DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4546 and Ckmt2

DIOPT Version :9

Sequence 1:	NP_650501.1	Gene:	CG4546 / 41922	FlyBaseID:	FBgn0038373	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001121124.1	Gene:	Ckmt2 / 688698	RGDID:	61977	Length:	419	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	133/359 - (37%)
Similarity:	200/359 - (55%)	Gaps:	27/359 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LRKY-------LTPELLEEYMLVTTPAPVDAYLYD-CAVSGFEHHDAP----VGIFAADADSYDV 168
            |||:       |||.:..:.....||:   .|..| |..:|.::...|    ||:.|.|.:||:|
  Rat    57 LRKHNNCMAECLTPTIYAKLRNKMTPS---GYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEV 118

  Fly   169 FNKLFDPIIKDYHGQMDNENDVLQKDPDFGNVDEIENLDPERKYILSARIRLARNIEGLPFFPKL 233
            |..||||:||..|...|..   :.|.|...:..:|.:...:.:|:||:|:|..|:|.||...|..
  Rat   119 FADLFDPVIKLRHNGYDPR---VMKHPTDLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPAC 180

  Fly   234 TEKQFIEVEEKVRSATETMDGELIGSYLTMADIDAETQAEMVKRHILFQRG-DEKLTTAGCYRFW 297
            :..:..|||....:|.|.:.|:|.|.|..::::..:.|..::..|.||.:. ...||.||..|.|
  Rat   181 SRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDW 245

  Fly   298 PTGRGVYHNPAETFLIWVNRQDHVHIMSMAQCGDLGDVYNRLVNGLTELEKTL-----AFARHPR 357
            |..||::||..:|||||:|.:||..::||.:.|::..|:.|...||.|:|:.:     .|..:.|
  Rat   246 PDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNER 310

  Fly   358 YGNLTACPTNLGTTLRASVHIRLPLLSKDPDRLLALAEEQQLQVRGTDGGELSTVEDGVMDISNK 422
            .|.:..||:||||.|||.||:|:|.||||| |...:.|..:||.|||.|.:.:.|.| |.||||.
  Rat   311 LGYILTCPSNLGTGLRAGVHVRIPKLSKDP-RFSKILENLRLQKRGTGGVDTAAVAD-VYDISNI 373

  Fly   423 RKLGFTEFELVKTLQDGVVTLINAEEELEISGQE 456
            .::|.:|.|||:.:.|||..|::.|::|| .||:
  Rat   374 DRIGRSEVELVQIVIDGVNYLVDCEKKLE-RGQD 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4546	NP_650501.1	arginine_kinase_like	89..450	CDD:153079	129/351 (37%)
Ckmt2	NP_001121124.1	Cardiolipin-binding	40..64		3/6 (50%)
Ckmt2	NP_001121124.1	creatine_kinase_like	50..407	CDD:153076	133/359 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3004
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2802
OMA	1	1.010	-	-		QHG58958
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm9032
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.980