Protein Alignment cv-d and LOC100494633

DIOPT Version :9

• Sequence 1: NP_732076.1
• Gene: cv-d / 41921
• FlyBaseID: FBgn0265048
• Length: 1470
• Species: Drosophila melanogaster
• Sequence 2: XP_004913968.3
• Gene: LOC100494633 / 100494633
• -ID: -
• Length: 1812
• Species: Xenopus tropicalis
• Alignment Length: 1868
• Identity: 328/1868 - (17%)
• Similarity: 601/1868 - (32%)
• Gaps: 673/1868 - (36%)

  Fly    28 NKQMLYEYEGNVLVGAKPQDEGHQAPPTTGWIVRGKLTLQRQSELVLAAALVIDDVTLNNSG--- 89
            :|..:|.|||.:|.|.          |..| :.|..:.|..:.|:               ||
 Frog    32 SKTYVYNYEGLILNGI----------PQNG-LARSGIKLNCKVEI---------------SGYAQ 70

  Fly    90 EKFL---QNKEMYP-----PYKPFKIA----------LT-------KDGAISHVVFKEGDPIWSM 129
            ..:|   :|.|:..     |..||..|          ||       |:|.:..:...|.....::
 Frog    71 RSYLLKIRNPEIKEFNGLWPKDPFTRATKLSQILAEQLTRPAKFEYKNGQVGKIFAAEDVSETAL 135

  Fly   130 NFKRAIASVLQFQMKSS-GAFVVDELGIHGTCRTEYFV--SNRTNYISIRKTPEVKTCK------ 185
            |.::.|.::||..:|:| ..:.:.|..|.|.|.|:|.|  ..:.:.:::.|:.:...|:
 Frog   136 NIQKGILNLLQVTLKASQDVYDLQEECISGVCHTKYTVQQDKKADRLTVIKSRDFDNCQSRVEKK 200

  Fly   186 ---PYSEAVH--TTRSNVPPNTCEFDH------QKSVIIGNEA--IYGMSPH--------NETGY 229
               .|.|...  ..|:.....:..|.:      |.::|:...|  :|..:|:        .|...
 Frog   201 IGVAYMETCSQCQKRAQNLRGSATFTYKLQNKDQGALIVEASAKQVYRYTPYYELYGAAVMEARQ 265

  Fly   230 YLSMAHAKGTTLIHTFESTGEAQFIN-SELLLNFLNETPIDNPIDIETSMAAEPSNLE-LQRLDP 292
            .|::|..|...:     |..:.|..| ..|..:|..|.. ..|..:..:..||...:| ||.|..
 Frog   266 ILTLAETKSNRI-----SESQIQLTNRGGLNYHFWQEEH-QMPFQLLKTKNAESQVVETLQHLVQ 324

  Fly   293 NDPTGGRSPQQQETLIAQAGTLLDSLAEALETTEFKFSEPYDSTLSDVIKLLSEMDFDSLTKLYR 357
            |:                     ..|.....|::|          ..:::||...:.:::..:::
 Frog   325 NN---------------------QDLVHGESTSKF----------LQLVQLLRATNQENIQAIWK 358

  Fly   358 EVDIGTSYRQETIRNIFHEIIPRIGTKASVFLTHHLVLNK-LTKPQIAVQLLIPMPF-----HIF 416
            :......:|...:     ..||..|:..::.....::.|: ||..:.|..:|:.|.:     .:.
 Frog   359 QFSDRPQHRHWLL-----NAIPMSGSVDALKFIKQMIHNQDLTHQEAATAILMAMHYTKATQRVM 418

  Fly   417 ELSAELV--QKCEDFLNIGPDRPDVRQAAILSFATLIHNVYVAKGIDKEKFEEYVQKYFN---AY 476
            |::|:||  .|.::|       |.:.::|:|::.:|::...|    |.:...|...:..:   |.
 Frog   419 EIAADLVTDSKVQNF-------PTLYKSAMLAYGSLVYKYCV----DSQSCPEAALQPLHELAAE 472

  Fly   477 LSDRDFDQKM-LYLQGLNN----LQLGNVANYLEPIVQDPNEHEDLKFQA----AWTTLALADRR 532
            .:.:...::: |.|:.:.|    ..:..:..::: :.........::.|.    |...:|:.|.|
 Frog   473 AASKGHQEEITLALKAIGNAGQPASIKRLQKFMQ-VFSSGASRLPVRVQTDAVMALRNIAIKDPR 536

