Protein Alignment cv-d and apoba

DIOPT Version :9

• Sequence 1: NP_732076.1
• Gene: cv-d / 41921
• FlyBaseID: FBgn0265048
• Length: 1470
• Species: Drosophila melanogaster
• Sequence 2: XP_694827.7
• Gene: apoba / 566465
• ZFINID: ZDB-GENE-070702-4
• Length: 4418
• Species: Danio rerio
• Alignment Length: 1682
• Identity: 316/1682 - (18%)
• Similarity: 564/1682 - (33%)
• Gaps: 550/1682 - (32%)

  Fly    29 KQMLYEYEG---NVLVGAKPQDEGH--------QAPPTTGWIVRGKLTLQRQSELVLAAALVIDD 82
            ::.:|:|..   |.:.|......|.        :.|.|..:::       |.:|.||:...|||
Zfish    43 RKYVYQYTAESKNGVTGTANLKNGPKISCQVEIEVPQTCSFVL-------RTTECVLSEVSVID- 99

  Fly    83 VTLNNSGEKFLQNKEMY---PPYKPFKIALTK-------DGAISHVVFKEGD-PIWSMNFKRAIA 136
                      .|.:.:|   ...:.|:.|:.|       |...|..::.|.| |...:|.||.|.
Zfish   100 ----------AQGQPVYRQAAGAEAFQAAMEKNTLNFVVDQVTSVSIYPEEDEPENILNIKRGII 154

  Fly   137 SVLQFQMKSSGAFVVDE------LGIHGTCRTEYFVSNRTNY-ISIRKTPEVKTCKPYS-EAVHT 193
            |.|...       |::|      ..|||.|:||..|::|.:. |.:....::..|..:| .::.|
Zfish   155 SALLVP-------VLEEEHNERMSTIHGICKTEVTVNSRKDIDIDVSVVRDLSDCSHFSPHSLST 212

  Fly   194 TRSNVPP-------------NTC--EFDHQKSVIIGNEAIYGMSPHNETGYYLSMAHAKGTTLIH 243
            :..::.|             .||  :||:::                           |..|
Zfish   213 SPLSLMPGLNGLFSKLIRSTQTCNYQFDNRR---------------------------KHMT--- 247

  Fly   244 TFESTGEAQFINSELLLNFLNETPIDNPIDIETSMAAEPSNLELQRLDPNDPTGGRSPQQQETLI 308
                  |||.....|.:.|.:|.......:::.|:..:.|.....|....|
Zfish   248 ------EAQCTEKHLFIPFSHEGQYGISSEVKQSLTLQDSVKINNRYFNKD-------------- 292

  Fly   309 AQAGTLLDSLAEALETTEFKFSEPYDSTLSDVIKLLSEMDFDSLTKLYREVDIGTSYRQETIRNI 373
                   |:|.:.|...|.:...|..|. .||:..:.|:           :.:.:|.:.:...::
Zfish   293 -------DTLEKKLFIEEVEDKHPVQSK-DDVLATMKEL-----------ITLSSSGKSQQRASL 338

  Fly   374 FHEIIPRIG--------------TKASVFLTHHLVLNKLTKPQIAVQLLIPMPFHIFELSAELV- 423
            ||:::..:.              .|.|.:||...:....|....:..:.|...|...:...:.:
Zfish   339 FHKLVSEVRGLKNETLSGAADEMMKFSEWLTWQTLFQCGTDECTSAIMQILRTFDEADREVDAIV 403

  Fly   424 -----------QKCEDFLNIGPDRPDVRQAAILSFATLIHNVYVAKGIDKEKFEEYVQKYFNAYL 477
                       |:..|.|::...:|.  :..:.:.|..:..:...:.....:.:| |.|:....|
Zfish   404 YALSLLPQSSPQRLRDMLSMAQSKPS--KPIMYALANTVKQLPQDQATSTPEVKE-VAKFMEFML 465

