Protein Alignment cv-d and vtg6

DIOPT Version :9

• Sequence 1: NP_732076.1
• Gene: cv-d / 41921
• FlyBaseID: FBgn0265048
• Length: 1470
• Species: Drosophila melanogaster
• Sequence 2: NP_001116082.3
• Gene: vtg6 / 559229
• ZFINID: ZDB-GENE-001201-5
• Length: 1374
• Species: Danio rerio
• Alignment Length: 1539
• Identity: 279/1539 - (18%)
• Similarity: 508/1539 - (33%)
• Gaps: 456/1539 - (29%)

  Fly     7 SVFVYLFLIFDAGHAFSII---GLNKQMLYEYEGNVLVGAKPQDEGHQAPPTTGWIVRGKLTLQR 68
            :|.:.|.:...|...|:::   ..:|..:|:||. :|:|..||:...:|    |..|..|:.|..
Zfish    14 AVVLALTVALVASQQFNLVPEFAHDKTYVYKYEA-LLLGGLPQEGLARA----GIKVSSKVRLSA 73

  Fly    69 QSELVLAAALVIDDVTLNNSGEKFLQNKEMYPPYKPFKIALT-----------KDGAISHVVFKE 122
            .:|......| :|.:....:|   ...|:.:.|......||.           .:|.:..|....
Zfish    74 MTENTYLMKL-MDPLLYEYAG---TWPKDSFVPATKLTSALAAQLQIPIKFEYANGVVGKVFAPA 134

  Fly   123 GDPIWSMNFKRAIASVLQFQM-KSSGAFVVDELGIHGTCRTEYFVSN--RTNYISIRKTPEVKTC 184
            |.....||..|.|.::||..: |:...:.:.|.|..|.|||.|.::.  :||:|.:.|:.::..|
Zfish   135 GVSPTVMNLHRGILNILQLNLKKTQNIYELQEAGAQGVCRTHYVINEDPKTNHIIVTKSKDLSHC 199

  Fly   185 K---------PYSE--AVHTTRSNVPPNTCEFDH-----QKSVIIGN---EAIYGMSPHNETGYY 230
            :         .|:|  |..|.|......|..:::     ....:|..   |.:|..||.||. :.
Zfish   200 QERIMKDVGLAYTERCAECTKRVKSLIETATYNYIMKPADNGALIAEATVEEVYQFSPFNEI-HG 263

  Fly   231 LSMAHAKGTTLIHTFEST------------GEAQF-INSELLLNFLNETPIDNPIDIETSMAAEP 282
            .:|..||.|......|.|            |..|: ..||:|     :|||
Zfish   264 AAMMEAKQTLAFVEIEKTPVVPIKADYMPRGSLQYEFASEIL-----QTPI-------------- 309

  Fly   283 SNLELQRLDPNDPTGGRSPQQQETLIAQAGTLLDSLAE-----ALETTEFKFSEPYDSTLSDVIK 342
               :|.::..       :|       ||...:|..|.|     ..:...|||.:        :::
Zfish   310 ---QLMKIKD-------AP-------AQIVEVLKHLVENNKDMVHDDAPFKFVQ--------LVQ 349

  Fly   343 LLSEMDFDSLTKLYREVDIGTSYRQETIRNIFHEIIPRIGTKASV-FLTHHLVLNKLTKPQ---- 402
            ||..:..|.:..::.:......||:..:     :.:|.:||...: |:....:..:.|.|:
Zfish   350 LLRVVTLDKIEAIWSQFKDKPVYRRWLL-----DALPAVGTPVIIKFIKEKFLAGEFTTPEFIQT 409

  Fly   403 --IAVQLLIPMPFHIFELSAELVQKCEDFLNIGPDRPDVRQAAILSFATLIHNVYVAKGIDKEKF 465
              ||:| ::.......:::|.|... |.|::|    |.:|:..:|.:.:||....||......:.
Zfish   410 LVIALQ-MVTADLETIQMTASLAMH-EKFVSI----PALREVVMLGYGSLIAKHCVAVPTCPAEL 468

  Fly   466 EEYVQKYFNAYLSDRDFDQKMLYLQGLNNL--------------QLGNVANYLEPIVQDPNEHED 516
            ...:.:.....:|..|..:..|.|:.:.|.              .|...||.|...||
Zfish   469 LRPIHETATEAISKNDIPEITLALKVMGNAGHPSSLKPIMKLLPGLRTAANALPVRVQ------- 526

  Fly   517 LKFQAAWTTLALADRRAERIYEVYWPIFESRNASLELRVAAVTLLLISNPTAARLISIHRIIQSE 581
              ..|......:|.:..:.:..|...:...|....|:|:.|..:|..:.|:.|.:.|:...:::|
Zfish   527 --VDAILALRNIAKKEPKLVQPVALQLVLDRALHPEVRMVACIVLFETEPSVALISSLAGALRTE 589

  Fly   582 TDPHMINYYRTTVTSISETTYPCYQHLRRLLSYMHRHLPQKPES-RYWVTGNYIFDYRDSKFGIG 645
            .:.|:.::..:.:.|::..|.|...::....:...:.:..|.:. .|..:..:..||..:...||
Zfish   590 PNMHVASFAYSHIKSLTRITAPDMAYVAGAANVAIKLMNCKLDRLNYRYSRAFQMDYYYTPLMIG 654

  Fly   646 AMLQVFLVGDPKSDMPVVAFFKFDTEALGKFTGQLALYIKARGLPDTILNKMQSRNGSDPFTFKS 710
            |....:::.|..:.:|                  .|:..|||
Zfish   655 AAGSAYMINDAATILP------------------RAVVAKAR----------------------- 678

