Protein Alignment Hmt-1 and abcb7

DIOPT Version :9

• Sequence 1: NP_650503.1
• Gene: Hmt-1 / 41925
• FlyBaseID: FBgn0038376
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_694879.2
• Gene: abcb7 / 566515
• ZFINID: ZDB-GENE-050517-10
• Length: 743
• Species: Danio rerio
• Alignment Length: 601
• Identity: 264/601 - (43%)
• Similarity: 371/601 - (61%)
• Gaps: 23/601 - (3%)

  Fly   227 NGWRKLRTVFPYLWPKKNIALQIAVIVCIILLLAGRVIKLFLPIYRKKLVDS----------LTI 281
            |..:.|..:|.|:|||....|:..|::.:.||...::..:.:|...|..|||          |:.
Zfish   107 NSSKILGAMFTYVWPKDRPDLRARVVISLSLLAGAKITNVMVPFMFKYAVDSLNQMSGHMLNLSD 171

  Fly   282 APIVFRWDFVLIYVALSFLQGGG---TGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSL 343
            ||      ..::.:|.:.|.|.|   ||| .|||.||..::.:|.|.:.|.|...:|.|||.|.|
Zfish   172 AP------NTVVTMATAVLIGYGVSRTGS-ALFNELRNAVFGKVAQSSIRRIAKNVFLHLHNLDL 229

  Fly   344 RWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTILDLLVAVAYFVYAFNWWFGLIVFLTMFL 408
            .:||.|:||.:.:.:||||..|:.:|:.:||::.||:.::::......|.....|.|:...|:..
Zfish   230 GFHLSRQTGALSKAIDRGTRGISFVLSALVFNLGPTLFEMMLVSGILYYKCGGHFALVTLGTLSA 294

  Fly   409 YIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEF 473
            |.|.|:|:|:|||:::..||.||||....::|||||:|||||:..|.||.:.|...:..|:....
Zfish   295 YTAFTVAVTQWRTQFRIEMNKADNEAGNAAIDSLLNYETVKYFNNEKYEAERYDGFLKVYESSSL 359

  Fly   474 LSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVHHQTLTVGDFVLFSTYLMELYMPLNWFGTYYR 538
            .:..||.|||..|:.|..:||.|..:|....:: ..|:||||.|:.:..|.:|.:|||:.||.||
Zfish   360 KTTSTLAMLNFGQSAIFSVGLTAIMVLASKGIM-SGTMTVGDLVMVNGLLFQLSLPLNFLGTVYR 423

  Fly   539 AIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTA--GGGIEFSNVTFGYSPEKIVLRNVSFTVPA 601
            ..::..:||..:|.||..:.:|.:.....||:..  ...|.|.:|.|.|...:.||..|||.|||
Zfish   424 ETRQALIDMNTLFTLLSVDTKIKEKEMAPPLIVTPQEATIRFEDVYFEYLEGQKVLNGVSFEVPA 488

  Fly   602 GKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQDTVLFNNTI 666
            ||.|||||.||:|||||:|||||||:.|.|.|.|.||||:.|..:|||||:||||||.|||:|||
Zfish   489 GKKVAIVGGSGSGKSTIVRLLFRFYEPQQGNIYIAGQNIRDVGLESLRKAVGVVPQDAVLFHNTI 553

  Fly   667 FYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVAIARTLLKAP 731
            |||:.|..:.|:.|.||..||.|.||:.||..|.||:|:||||||:|||||||||||||.:||.|
Zfish   554 FYNLMYGNINATAEDVYRVARLAGIHDAILKMPHKYDTQVGERGLKLSGGEKQRVAIARAILKNP 618

  Fly   732 IIVLLDEATSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGSIAERGRHEE 796
            .|:|.|||||:||:.||.||..::..:..:||::.:|||||||:.||||:||.||.:||||.|:.
Zfish   619 PILLYDEATSSLDSVTEENILTSMKEMVKDRTSVFIAHRLSTIVDADEIIVLNQGKVAERGNHQT 683

  Fly   797 LVLREDGIYADMWQQQ 812
            |:.....:||::|..|
Zfish   684 LLDTPGSLYANLWNTQ 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmt-1	NP_650503.1	MTABC_N	3..241	CDD:292803	4/13 (31%)
		ABC_membrane	255..530	CDD:279056	99/287 (34%)
		ATM1	314..811	CDD:227590	234/498 (47%)
		ABCC_ATM1_transporter	576..812	CDD:213220	140/235 (60%)
abcb7	XP_694879.2	ABC_membrane	133..415	CDD:279056	99/289 (34%)
		ATM1	200..696	CDD:227590	233/496 (47%)
		ABCC_ATM1_transporter	463..699	CDD:213220	140/235 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248727at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820