :||.:.|       |...|.:|||.::|.|||||||| :....||:||||||||:||||:.||..
Zfish   665 YGLASFR-------SSCENEDSHALYAKKLWTAPELL-IYDRHPPQGTQKGDVYSFGIILQEIAL 721

  Fly   804 RQGPFYLGRCAYEKSPQEIIELVKGYNPHRMQKP-FRPELEPNGDTKADINGIIRRCWAEDPAER 867
            |.||||:.  ..:.||:|||:.|:     ..||| |||..: |.....::..::..||:||||||
Zfish   722 RNGPFYVE--GMDLSPKEIIQKVR-----NGQKPYFRPTTD-NSRHCEELTILMEGCWSEDPAER 778

  Fly   868 PDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLPQ 932
            |||:.:|..|.:|||:..| :|::|||.|||.||||||.|||||||.|.|||:|.|.||||:||.
Zfish   779 PDFSHIKVFIAKFNKEGST-SILNNLLSRMEQYANNLENLVEERTQAYLEEKRKAENLLYQILPH 842

  Fly   933 SVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDVYKV 997
            |||.||..|:.|.||.||.||||||||||||::||||||:|||..|||||||||:|::|||||||
Zfish   843 SVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKV 907

  Fly   998 ETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVV 1062
            ||||||||||||||:|||..||||||.::|||||.|..|:|.|||.|:|:||||:|||...||||
Zfish   908 ETIGDAYMVVSGLPVRNGKLHAREIAGMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVV 972

  Fly  1063 GLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYW 1127
            ||||||||||||||||||||||.||||:||:|..|||.|||||.|....||.|.|||||:|.|||
Zfish   973 GLKMPRYCLFGDTVNTASRMESTGEALRIHMSSATKEVLDEFGYFELQLRGDVEMKGKGKMRTYW 1037

  Fly  1128 LEGE 1131
            |.||
Zfish  1038 LLGE 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31183	NP_650505.2	PBP1_NPR-like	87..493	CDD:380596	116/449 (26%)
		PK_GC-A_B	589..883	CDD:270944	150/299 (50%)
		HNOBA	<890..938	CDD:462234	34/47 (72%)
		CYCc	917..1108	CDD:214485	144/190 (76%)
npr2	XP_009300100.2	None