  Fly   711 IKALLAMLQAPIINSKDLHLEFILQMEGKTVLSYYLNQRMFRQLTYDNILERMQQIIRTDSHINM 775
              ..||...|.::       ||.::..|       :|:.:.:....|..::|:.:|.||...:.
Zfish   679 --TYLAGAAADVV-------EFGVRTGG-------INEALLKSPAADESVDRITKIKRTLKALT- 726

  Fly   776 QTVRWPFMNRYTVPTVLGTSSDVLLQTTVLTSLRGNITEQRNSPITKHTLEIDARYSSYASVRSR 840
                    |...:||                          :.|:.          |:|..|..:
Zfish   727 --------NWKALPT--------------------------DKPLA----------SAYVKVFGQ 747

  Fly   841 SYNPFLNLDHEINREQGFLIYIPFSSELHLNESGSKCRRYSFSRPQNLTSGLSF---KSRAVTKT 902
            .. .::|.|..|..|.     ||.       .:|.|.|.......:.|..|::|   |.....:.
Zfish   748 EV-AYVNFDKTIIEEA-----IPM-------VTGPKPRALLKEALKALQEGVAFQYAKPLLAAEV 799

  Fly   903 RGLITKTAAAPFEEIMVPEGRNDVVQLFSY-----PMTDLGVRLSMTTNLNELIKYRGMLLKS-E 961
            |.::......|.|              ||:     ....:.|:.::|..|.|  |...|..:. :
Zfish   800 RRILPTAVGVPME--------------FSWYTAAVAAASVNVQATITPALPE--KLESMTYEQLK 848

  Fly   962 FTENGFSGNMVVNALMYIF-------GFTQLSSIHLGHDRNFTMLMYNEKNTRIEGNFCAEDVLK 1019
            .|:..|......:..:..|       .|.|.:.:..|..|.........:...::||:..|
Zfish   849 KTDVQFQAEARPSVALQTFAVMGVNTAFIQAAVMARGKIRTIAPGKVAARADILKGNYKVE---- 909

  Fly  1020 TSDMKGKQIGLTLEHTDHMN----ENHAADALHRWNITLDVLASTKSNWFKLTGQ--VQRNSKDD 1078
                     .|.::..:|:.    |.||        :..::...:......|..|  :|.:...:
Zfish   910 ---------ALPVDLPEHIASASFETHA--------VVRNIEDHSAERSVPLVPQLSLQNSQTSN 957

  Fly  1079 EDDWKA------------------CTKLTYEPLVFTKRPHTLNGDVV---------------FGL 1110
            .:||.:                  |..:.|..:......|:.|...:               ..:
Zfish   958 ANDWSSEMSPDVSVKAPAPFDRTLCYAVPYIEIKGCVEVHSHNAAFIRNSTLFYIIGQHSAHVAV 1022

  Fly  1111 ATEESECPEKGSTVQFAARAGPSEHARAFLRSDK-ISLTDTDFCP---------KEVL----KFS 1161
            |..|....|:   ::|..:.||    ||..|..| |::.|.| .|         :|:|    |.:
Zfish  1023 ARAEGPAVER---LEFEVQVGP----RAAERLVKQINIIDDD-TPEGQAFLLKLREILDTEAKNA 1079

  Fly  1162 PIPTSRYCKRSNFENFTSITQYDMDLKFDNMPAWFELWSNRLDHLVSALSADKVDSLHMSQEINI 1226
            |:.:.   ..|:..|..||:....:..           ||......|:.|:....|..||.....
Zfish  1080 PVSSE---SSSSSRNSRSISSSSSNSN-----------SNSSSSSSSSSSSSSSSSSSMSSSRMS 1130

  Fly  1227 SMQTPQDQFRLAVEVNGVKWRFHQIPFFYKLDSKFDASHELT-----------FDSGLKRSCSVI 1280
            ...|..:.||          :||:        .::.|:|..|           |:...|::..:.
Zfish  1131 KTATIMEPFR----------KFHK--------DRYLAAHSATKDTSSGSAAASFEQMQKKNRFLG 1177

  Fly  1281 NGIVNTFDDYLINLREIAVRPDCLTLLVADCSPLPQIAVFVTPSP-VQGLSTNYGLRVHIGQNYF 1344
            |.|...|   .|..|.:......|...:|        |.|..|:. ||.::::.
Zfish  1178 NDIPPVF---AIIARAVRADQKLLGYQLA--------AYFDKPTARVQLIASSI----------- 1220

  Fly  1345 NFRARTDNSSLPTDEPVLIYLNQDQTPHNVRKKPYQWPIETSDY 1388
               |..||..:..|..:|       :.|.|..| :.|..|...|
Zfish  1221 ---AENDNMKICADGALL-------SKHKVTAK-FSWGAECKQY 1253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-d	NP_732076.1	LPD_N	28..589	CDD:214755	130/632 (21%)
		DUF1943	632..>813	CDD:286281	26/180 (14%)
		VWD	1277..1435	CDD:295339	23/113 (20%)
vtg6	NP_001116082.3	Vitellogenin_N	35..603	CDD:279663	130/641 (20%)
		DUF1943	637..928	CDD:286281	67/434 (15%)
		DUF1944	1182..1346	CDD:286284	21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581665
Domainoid	1	1.000	54	1.000	Domainoid score	I11190
eggNOG	1	0.900	-	-		E1_KOG4338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25081at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26552
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850