DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spn-E and HVT1

DIOPT Version :9

Sequence 1:	NP_476741.1	Gene:	spn-E / 41919	FlyBaseID:	FBgn0003483	Length:	1434	Species:	Drosophila melanogaster
Sequence 2:	NP_850154.2	Gene:	HVT1 / 817631	AraportID:	AT2G30800	Length:	1299	Species:	Arabidopsis thaliana

Alignment Length:	819	Identity:	225/819 - (27%)
Similarity:	361/819 - (44%)	Gaps:	167/819 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLNRDK----------NLSIYAKREEILAAI 128
            :||:.:..||.....:....||.   |........|.:||          .|.|.:.::.|.:|:
plant   139 KGKQGQWKDDFFRKPQISSEEIL---EKVASLSSRLKKDKALKEITKLRSKLPITSFKDAITSAV 200

  Fly   129 NAHPVVIIKGETGCGKTTQVPQYILDEAYKSGK-YCNIVVTQPRRIAAISIANRVCQEREWQQNT 192
            .::.|::|.||||||||||||||:||..:.|.: .|.||.||||||:|:|::.|:..||......
plant   201 ESNQVILISGETGCGKTTQVPQYLLDHMWSSKRETCKIVCTQPRRISAMSVSERISCERGESIGE 265

  Fly   193 VCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINN---KTLTHYTHIVLDEVHERDQNMDFLLIVV 254
            ...::|.|..... ..:.:::||.|:||..|:..   .:::..|||::||:||||...||:|.::
plant   266 NIGYKVRLQSKGG-RHSSVVFCTNGILLRVLVGKGSVSSVSDITHIIVDEIHERDCYSDFMLAII 329

  Fly   255 RRLLATNSRHVKIILMSATIDAKELSDYF--TTTNSIP----PVIT--------------TNHRR 299
            |.||.:|. |:::||||||:||:..|.||  .....:|    ||.|              .||..
plant   330 RDLLPSNP-HLRLILMSATLDAERFSGYFGGCPVVRVPGFTYPVRTLYLEDVLSILKSGGDNHLS 393

  Fly   300 KHSI------------EKFYRDQLGSIIWNEED-------------------------------- 320
            ..::            :|...|:...:.|..::
plant   394 STNLSISDHKLDLTDEDKLALDEAIILAWTNDEFDALLDLVSSRGSHEIYNYQHQSTWLTPLMVF 458

  Fly   321 VGHQQVPEI-------------NKHGYRA-----------AVKII-VIIDNMERKAAIQSRQSYD 360
            .|..::.::             :|.|..|           |.:|| ...||.:..:. |.:|..|
plant   459 AGKGRISDVCMLLSFGADWSLKSKDGMTALELAEAENQLEAAQIIREHADNSQSNSQ-QGQQLLD 522

  Fly   361 EAL------------------------RYGAVLIFLPGIYEIDTMAENLTCMLEND---PNIKVS 398
            :.:                        ..||:|:||||..:|:...:.|   |||.   .:.|..
plant   523 KYMATINPEQVDVSLIQQLMRKICGDSEDGAILVFLPGWDDINKTRQRL---LENPFFADSAKFD 584

  Fly   399 IVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSS 463
            |:...|::....|:.|||.||||.|||:|.||||||::|:.||.||||....|.|..|..::.|:
plant   585 IICLHSMVPAGEQKKVFNRPPPGCRKIVLATNIAESAVTIDDVVYVIDSGRMKEKSYDPYNNVST 649

  Fly   464 LRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQR----EMPEFGIPEMLRLPLQNSVLKAKV 524
            |:.:|.||||.:||.||.||.:.|..|     |.|.|    .||:|.:||:.|:|::...|:.|:
plant   650 LQSSWVSKANAKQRQGRAGRCQPGICY-----HLYSRLRAASMPDFKVPEIKRMPVEELCLQVKI 709

  Fly   525 LNMGSPV-EILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDT 588
            |:..... :.|...|.||....|.|.:.:|:::|||        .|.: :||..|.....||:..
plant   710 LDPNCKTNDFLQKLLDPPVDQSIANALSILQDIGAL--------TPQE-ELTELGEKFGHLPVHP 765

  Fly   589 RQSRLIILGYIFNMLEEAIII--AAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWR 651
            ..|:::....:.|.|:.|:.:  ||....|..........|...:..:......|..||.:|:..
plant   766 LISKMLFFAVLVNCLDPALTLACAADYKEPFTMPMSPVERQKAAAAKLELASLCGGDSDHLAVVA 830

  Fly   652 VYLTYLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDR 716
            .:..:.|....|...|    :..::.||..::|.:..:..:|.......|:||..:: :...:.|
plant   831 AFECWKNAKGRGLSAE----FCSQYFVSPSAMKMLDQMRSQLESELKRHGIIPNDIS-SCSQNSR 890

  Fly   717 EKAIMLKVIIAGAFYPNYFTRSKESCADTDRNIYQTISG 755
            :..| |:.::|...|| ...|...:..:..|.|.:|.||
plant   891 DPGI-LRAVLAVGLYP-MVGRLCPAFGNNRRTIVETASG 927

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	201/720 (28%)
spn-E	NP_476741.1	TUDOR	892..1016	CDD:395449
HVT1	NP_850154.2	R3H_DEXH_helicase	22..80	CDD:100077
		HrpA	153..>946	CDD:224557	221/805 (27%)
		ANK repeat	417..444	CDD:293786	1/26 (4%)
		ANK repeat	446..481	CDD:293786	1/34 (3%)
		PTZ00322	453..>506	CDD:140343	7/52 (13%)
		ANK repeat	483..507	CDD:293786	5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820