Protein Alignment Hmt-1 and atm1

DIOPT Version :9

• Sequence 1: NP_650503.1
• Gene: Hmt-1 / 41925
• FlyBaseID: FBgn0038376
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_594288.2
• Gene: atm1 / 2542779
• PomBaseID: SPAC15A10.01
• Length: 693
• Species: Schizosaccharomyces pombe
• Alignment Length: 652
• Identity: 247/652 - (37%)
• Similarity: 369/652 - (56%)
• Gaps: 57/652 - (8%)

  Fly   200 PYNPHQRLDNDTANESQGNVQTGSAFRNGWRKLRTVFPYLWPKKNIALQIAVIVCIILLLAGRVI 264
            |.|...:|.:|..::.  || ||...      ::.:..|:|||....|::.|:..:.||:|.:::
pombe    77 PLNTSVKLASDVPDDK--NV-TGQMI------VKDMLQYIWPKGKTNLKVRVVSALALLVAAKIL 132

  Fly   265 KLFLPIYRKKLVDSL-------------TIAPIVFRWDFVLIYVALSFLQGGGTGSMGLFNNLRT 316
            .:.:|.|.|.::|::             |:..:|..:.|..|:..             :|..||.
pombe   133 NVQVPFYFKSIIDTMNTTLVQEVGALWSTVGAVVLGYGFARIFST-------------VFQELRN 184

  Fly   317 FLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTIL 381
            .::..|.|...|.:...:::||..|.:.:||.::||.:.|.|||||..|:.:|:.:|..|.|..|
pombe   185 SVFAIVSQSAIRSVSSNVYQHLLNLDMNFHLSKQTGSITRAMDRGTKGISFILSSMVLHIIPITL 249

  Fly   382 DLLVAVAYFVYAFNWWFGLIVFLTMFLYIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFE 446
            ::.:......|.:...|..|...|:.||...|:..|.|||.::|:.|.||::..|.:::||:|:|
pombe   250 EIAMVSGILTYKYGPSFSAIAATTVALYALFTVRTTSWRTVFRRQANAADSKASAAAIESLINYE 314

  Fly   447 TVKYYGAEHYEVDCYREAILKYQKEEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYL---VVHH 508
            .||.:..|.||:..|.:.:..|:|.......:|..||:.|.||....|    .|.:|:   .:..
pombe   315 AVKTFNNESYEMSRYEKHLSAYEKANVKVASSLAFLNSGQAIIFSTAL----TLMMYMGCRGIVT 375

  Fly   509 QTLTVGDFVLFSTYLMELYMPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAG 573
            ..|||||.|:.:..:.:|.:|||:.|:.||.:::.|.|||.:|.|.:...::.:||....|:..|
pombe   376 SNLTVGDLVMINQLVFQLSIPLNFLGSVYREMRQAFTDMEQLFSLKRINIQVKEAPDARDLVLKG 440

  Fly   574 GGIEFSNVTFGYSPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQ 638
            |.|:|.||.|.|:|.:.:|...||.:|||..||.||.||.|||||:||||||||..:|.||||.|
pombe   441 GSIQFDNVHFSYNPNRPILNGCSFNIPAGAKVAFVGASGCGKSTILRLLFRFYDTDSGKILIDNQ 505

  Fly   639 NIKLVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYE 703
            .:..:...|||||||||||||.|||:||.|||.|....||::.:.|||:.|.||:.|..|||.|:
pombe   506 RLDQITLNSLRKAIGVVPQDTPLFNDTILYNIGYGNPKASNDEIVEAAKKAKIHDIIESFPEGYQ 570

  Fly   704 TKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTE----RNIQAALARVCANRTT 764
            ||||||||.:|||||||:|::|.|||.|.|:..|||||||||:||    |||...:..  :::|:
pombe   571 TKVGERGLMISGGEKQRLAVSRLLLKNPEILFFDEATSALDTNTERALLRNINDLIKG--SHKTS 633

  Fly   765 IIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGIYADMWQQQLKNLDAEQSGGSDN--G 827
            :.:||||.||...|.|.||::|.:.|:|.||:| :.::.:|..||..|      |...|..|  |
pombe   634 VFIAHRLRTIKDCDIIFVLEKGRVVEQGSHEQL-MAKNSVYTSMWHSQ------ESPFGESNKSG 691

  Fly   828 DA 829
            ||
pombe   692 DA 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmt-1	NP_650503.1	MTABC_N	3..241	CDD:292803	9/40 (23%)
		ABC_membrane	255..530	CDD:279056	80/290 (28%)
		ATM1	314..811	CDD:227590	214/503 (43%)
		ABCC_ATM1_transporter	576..812	CDD:213220	129/239 (54%)
atm1	NP_594288.2	ABC_membrane	123..397	CDD:279056	80/290 (28%)
		ATM1	182..677	CDD:227590	212/501 (42%)
		ABCC_ATM1_transporter	443..680	CDD:213220	129/239 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810