Protein Alignment spn-E and dhx38

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: XP_002937626.2
• Gene: dhx38 / 734019
• XenbaseID: XB-GENE-990308
• Length: 1212
• Species: Xenopus tropicalis
• Alignment Length: 911
• Identity: 221/911 - (24%)
• Similarity: 377/911 - (41%)
• Gaps: 221/911 - (24%)

  Fly    29 DPRLMATKFKSSEVPNRELIGTDYV-----SKIVAKEKCLLNGTLLNEQPQGKRI---------- 78
            |.|::.||.....:|.|:......:     |::|.|.:         ||.:.|:.
 Frog   402 DGRIVFTKQPEPVIPVRDATSDLAIIARKGSQLVRKHR---------EQKERKKAQHKHWELAGT 457

  Fly    79 ---------RTLDDLD-----------------TDDEGEETEIRRDDEYYKKFRFNLNRDKNLSI 117
                     :.:|:.|                 .|...|.:|...|   :.:.:..:.:.:.|.|
 Frog   458 KLGDIMGVKKQVDEPDKPIAEDGAVDYKAEQKFADHMRERSEASSD---FSRKKSLMEQRQYLPI 519

  Fly   118 YAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRV 182
            :|.::|:|..|..:.:||:.||||.|||||:.||:.::.|..  |..|..|||||:||:|:|.||
 Frog   520 FAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTD--YGMIACTQPRRVAAMSVAKRV 582

  Fly   183 CQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNM 247
            .:|.:........:.:......| |.|.:.|.|.|:||...:....|.||:.:::||.|||..|.
 Frog   583 SEEMQVSLGEEVGYAIRFEDCTS-EKTLIKYMTDGILLRECLREADLDHYSAVIMDEAHERSLNT 646

  Fly   248 DFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIP---------PVITTNHRRKHSI 303
            |.|..::|.:: |....:|:|:.|||:||.:.:.:|   .::|         ||
 Frog   647 DVLFGLLREVV-TRRSDLKLIVTSATMDADKFATFF---GNVPIFYIPGRTFPV----------- 696

  Fly   304 EKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAV 368
                            |:...:.|:  :....|||           |.|:|...|.    ..|.:
 Frog   697 ----------------DILFSKTPQ--EDYVEAAV-----------KQALQIHLSG----AAGDI 728

  Fly   369 LIFLPGIYEIDTMAENLTCMLEN-DPNIKVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIA 432
            |||:||..:|:..::.:...||. |....::::..:|.:..:.|..:|...|.|.||.|:.||||
 Frog   729 LIFMPGQEDIEVTSDQIVERLEELDSAPPLAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIA 793

  Fly   433 ESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHF 497
            |:|:||..:.:|||....|:||.:......:|::...|:||..||:||.||...|:.||:..:..
 Frog   794 ETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCYRLYTQSA 858

  Fly   498 YQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLT 562
            |:.|:....:||:.|..|.|.||..|  ::|....:|...:.||...::.|::..|..:|||..|
 Frog   859 YKNELLHTTVPEIQRTNLSNVVLLLK--SLGVQDLLLFHFMDPPPEDNMLNSMYQLWILGALDNT 921

  Fly   563 VDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQ 627
                     |.||..|.:|...|||...|:::|:........|.:|:.:.||.|.:|....||.:
 Frog   922 ---------GALTPTGRLMVEFPLDPALSKMLIVSCDMGCSSEILIVVSMLSVPAIFYRPKGREE 977

  Fly   628 LGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHV---SLRSLKEIHLL 689
            ..|.....:...:   ||       :|||||:.....:...:..|..:..:   ::|.::|:...
 Frog   978 ESDQVREKFAVPE---SD-------HLTYLNVFLQWKNNNYSSGWCNQHFIHAKAMRKVREVRAQ 1032

  Fly   690 VQELRVRCTHLGLIPFPVNPNQMMD----DREKAIMLKVIIAGAF-----------YPNYFTRSK 739
            ::::.|              :|.|.    ..:..|:.|.|.|..|           |.|  .|:.
 Frog  1033 LKDIMV--------------SQRMSLSSCGSDWDIVRKCICAAYFHQAARLKGIGEYVN--VRTG 1081

  Fly   740 ESCADTDRNIYQTIS----GHDPCRTVY-------------FTNFKPAYMGEL----YT------ 777
            ..|     :::.|.|    |:.|...||             .|.....::.||    |:
 Frog  1082 MPC-----HLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSIKHAGK 1141

  Fly   778 ------RRIKE----LFQEVRIPPENMDVTFQE----------GSQKVFVTFKQDDWIEGSSKYV 822
                  ||.||    :.:|:.:..|.:....:|          .|.|::...::|....|:.:..
 Frog  1142 TRQENRRRAKEEVSAMEEEMMLAEEQLRARREEQEKKNILSSARSLKIYTPGRKDQVEPGTPRRT 1206

  Fly   823 P 823
            |
 Frog  1207 P 1207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	170/595 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	66/188 (35%)
		TUDOR	892..1016	CDD:425754
dhx38	XP_002937626.2	HrpA	517..>1175	CDD:441249	197/750 (26%)