  Fly   533 AERIYEVYWPIFESRNASLELRVAAVTLLLISNPTAARLISIHRII--QSETDPHMINYYRTTVT 595
              ::.||...||..|:...|:|:.....|..:||..|.:.::...:  :|:.:..:.::..:.:.
 Frog   537 --KVQEVLLQIFMDRDVHPEVRMITCVALFETNPGVAIVTAVANAVLRESKDNLQLASFTYSHIK 599

  Fly   596 SISETTYPCYQHL----RRLLSYMHRHLPQKPESRYWVTGNYIFD---YRDSK-FGI-------- 644
            |:|::|.|.:.:|    |..|:.:                |.:||   :|.|| |.:
 Frog   600 SLSKSTMPEFHNLASACRVALNIL----------------NPVFDQLSFRYSKAFHVDTYNYPMM 648

  Fly   645 -GAMLQVFLVGDPKSDMPVVAFFKFDTEALGKFTGQLALYIKARGLPDTILNKMQSRNGSDPFTF 708
             |..|.||.:..|::.:|:.|..|......|..:..|...::|.||.: ::.|...:........
 Frog   649 GGLALNVFFINSPRTAIPMFALVKVRGSFAGASSDILEFAVRAEGLQE-VIRKQNIQFSEYSMRK 712

  Fly   709 KSIKALLAML-------QAPIINSKDLHLEFILQMEGKTVLSYYLNQRMFRQLTYDNILERMQQI 766
            |.:|.|.|||       ..|::::.       :::.|:.|        .|.|.|.|.|...::.:
 Frog   713 KIVKILKAMLAYKEAPANVPLVSAS-------IKILGQEV--------TFNQATRDTIQNAVKLL 762

  Fly   767 IR-TDSH----------INMQTVRW--PFM---NRYTVPTVLGTSSDVLLQTTVLTS-------- 807
            .. .|.|          ::..|.:|  |.:   .||.:||.:|...::...|..:.:
 Frog   763 NEPADRHTVVKKVLNRLLSGATGQWSHPMLVAEARYIIPTCVGFPLEIATHTAAVANAAINADMK 827

  Fly   808 --------------LRGNI----------------TEQRNSPITKHTLE---------------- 826
                          |..||                |...|:|:.:..||
 Frog   828 VTPSPSNDFSLSQLLESNIQLHTDMSPSVLIHTVDTMGVNTPVIQSGLEYHGKFRLQAPAKLTAK 892

  Fly   827 ---------------------IDARYSSYASVRSRSYNPFLNLDHE-----INREQGFLIYIPFS 865
                                 :.||:..:|..|:..     .||.|     :.::.|     |.:
 Frog   893 LDMHGKNFKIETPPCQREVELLTARHQMFAVTRNVG-----QLDSEKRMQVVPKQHG-----PST 947

  Fly   866 SELHLNESGSKCRRYSFSRPQNLTSGLSFKSRAVTKTRGLITKTA----AAPFEEIMVPEGRNDV 926
            .|.|..:||.             ||..|.....|:...|| .|.|    .|.::.|  |..
 Frog   948 LEQHFEKSGR-------------TSAESASMMEVSSEMGL-RKNAYSVGGAEYQRI--PNN---- 992

  Fly   927 VQLFSYPM--TDLGVRLSMTTNLNE--------LIKYRG-----MLLKSEFTEN----------- 965
            |:.|.|.:  :.|.:...:.:.||.        |..|.|     :.:|.  |:|
 Frog   993 VESFHYCLRFSKLNINACLQSKLNTAQGDRRSFLYDYIGEHETKIFIKP--TQNDAAIEKLQLEI 1055

  Fly   966 ----GFSGNMVVNALMYIFGFTQLS--------SIHLGHDRNFTMLMYNEKNTRIEGNFCAEDVL 1018
                |.|..::..|.:......||.        .|.||.:.:    .|:.:|..:.|.  ...|.
 Frog  1056 TAGPGASSKLMALAEVEKTEGEQLDESAVQKRLKIILGINED----EYSARNKSLVGK--KRKVK 1114