  Fly   478 SD--RDFDQKML----------YLQGLNNLQLGNVANYLEPIVQDPNEHEDLKFQAAWTTLALAD 530
            .|  .|.|...|          |::|..:|: .:|.|.::. ...|...:....||.......:|
Zfish   466 GDCSGDEDSTFLTLRVIGVMGKYMEGFPSLK-SSVLNCMKQ-AYAPLPVQKAAIQAFRLMEMDSD 528

  Fly   531 RRAERIYEVYWPIFESRNASLELRVAAVTLLLISNPTAARLISIHRIIQSETDPHMINYYRTTVT 595
            .|:..|.:     :::..|..:.|:||. |:|:.||..|.  ::.|.::||.:..:.::..:.:.
Zfish   529 VRSALIQQ-----YQNVEAPAQKRIAAY-LMLMRNPEVAE--NVLRTLKSEQNEQVKSFVSSHIA 585

  Fly   596 SISETTYPCYQHLRRLLSYMHRHLPQKPESRYWVTGNYIFDYRD-SKFGIGAMLQVFLVGD---- 655
            :|.|:..|   :|.....|:.:.          |.|:..|...| :|.......:|.|||.
Zfish   586 NILESENP---NLSIAKDYILKA----------VQGDVSFPPMDFTKLSRNYKTEVPLVGSVESN 637

  Fly   656 ---------PKSDMPVVAFFKFDTEALGKFTGQLALYIKARGL--------------PDTILNKM 697
                     |:..|.......|:.|.       |.:.::..||              ||||...|
Zfish   638 VIFDSANYMPREVMLATTLDNFNPEI-------LEIGLEGEGLEPVIEVLFGENGFFPDTISKAM 695

  Fly   698 QSRNGSDPFTFKSI----------KALLAMLQAPIINSKDLHLEFILQMEGK------------- 739
            ...|...|...|.:          :.:...:...|:.|.:   |:|.:.:.:
Zfish   696 YWVNDKIPHPVKRVLEKWISPLNGERMKRQVPQDIMKSME---EYISEFKNRLEQVEDAPKGLAY 757

  Fly   740 -----TVLSYYLNQRMFRQLTYDNI---------LERMQQIIRTDSHINMQTVRWPFMNR-YTVP 789
                 |.|.|.....:.....|.|:         |..|.::|  .|..|...|.:.|::: :|:|
Zfish   758 LRLFGTELGYLKTSDLKHVTQYINLCAETFKSTSLNFMGKLI--SSLENEFFVHYMFLDKAFTLP 820

  Fly   790 TVLGTSSDVLLQTTVLTSLRGNITEQRNSPITKHTLEIDARYSSYASVRSRSYNPFLNLDHEINR 854
            |..|....:.|...:....:|.:|..|                   .::..|:.|.:.:  |...
Zfish   821 TSAGFPLKLTLSGVLAPGAKGGLTIDR-------------------MMQQLSFMPSVGV--EFIT 864

  Fly   855 EQGFLIYIP----FSSELHLN---ESGSKCR--------RYSFSRPQNLTSG------LSFKSRA 898
            :.|  :|||    ...|.|.|   ||....|        :.|...|    ||      :|.|..:
Zfish   865 QMG--VYIPEFVVAGIETHTNLYHESAVNARVTLSDSQIKLSIPAP----SGNIQLFSVSNKILS 923

  Fly   899 VTKTRGLITKTAAAPFEEIM-------VPEGRNDVVQL-FS----------YPMTD---LGVRLS 942
            ||.|:   ||...:..|:.:       :..|.|....| :|          ||:|.   |.:.|.
Zfish   924 VTSTQ---TKIVPSMVEDRIDSTECNRIFPGMNYCTILRYSNASSTNNAPYYPLTGETRLALELQ 985

  Fly   943 MTTNLNE---LIKYRGMLLKSEFTENGFSGNMVVNALMYIFGF-----TQLSSIHLGHDRNFTML 999
            .|..:.|   .|.|  .||:     .|..|...|:::..:...     |:.::: :.::||.::|
Zfish   986 PTGEVREYTATISY--ALLR-----EGKEGRQKVDSVKIVLKAEGAEPTEATAV-VKYNRNRSIL 1042

