Protein Alignment spn-E and PRP16

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_013012.3
• Gene: PRP16 / 853961
• SGDID: S000001794
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 660
• Identity: 185/660 - (28%)
• Similarity: 298/660 - (45%)
• Gaps: 99/660 - (15%)

  Fly    54 SKIVAKEKCLL--------NGTLLNEQPQGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLN 110
            ||:||..:..:        |.|:|| ...|: :..|::.:...:....:|..|...:...:.::.
Yeast   282 SKLVALRRINMEHIQQSRDNTTVLN-TAMGE-VLGLENNNKAKDKSNQKICDDTALFTPSKDDIK 344

  Fly   111 RDK-NLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIA 174
            ..| .|.::..|.::|:.|..:.||:|.||||.|||||:.||:.:|.|.:.:..:||||||||:|
Yeast   345 HTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKSIVVTQPRRVA 409

  Fly   175 AISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDE 239
            |||:|.||..|.:........:.:........|.|:|.:.|.|:||...:.:.||..|:.:::||
Yeast   410 AISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTLDKYSCVIIDE 474

  Fly   240 VHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTN--SIPPVITTNHRRKHS 302
            .|||..|.|.||...:.||| ..|.:|:|:.|||::||:.|.:|....  :||       .|...
Yeast   475 AHERSLNTDILLGFFKILLA-RRRDLKLIITSATMNAKKFSAFFGNAPQFTIP-------GRTFP 531

  Fly   303 IEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGA 367
            ::..|..              ..|.:..:.....||||.:..|                 ...|.
Yeast   532 VQTIYTS--------------NPVQDYVEAAVSQAVKIHLAND-----------------CSSGD 565

  Fly   368 VLIFLPGIYEIDTMAENL-------------TCMLE--NDPNIKVSIVRCFSLMTPENQRDVFNP 417
            :|||:.|..:|:|..:.|             |...|  ||    :.|:..:|.:..:.|..:|..
Yeast   566 ILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEIND----IEILPIYSALPADLQFKIFQD 626

  Fly   418 PPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVG 482
            .....||||:.|||||:|:|:..:.||||...:|:||.:......||.:|..||||..||:||.|
Yeast   627 LHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISKANADQRSGRAG 691

  Fly   483 RLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIH 547
            |...|..||:..:..::.:|....|||:.|..|.|::|..|.|::...:........|| |....
Yeast   692 RTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDELSKFPFIDKPP-LQTFL 755

  Fly   548 NTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAG 612
            :::..|..:||:         ...|.||..|..|::.||....|:::::.......:|.:.|.:.
Yeast   756 SSLYELWFIGAI---------DTSGQLTPLGLQMAKFPLQPSLSKILLIAVRNGCSDEMLTIVSM 811

  Fly   613 LSTPGLFAHEGGRSQLGD----SFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWA 673
            ||.|.:|.....|.:..|    .|::       :.||       :||.||:.|.......:..|.
Yeast   812 LSVPQVFYRPKERQKEADIARNKFFI-------AKSD-------HLTLLNVFEQWRANNFSSHWC 862

  Fly   674 KRFHVSLRSL 683
            .:..|..:||
Yeast   863 NKHFVQYKSL 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	172/591 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	70/181 (39%)
		TUDOR	892..1016	CDD:425754
PRP16	NP_013012.3	HrpA	348..>980	CDD:441249	172/592 (29%)