  Fly  1019 KTSDM----------------------------------------------------------KG 1025
            ||.|.                                                          :|
 Frog  1115 KTKDAAETEVVEAKQNWKQSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPQRNSRHRG 1179

  Fly  1026 KQIGLTL------------------EHTD------------------------------------ 1036
            .::.|..                  :|.|
 Frog  1180 SKVDLLSRVSQQAKNKDTHAQTGRNKHRDSSSSESSSSGSSSSESSSSSSSSSSSSSSSESSSSS 1244

  Fly  1037 -HMNENHAADALHRWNITLDVLASTKSNWFKLTGQVQRNSKDDE-------DDWKACTKLTYEPL 1093
             ..|..|.....|:        .|:|.       |..||.::.:       :|........|: |
 Frog  1245 SESNRRHGKSGKHQ--------QSSKQ-------QTHRNKQNQQKHHGRHYEDMSQMPPELYK-L 1293

  Fly  1094 VFTKRPHTLNGDVVFGLATEESECPEKGSTVQFAARAGPSEHARAFL---------------RSD 1143
            .| :||:.   ....|::::.||.....|: ..::.:..|.|...||               |:|
 Frog  1294 RF-QRPYK---QQYKGMSSQSSESSSSSSS-SSSSESARSPHHNKFLGDKKPPTVVITAQAVRND 1353

  Fly  1144 K-------ISLTDTDFCPK---EVLKFSPIPTSRYCK----RSNFENFTSI------TQYDMDLK 1188
            .       |..||....||   .|:..:.....|.|.    |:.:|....:      .||.|::.
 Frog  1354 NAKQGYQVILYTDYTSRPKMQAYVVDITGKSRWRACAAAYVRNPYEAQAELKWGQNCKQYKMEVV 1418

  Fly  1189 -----FDNMPA------WFELWSNRLDHLVSALS---ADKVDSLHMSQEINISMQ-TPQDQFRLA 1238
                 |.|.||      |     .|:...:.:|.   |:.:.........|...| .|..|.::.
 Frog  1419 AQTGIFGNQPALRLKVNW-----PRIPSKLKSLGQQVAEFLPGTAYMMGFNTKFQRNPSKQAKIV 1478

  Fly  1239 VEVNG---------VKWR--FHQ---IPF----FYKLDSK---------FDASHELTFDSGLKRS 1276
            ..::.         |.|.  ::|   |||    .|.|.|.         |..::....|. |...
 Frog  1479 FSLSSPRTMNAVIQVPWATCYYQAINIPFAVTAAYHLHSADIQAPTWSIFADTYSSLVDR-LSGE 1542

  Fly  1277 CSVINGIVNTFDDYLINLREIAVRPDCLTLLVADCSPLPQIAVFVTPSPVQGLSTNYGLRVHIGQ 1341
            |::.|..:.||::...|   ..:...|..:|..||||..:..|....||  |.|....:.:.:
 Frog  1543 CTMSNDQIKTFNEVKFN---YTLPGSCFHVLAQDCSPELKFLVMAKKSP--GSSEMRDINIKL-- 1600

  Fly  1342 NYFNFRARTDNSSLPTDEPVLIYLNQDQTPHNVRKKPYQWPIETSDYDFRVELNEQNILIVECTQ 1406
                  |..|.....:.|.:.:.:|..:.|  :.|.||   |.:.|....:::.|...
 Frog  1601 ------ADYDIDMYTSSEEIRLKVNGLEVP--MEKLPY---IASKDPAVEIKMEEGAF------- 1647

  Fly  1407 LSSTIQFDLYNILNFEIYGV-----------------YKHQMCGLCSK 1437
                       ||:..::||                 .:...||:|.:
 Frog  1648 -----------ILSAPVFGVEQLYYNGKSTKVRTAVWMRGSTCGICGR 1684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-d	NP_732076.1	LPD_N	28..589	CDD:214755	117/642 (18%)
		DUF1943	632..>813	CDD:286281	49/254 (19%)
		VWD	1277..1435	CDD:295339	33/174 (19%)
LOC100494633	XP_004913968.3	Vitellogenin_N	29..599	CDD:396081	117/648 (18%)
		DUF1943	633..916	CDD:401204	51/298 (17%)
		DUF1944	1341..1506	CDD:401207	30/169 (18%)
		VWD	1540..1698	CDD:214566	34/181 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25081at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010