DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-E and AT2G35920

DIOPT Version :9

Sequence 1:	NP_476741.1	Gene:	spn-E / 41919	FlyBaseID:	FBgn0003483	Length:	1434	Species:	Drosophila melanogaster
Sequence 2:	NP_001323636.1	Gene:	AT2G35920 / 818165	AraportID:	AT2G35920	Length:	1027	Species:	Arabidopsis thaliana

Alignment Length:	845	Identity:	254/845 - (30%)
Similarity:	391/845 - (46%)	Gaps:	169/845 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 DTDDEGEETEIRRDDEYYK--------KFRFNLN------------------RDKNLSIYAKREE 123
            |..|......::|.|...|        ||.|.|.                  |:| |..:..:||
plant   205 DQQDRTSTLGLKRPDSASKLPDSLEKEKFSFALKERQEKLKATESVKALKAFREK-LPAFKMKEE 268

  Fly   124 ILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS--GKYCNIVVTQPRRIAAISIANRVCQER 186
            .|.:::.:.|:::.||||||||||:||:||:|...|  |..|||:.||||||:|||:|:|:..||
plant   269 FLNSVSQNQVLVVSGETGCGKTTQLPQFILEEEISSLRGADCNIICTQPRRISAISVASRISAER 333

  Fly   187 EWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLL 251
            .........:|:.|....| :.||||:|||||||..||.:..||:.:|:::||:|||..|.||||
plant   334 GESIGESVGYQIRLESKRS-DQTRLLFCTTGVLLRRLIEDPNLTNVSHLLVDEIHERGMNEDFLL 397

  Fly   252 IVVRRLLATNSRHVKIILMSATIDAKELSDYF--TTTNSIP----PVI----------------- 293
            |::|.||.... .:::|||||||:|...|.||  :.|..||    ||.
plant   398 IILRDLLPRRP-DLRLILMSATINADMFSTYFGNSPTMHIPGFTFPVAELFLEDVLEKSRYNIKS 461

  Fly   294 --------TTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKH--GYRAAVKIIVIIDNME 348
                    ::..||:.|..|  :|.|.::.   ||:      :||.|  .|.:|.:     :::|
plant   462 SDSGNYQGSSRGRRRESESK--KDDLTTLF---EDI------DINSHYKSYSSATR-----NSLE 510

  Fly   349 RKAAIQSRQSYDEA-LRY-------GAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSL 405
            ..:..|......|| :.:       ||:|:||.|..||..:.|.:........:.|..::.....
plant   511 AWSGAQIDVDLVEATIEHICRLEGGGAILVFLTGWDEISKLLEKINMNNFLGDSSKFLVLPLHGS 575

  Fly   406 MTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWAS 470
            |...|||::|:.|||..|||:|.|||||||||:.||.||:|...||....|..:..:.|..:|.|
plant   576 MPTVNQREIFDRPPPNKRKIVLATNIAESSITIDDVVYVVDCGKAKETSYDALNKVACLLPSWIS 640

  Fly   471 KANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILA 535
            ||:..||.||.||:::|..||:..|..|. ..|::.:||::|.|||...|..|.|.:||....||
plant   641 KASAHQRRGRAGRVQAGVCYRLYPKVIYD-AFPQYQLPEIIRTPLQELCLHIKSLQVGSIGSFLA 704

  Fly   536 LALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIF 600
            .||.||:...:.|.|.|||.:|||        :.:: :||..|..:..||:|....:::::|.||
plant   705 KALQPPDALAVENAIELLKTIGAL--------NDVE-ELTPLGRHLCTLPVDPNIGKMLLIGAIF 760

  Fly   601 NMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHD 665
            ..:..|:.|||.|:....|.....|.:..|....:  |:..|.||.:|:.:.|..|.:....|::
plant   761 QCVNPALTIAAALAYRSPFVLPLNRKEEADEAKRY--FAGDSCSDHIALLKAYEGYRDAKRGGNE 823

  Fly   666 QESAIRWAKRFH-VSLRSLKEIHLLVQELRVRCTHLGLI--PFPVNPNQMMDDREKAIMLKVIIA 727
            ::..  |..... |:||.::::.....:|   .:.:|.:  ..|...||...|.|   |:..::.
plant   824 KDFC--WQNFLSPVTLRMMEDMRNQFLDL---LSDIGFVDKSKPNAYNQYSYDME---MISAVLC 880

  Fly   728 GAFYPN------------YFTRS-------------------------KESCADTDRNIYQTISG 755
            ...|||            ::|:.                         .|....|...|..:.:.
plant   881 AGLYPNVVQCKRRGKRTAFYTKELGKVDIHPGSVNARVNLFSLPYLVYSEKVKTTSVYIRDSTNI 945

  Fly   756 HDPCRTVYFTNFKPAYMGE--------LY---TRRIKELFQEVR----------IPPENMDVTFQ 799
            .|....::..|..|:..||        |:   ::.|.||.|.:|          |...::|:|.:
plant   946 SDYALLMFGGNLIPSKTGEGIEMLGGYLHFSASKNILELIQRLRGEVDKLLNKKIEDPSLDITVE 1010

Fly 800 799
plant 1011 1010

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	216/627 (34%)
spn-E	NP_476741.1	TUDOR	892..1016	CDD:395449
AT2G35920	NP_001323636.1	HrpA	225..941	CDD:224557	235/754 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820