Protein Alignment Hmt-1 and abcb6b

DIOPT Version :9

• Sequence 1: NP_650503.1
• Gene: Hmt-1 / 41925
• FlyBaseID: FBgn0038376
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_021334538.1
• Gene: abcb6b / 100004801
• ZFINID: ZDB-GENE-070912-584
• Length: 683
• Species: Danio rerio
• Alignment Length: 619
• Identity: 363/619 - (58%)
• Similarity: 465/619 - (75%)
• Gaps: 14/619 - (2%)

  Fly   211 TANESQGNVQTGSAFRNGW----RKLRTVFPYLWPKKNIALQIAVIVCIILLLAGRVIKLFLPIY 271
            |.:|..|||:..|. |:.|    ||:..:.||:||:.::.||:.||:|:.||...|||.:|:|||
Zfish    63 TEHERDGNVEQISR-RSAWQDFRRKVCLLVPYMWPRGSVWLQVLVILCVGLLGLERVINVFVPIY 126

  Fly   272 RKKLVDSLTIAPIVFRWD----FVLIYVALSFLQGGGTGSMGLFNNLRTFLWIRVQQYTTREIEI 332
            .:.:|:.|:   .:..|.    .|.:||.|.|.||||.|:.|..:|||:|||..|||||:|.:::
Zfish   127 SRNIVNQLS---AMENWRTLAITVCVYVLLKFFQGGGVGTSGFVSNLRSFLWTHVQQYTSRVVQV 188

  Fly   333 ELFRHLHQLSLRWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTILDLLVAVAYFVYAFNWW 397
            .||.|||.|||||||.|:||:|||.:||||.|:||||:||||||.|||.|:::|:.|||..|:.|
Zfish   189 RLFAHLHGLSLRWHLGRRTGDVLRSIDRGTSSVNNLLSYIVFSIVPTIADIVIAIIYFVTYFSAW 253

  Fly   398 FGLIVFLTMFLYIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYR 462
            ||||||:.||||:..||.||||||||:|.||..||..::::|||||||||||||.:|.:||..:.
Zfish   254 FGLIVFICMFLYLTLTIIITEWRTKYRREMNTQDNNAKSKAVDSLLNFETVKYYNSEGFEVRRFE 318

  Fly   463 EAILKYQKEEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVHHQTLTVGDFVLFSTYLMELY 527
            :||||||..|:.:..:|.:||..||:|:.||||||||||.|.|...: ..|||:|||.||:::||
Zfish   319 DAILKYQACEWKTNASLALLNQTQNLIIGLGLLAGSLLCAYYVTVDK-FQVGDYVLFGTYIVQLY 382

  Fly   528 MPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGGIEFSNVTFGYSPEKIVL 592
            .||||||||||.||..|||||:|||||.||:|:.|......|....|.::|.||.|.|:..|.:|
Zfish   383 TPLNWFGTYYRMIQSAFVDMESMFDLLTEEKEVKDTVNAGDLSFTKGRVDFKNVCFSYTAGKEIL 447

  Fly   593 RNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQ 657
            .:|||||..|:|.|:|||||:|||||:||||||||||:|.||||||:|..|:|.|||..||||||
Zfish   448 SDVSFTVMPGQTFALVGPSGSGKSTIIRLLFRFYDVQSGCILIDGQDIAKVRQNSLRSYIGVVPQ 512

  Fly   658 DTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVA 722
            ||||||:.|..||.|.::.|||:.|.|||.|||||::||..|:.|:|:||||||:||||||||||
Zfish   513 DTVLFNDNIRENIRYGRISASDQEVEEAAVAADIHDKILSLPDGYDTEVGERGLKLSGGEKQRVA 577

  Fly   723 IARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGS 787
            ||||:||:|.|:||||||||||:.|||||||:||:||||.||::||||||||:.:|:||||..|.
Zfish   578 IARTILKSPRIILLDEATSALDSQTERNIQASLAKVCANHTTLVVAHRLSTIVSSDQILVLHDGR 642

  Fly   788 IAERGRHEELVLREDGIYADMWQQQLKNLDAEQS 821
            |||:|||||| |.:.|:||.||.:|.:..::|.|
Zfish   643 IAEQGRHEEL-LAKGGLYAAMWLKQQQTPESEVS 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmt-1	NP_650503.1	MTABC_N	3..241	CDD:292803	12/33 (36%)
		ABC_membrane	255..530	CDD:279056	154/278 (55%)
		ATM1	314..811	CDD:227590	317/496 (64%)
		ABCC_ATM1_transporter	576..812	CDD:213220	159/235 (68%)
abcb6b	XP_021334538.1	MTABC_N	<64..96	CDD:318426	11/32 (34%)
		ATM1	170..665	CDD:227590	317/496 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595309
Domainoid	1	1.000	314	1.000	Domainoid score	I1261
eggNOG	1	0.900	-	-		E1_COG5265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	837	1.000	Inparanoid score	I431
OMA	1	1.010	-	-		QHG54509
OrthoDB	1	1.010	-	-		D248727at2759
OrthoFinder	1	1.000	-	-		FOG0004593
OrthoInspector	1	1.000	-	-		otm25915
orthoMCL	1	0.900	-	-		OOG6_100761
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3271
SonicParanoid	1	1.000	-	-		X3206
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.840