Protein Alignment spn-E and hrpB

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_414690.4
• Gene: hrpB / 944845
• ECOCYCID: EG12329
• Length: 809
• Species: Escherichia coli
• Alignment Length: 540
• Identity: 138/540 - (25%)
• Similarity: 233/540 - (43%)
• Gaps: 105/540 - (19%)

  Fly   114 NLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISI 178
            :|.:.|...|:|.|::..|.|::...||.||:|.:|..:|.....:||   |::.:|||:||.::
E. coli     3 SLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAHPGINGK---IILLEPRRLAARNV 64

  Fly   179 ANRVCQEREWQQNTVCSFQVGLHR---PNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEV 240
            |.|:.:....:......:::....   ||    |||...|.|||...:..:..|:....::|||.
E. coli    65 AQRLAELLNEKPGDTVGYRMRAQNCVGPN----TRLEVVTEGVLTRMIQRDPELSGVGLVILDEF 125

  Fly   241 HERDQNMDF---LLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHS 302
            |||....|.   ||:.|::.|..:   :|:::||||:|...|.....   ..|.||:..  |...
E. coli   126 HERSLQADLALALLLDVQQGLRDD---LKLLIMSATLDNDRLQQMLP---EAPVVISEG--RSFP 182

  Fly   303 IEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEAL---- 363
            :|:.|                  :|                         :.:.|.:|:|:
E. coli   183 VERRY------------------LP-------------------------LPAHQRFDDAVAVAT 204

  Fly   364 ------RYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSLMTPENQRDVFNPPPPGF 422
                  ..|::|:||||:.||..:.|.|...:.:|    |.:...:..::..:||....|.|.|.
E. coli   205 AEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGSD----VLLCPLYGALSLNDQRKAILPAPQGM 265

  Fly   423 RKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSG 487
            ||::|.|||||:|:|:..:..|:|....:|...|..:..:.|.....|:|:..|||||.|||..|
E. coli   266 RKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPG 330

  Fly   488 RVYRMVNKHFYQREMPEFGI----PEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHN 548
                 ::.|...:|..|...    ||:|:..|...:::........|.::  ..|..|.:.::..
E. coli   331 -----ISLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQM--SWLDQPPVVNLLA 388

  Fly   549 TILLLKEVGALYLTVDGIYDPLDGD-LTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAG 612
            ...||:.:||           |:|: |:..|..|:.|..|.|.:.:::.....:....|..|||.
E. coli   389 AKRLLQMLGA-----------LEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAI 442

  Fly   613 LSTPGLFAHEGGRSQLGDSF 632
            |..|...    |.|.||.:|
E. coli   443 LEEPPRM----GNSDLGVAF 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	138/540 (26%)
		DEXHc_TDRD9	115..295	CDD:350746	55/185 (30%)
		TUDOR	892..1016	CDD:425754
hrpB	NP_414690.4	PRK11664	1..809	CDD:236950	138/540 (26%)