  Fly  1000 MYNEKNTRIE-GNFCAEDVLK----TSDMKGKQI-GLTLEHTD----------HMNENHAADALH 1048
                 .|.:: .::..|..:|    .::.|||:: |:|::.|:          |.......|.|.
Zfish  1043 -----TTDLQIPDYDLEAGIKLAVTDTNAKGKKMRGITIDVTNRDIPQLSIVGHARLESMRDGLI 1102

  Fly  1049 RWNITLDVLASTKSNWFKLTGQVQRNSKDDEDDWKACTKLTYEPLVFTKRPHTLNGDVVFGLATE 1113
            ...:::..|....|    .|..:::|                            || :|..|.|
Zfish  1103 ELQMSVPALQMDTS----ATATLKKN----------------------------NG-LVLQLET- 1133

  Fly  1114 ESECPEKGSTVQFAARAGPSEHARAFLRSD--KISLTDTDFCPKEVLKFSPIPTSRYCKRSNFEN 1176
            ....||. ::||           :|.||.|  |:.:........||.|..|          |.|.
Zfish  1134 AFNMPET-TSVQ-----------KAILRYDNNKVEIEMKSDINSEVEKLFP----------NMEE 1176

  Fly  1177 FTSITQYDMDLKFDNMPAWFELWSNRLDHLVS-ALSA-----DKV--DSLHMSQEINISMQTPQD 1233
            :.|..|..:|...|......::   :|.|:|| .|.|     ||:  .|..:..:.| ...||:
Zfish  1177 YRSQLQASIDEILDKKVTKTDM---KLRHIVSKGLEAVNIWLDKIAAGSSFVDVQRN-KRSTPE- 1236

  Fly  1234 QFRLAVEVNGVKWRFHQIPFFYKLDSKFDASHELTFDSG-LKRSCSVINGIVNTFDDYLINLREI 1297
               |.:.         .:|  .||..|.||.....|:.| :..|..::.|..::        .|:
Zfish  1237 ---LILP---------SLP--EKLYLKSDALLRYQFNKGRISISLPLLLGGKSS--------AEL 1279

  Fly  1298 AVRPDCLTLLVADCSPLPQIAVFVTPSPVQGLSTNYGLRVHIGQNYFNFRA----RTDNSSLPTD 1358
            .: |..||        ||||.:     |:.||        .:.:|.:....    ||...|||
Zfish  1280 DI-PPTLT--------LPQIQI-----PLLGL--------EVPENSYKIPTFTIPRTLEFSLP-- 1320

  Fly  1359 EPVLIYLNQDQTPHNVRKKPYQW---------PIETSDYDFRVE------LNEQNILIVECTQLS 1408
                 .|...:....:....|:|         .::..:|..:.:      |...:..|.....:|
Zfish  1321 -----MLGVAELSAKMNSNFYEWEGSILGGNNTVDVPNYIAKYKIMASCPLTPLSYKIEGMGMIS 1380

  Fly  1409 STIQFDLYNILNFEIYGVYKH----------QMCGLCSKPLNRMQNYTICELEANTP 1455
            .|:.    :.|.:.:.|...|          :...|..| :|...||   .|||::|
Zfish  1381 GTVD----DTLKYLVNGSINHCLLDASISFFETMSLADK-INGRTNY---RLEASSP 1429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-d	NP_732076.1	LPD_N	28..589	CDD:214755	116/642 (18%)
		DUF1943	632..>813	CDD:286281	44/246 (18%)
		VWD	1277..1435	CDD:295339	29/186 (16%)
apoba	XP_694827.7	Vitellogenin_N	39..584	CDD:331790	116/647 (18%)
		DUF1943	619..917	CDD:312626	61/336 (18%)
		DUF1081	939..1044	CDD:310803	22/117 (19%)
		NBD94	<2026..>2549	CDD:330409

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810