Protein Alignment spn-E and dhx33

DIOPT Version :9

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001093527.3
• Gene: dhx33 / 796505
• ZFINID: ZDB-GENE-131127-77
• Length: 680
• Species: Danio rerio
• Alignment Length: 597
• Identity: 179/597 - (29%)
• Similarity: 286/597 - (47%)
• Gaps: 67/597 - (11%)

  Fly   113 KNLSIYAKREEILAAI-NAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAI 176
            ::|.||..|.::::.: ..|..|.| ||||.|||||:|||:.:...  |:...|.:|||||:|||
Zfish    45 RHLPIYQSRTQVISQLRQLHSAVFI-GETGSGKTTQIPQYLYEAGI--GRQGIIAITQPRRVAAI 106

  Fly   177 SIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVH 241
            |:|.||.:|::.|...:..:.|......|.| |:|.:.|.|:||...|.:..|..||.::|||.|
Zfish   107 SLAGRVAEEKKVQLGKLVGYTVRFEDVTSPE-TKLKFMTDGMLLREAIGDPLLLRYTVVILDEAH 170

  Fly   242 ERDQNMDFLLIVV----RRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHS 302
            ||..:.|.|..||    ||.|..|...:|:::||||:|....|.||..:    ||:.. ..|:|.
Zfish   171 ERTVHTDVLFGVVKAAQRRRLEQNKIPLKVVVMSATMDVDLFSQYFNKS----PVLYL-EGRQHP 230

  Fly   303 IEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGA 367
            |:.:|..|                |:.:   |..|..:.:.             |.:.||.....
Zfish   231 IQIYYTKQ----------------PQSD---YLQAALVSIF-------------QIHQEAPSSHD 263

  Fly   368 VLIFLPGIYEIDTMAENLTCMLENDPNI--KVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTN 430
            :|:||.|..||:.:|.....:.::.|:.  .:::|..::.:.|..|..||.|.|.|.||:||:||
Zfish   264 ILVFLTGQEEIEALARTCRDISKHLPDTSGSMTVVPLYASLPPAQQMRVFLPAPKGSRKVILSTN 328

  Fly   431 IAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNK 495
            |||:|||:..:.||||..:.|.|..:..|....|.:...|||...|||||.||..:|..||:..:
Zfish   329 IAETSITISGIKYVIDTGMVKAKRFNPDSGLEVLAVQRVSKAQAWQRAGRAGREDAGSCYRLYTE 393

  Fly   496 HFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALY 560
            ..:: .:....:||:.|..|.:.||  ::|.:|.|..:....:|.|:...:...:..|..:||:.
Zfish   394 DEFE-NLANMTVPEIQRCNLASVVL--QLLALGVPDVLNFDFVSKPSPESMRTAVEQLCILGAVD 455

  Fly   561 LTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGR 625
            ...|.:      .||..|..|:..||:.|.|:.:::...|:..||.:.|.:.||...:..:...|
Zfish   456 RKDDHV------SLTPLGKKMACFPLEPRFSKTLLISPDFSCTEEILTIISLLSVDSVLYNPPAR 514

  Fly   626 SQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLV 690
            .....|....:|.|:|....|:.|:|.:    ..|....|      |.:...|:.|::..:..:.
Zfish   515 RDEVISVRKKFISSEGDHITLLNIYRAF----KKVSGNKD------WCRENFVNSRNMGLVGEVR 569

  Fly   691 QELRVRCTHLGL 702
            .:||..|..:.|
Zfish   570 AQLRDICIKMNL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	177/590 (30%)
		TUDOR	892..1016	CDD:395449
dhx33	NP_001093527.3	DEXDc	50..234	CDD:214692	74/192 (39%)
		DEXDc	64..207	CDD:238005	62/146 (42%)
		Helicase_C	264..381	CDD:278689	44/116 (38%)
		HA2	451..536	CDD:214852	22/90 (24%)
		OB_NTP_bind	570..670	CDD:285018	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810