DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spn-E and AT1G58060

DIOPT Version :9

Sequence 1:	NP_476741.1	Gene:	spn-E / 41919	FlyBaseID:	FBgn0003483	Length:	1434	Species:	Drosophila melanogaster
Sequence 2:	NP_176103.2	Gene:	AT1G58060 / 842173	AraportID:	AT1G58060	Length:	1459	Species:	Arabidopsis thaliana

Alignment Length:	968	Identity:	277/968 - (28%)
Similarity:	426/968 - (44%)	Gaps:	186/968 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LMATKFKSSEVPNRELIGTDYVSKIVAKEKCLL---NGTLLNEQP-QGKRIRTLDDL-------- 84
            |:.|..:|:|...|    .::|.|::.::...|   :.:..|..| ....::..|||
plant   517 LLCTTIQSTEEDRR----ANFVDKLLEEDSFSLTTSSSSFENSLPLVDSYVKDKDDLGVVKSNNR 577

  Fly    85 ---DTDDEGEETEIRRDDEYYK---KFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCG 143
               |:..|.|...::|..|..|   |::..|.....|.|...:..||..:....|:::.||||.|
plant   578 AKRDSYIEAECLSLQRKQENKKRTQKYKDMLKTRTALPISEVKNGILQHLKEKDVLVVCGETGSG 642

  Fly   144 KTTQVPQYILDEAYKSGK--YCNIVVTQPRRIAAISIANRV----CQEREWQQNTVCSFQVGLHR 202
            |||||||:|||:...||.  ||||:.||||||||||:|.||    |:......:::..:||.|..
plant   643 KTTQVPQFILDDMIDSGHGGYCNIICTQPRRIAAISVAQRVADERCESSPGLDDSLVGYQVRLES 707

  Fly   203 PNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLA-----TNS 262
            ..| :.||||:||||:||..|..::||...|||::||||||....|||||:::.|:.     ..|
plant   708 ARS-DKTRLLFCTTGILLRKLAGDRTLNDVTHIIVDEVHERSLLGDFLLIILKSLIEKQSCDNTS 771

  Fly   263 RHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHR----RKHSIEKFY---------------- 307
            |.:|:||||||:||...|.||...    ||||...|    ..|.:|:.|
plant   772 RKLKVILMSATVDADLFSRYFGHC----PVITAQGRTHPVTTHFLEEIYESINYLLAPDSPAALR 832

  Fly   308 -----RDQLGSII------------WNE-----EDVGHQQVPEINKHGYRAAVKIIVIIDNMERK 350
                 :|:|||:.            |.:     ||..:......|.:.|....:     .|::|
plant   833 SDTSIKDKLGSVNDRRGKKNLVLAGWGDDYLLSEDCLNPFYVSSNYNSYSDQTQ-----QNLKR- 891

  Fly   351 AAIQSRQSY----------DEALRYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSL 405
             ..:.|..|          |:....||:||||||:.||..:.:.|.............::...|.
plant   892 -LNEDRIDYELLEELICHIDDTCEEGAILIFLPGVAEIYMLLDMLAASYRFRGPAADWLLPLHSS 955

  Fly   406 MTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWAS 470
            :....||.||..||.|.||:|..|||||:|||:.||.||||....|....:.....||:...|.|
plant   956 IASSEQRKVFLRPPKGLRKVIAATNIAETSITIDDVVYVIDSGKHKENRYNPQKKLSSMVEDWIS 1020

  Fly   471 KANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILA 535
            :||.|||.||.||::.|..:.:..::.:::.|..:.:|||||:||....|:.|:|.:|.....|:
plant  1021 QANARQRTGRAGRVKPGICFSLYTRYRFEKLMRPYQVPEMLRMPLVELCLQIKLLGLGHIKPFLS 1085

  Fly   536 LALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIF 600
            .||.||:...:.:.|.||.||||    |:|     |.:||..|..:::||:|....::::.|.||
plant  1086 RALEPPSEGAMTSAISLLHEVGA----VEG-----DEELTPLGHHLAKLPVDVLIGKMLLYGGIF 1141

  Fly   601 NMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDG-SGSDL---------VAIWRVYLT 655
            ..|...:.|||.||....|.:.....|..|...:..:..:| |.|||         :.:...|..
plant  1142 GCLSPILSIAAFLSYKSPFIYPKDEKQNVDRVKLALLSDNGVSSSDLNNNDRQSDHLLMMVAYDK 1206

  Fly   656 YLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLVQELRVR----CTHLGLIPF----------- 705
            ::.|:     ||..::.|:||..|......:..:::::||:    ...:|||..
plant  1207 WVKIL-----QERGMKAAQRFCESKFLSSSVMRMIRDMRVQFGTLLADIGLINLPKTGEFSGRKK 1266

  Fly   706 ---------PVNPNQMMDDREKAIMLKVIIAGAFYPNYFTRSKESCADTDRNIYQTISGHDPCRT 761
                     |..|..|...:.:.:  |.|:....|||        .|..|:.|.:|.......:.
plant  1267 ENLDVWFSDPTQPFNMYSQQPEVV--KAILCAGLYPN--------IAANDKGITETTFNSLTKQG 1321

  Fly   762 VYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVTFQEGSQKVFVTFKQDDWIEGSSKYVPVSG 826
            ....::...|.|.          :||.|.|.:::..| :..|..|:.|.:
plant  1322 NQTKSYSAWYDGR----------REVHIHPSSINSNF-KAFQNPFLVFLE--------------- 1360

  Fly   827 RVQSEVYKAVMMRQNRVERPIHIMNPSAFMSYVQQRGIGDVIEGRWIPPTKPLNVELL 884
            :|::   ..|.:|...:..|..|:.....::...|.| ...|:| |:....|....:|
plant  1361 KVET---NKVYLRDTTIVSPFSILLFGGSINVHHQSG-SVTIDG-WLKVAAPAQTAVL 1413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	219/660 (33%)
spn-E	NP_476741.1	TUDOR	892..1016	CDD:395449
AT1G58060	NP_176103.2	DSRM	411..492	CDD:214634
		HrpA	574..1371	CDD:224557	254/861 (30%)
		DEXDc	632..782	CDD:238005	75/150 (50%)
		Helicase_C	904..1035	CDD:278689	51/130 (39%)
		HA2	1105..1182	CDD:214852	25/85 (29%)
		OB_NTP_bind	1242..1387	CDD:285018	30/183 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820