Protein Alignment Hmt-1 and pgp-8

DIOPT Version :9

• Sequence 1: NP_650503.1
• Gene: Hmt-1 / 41925
• FlyBaseID: FBgn0038376
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_509811.2
• Gene: pgp-8 / 181277
• WormBaseID: WBGene00004002
• Length: 1243
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 179/548 - (32%)
• Similarity: 292/548 - (53%)
• Gaps: 73/548 - (13%)

  Fly   330 IEIELFRHL---------HQLSLRWHLQRK---------TGEVLRV----MDRGTDSINNLLNYI 372
            |:..||:::         |:..||  |.:|         ||.:..|    ::|..::.|..:.:|
 Worm   116 IQFSLFKYIGDNTTYRLRHKFILR--LLKKDAKYFDTISTGYLSTVLNDNLERFREAFNEKIAFI 178

  Fly   373 V-FSIAPTILDLLVAVAYFV------YAFNWWFGLIVFLTMFLYIASTIAITEWRTKYQRRMNLA 430
            : ||   |...:..|:|::.      |...:.||:::         |.:..:....|...:.::.
 Worm   179 ICFS---TDFAIGTALAFYTSWTLASYGSVFAFGIVI---------SGLLNSTSMMKSNEKQSMH 231

  Fly   431 DNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEFLSMLTLNMLNTAQNI--ILCLG 493
            .:...|.:..:|.:|:||.....:..|::.| .|.|| :.|:|.|.... .|.|::.:  ..| .
 Worm   232 YSNAGAIAFQALCSFKTVISLNGQTQELEKY-SAELK-EGEKFGSRRAF-FLATSRGLSHFFC-N 292

  Fly   494 LLAGSLLCVYL-VVHHQTL------TVGDFVLFSTY-LMELYMPLNWFGTYYRAIQKNFVDMENM 550
            .|.|::|.|.. :::::|:      |:..::|||.: |.|.::.:::.   ..||.    ....:
 Worm   293 ALNGTILYVGADLIYNKTMNTVAIVTLFHYMLFSAFSLGEAFLHISYL---LNAIN----SATPI 350

  Fly   551 FDLLKEEEEIV----DAPGCSPLLTAGGGIEFSNVTFGY--SPEKIVLRNVSFTVPAGKTVAIVG 609
            ||:|..:::::    |........|..|.:.|:||.|.|  .|:..:||.:||.|..|:.:|:||
 Worm   351 FDVLTSDDDMIENNQDNEQTDSNKTIQGMLSFNNVKFAYPSRPDVDILRGISFDVKQGECIALVG 415

  Fly   610 PSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAK 674
            .||:|||||::||..||::|:|.|.|...::..:..:.||.|||||.|:.||||.||..||.:..
 Worm   416 ASGSGKSTIVQLLLHFYNIQSGTIKIGDSHLHDINLKQLRNAIGVVSQEPVLFNTTIEENIRFGN 480

  Fly   675 LGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEA 739
            ..|:...:|||.|.|:.::.:....:..:|.|||||.:||||:|||:||||.|:|.|.|:|||||
 Worm   481 PNATSSEIYEALRKANAYDFVCNIKDGLKTIVGERGAQLSGGQKQRIAIARVLVKNPAILLLDEA 545

  Fly   740 TSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGI 804
            |||||:.:||.:|.||.:....|||||:|||||||.|.|:|:|:..|.|||.|.||||: ..|..
 Worm   546 TSALDSASERAVQLALKKASEGRTTIIIAHRLSTIRHCDKIMVMSNGKIAEVGSHEELI-SMDRE 609

  Fly   805 YADMWQQQLKNLDAEQSGGSDNGDASAE 832
            |:::.:.|.  .|::......||..:.|
 Worm   610 YSNLVRAQF--FDSQSVEEDINGQGAEE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmt-1	NP_650503.1	MTABC_N	3..241	CDD:292803
		ABC_membrane	255..530	CDD:279056	51/238 (21%)
		ATM1	314..811	CDD:227590	174/525 (33%)
		ABCC_ATM1_transporter	576..812	CDD:213220	115/237 (49%)
pgp-8	NP_509811.2	PTZ00265	29..1241	CDD:240339	179/548 (33%)
		ABC_membrane	44..326	CDD:294371	47/227 (21%)
		ABC_MTABC3_MDL1_MDL2	382..617	CDD:213216	115/235 (49%)
		ABC_membrane	685..953	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1005..1240	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248727at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920