Protein Alignment spn-E and dhx9

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: XP_002937403.1
• Gene: dhx9 / 733723
• XenbaseID: XB-GENE-967775
• Length: 1257
• Species: Xenopus tropicalis
• Alignment Length: 905
• Identity: 260/905 - (28%)
• Similarity: 406/905 - (44%)
• Gaps: 183/905 - (20%)

  Fly    88 DEGE---------ETEIRRDDEYYKKFRFNLNRDKNL--------SIYAKR--EEILAAINAHPV 133
            |||.         ..|::.:..|:.       :|.|:        |:..|:  |||:.|::..||
 Frog   351 DEGPLAFAPQEQISAELKNEHMYHM-------QDPNMKQVLIDRESLPVKKFEEEIMHAVHNSPV 408

  Fly   134 VIIKGETGCGKTTQVPQYILDEAYKSGK--YCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSF 196
            |||:|.||||||||||||||||..::.:  .|||||||||||:|:|:|.||..||..:....|.:
 Frog   409 VIIRGATGCGKTTQVPQYILDECIRNDRAAQCNIVVTQPRRISAVSVAERVAFERGEEIGKSCGY 473

  Fly   197 QVG----LHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRL 257
            .|.    |.||::    .:|:||.||||..|  ...:...:|:::||:||||.|.||||:|:|.:
 Frog   474 SVRFESVLPRPHA----SMLFCTVGVLLRKL--EAGIRGISHVIVDEIHERDINTDFLLVVLRDV 532

  Fly   258 LATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYRD--QLGSII----- 315
            :.. ...:::||||||||.....:||...    |:|....|.....|.|..|  |:...|
 Frog   533 IQA-FPDIRVILMSATIDTSMFCEYFFNC----PIIEVFGRTFPVQEYFLEDCIQMTQFIPPPRD 592

  Fly   316 ----WNEEDVGHQQVPEIN-----KHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRY-GAVLI 370
                ..:|:.|..:....|     .:|......:..:.:.......|::...|.|.|.. ||||:
 Frog   593 KKKKDKDEEGGDDEETNCNLVCGDDYGPETRRSMSQLSEKETPLELIEALLKYIETLNVPGAVLV 657

  Fly   371 FLPGIYEIDTMAENLTCMLENDPNI---KVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIA 432
            ||||...|..|.::    ||.:|:.   ...|:...|.:..:.||.||:|.|.|..|:||:||||
 Frog   658 FLPGWNLIYAMQKH----LEMNPHFGSHSYCILPLHSQIPRDEQRKVFDPVPDGIIKVILSTNIA 718

  Fly   433 ESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHF 497
            |:|||:.||.||||.|..|||:..:.::.::....||||.|..||.||.||:|.|..:.:.::..
 Frog   719 ETSITINDVVYVIDSCKQKVKLFTSHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRAR 783

  Fly   498 YQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLT 562
            ::| :.....||:.|.||....|..|:|.:|...:.|:.|:.||.|..:......|:|:.||
 Frog   784 FER-LETHLTPEIFRTPLHEVALSIKLLRLGGIGQFLSKAIEPPPLDAVIEAEHTLRELDAL--- 844

  Fly   563 VDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQ 627
                 |..| :||..|.|:::||::.|..:::|:|.||.:.:....|:|....|..|..||.|
 Frog   845 -----DSND-ELTPLGRILAKLPIEPRLGKMMIMGCIFYVGDALCTISAATCFPEPFISEGRR-- 901

  Fly   628 LGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHV-SLRSLKEIHLLVQ 691
            ||   ::|..|:....||.||:..|:..:.:....|.:.|:.....||.:: :||...|..:.::
 Frog   902 LG---YVHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAETRFCEHKRLNMATLRMTWEAKVQLK 963

  Fly   692 ELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKV---------------IIAGAFYPNYFTRSKES 741
            |:.|..      .||          |:.:|.:|               ::|...|||.
 Frog   964 EILVNS------GFP----------EECLMTQVFNNTGPDNNLDVVISLLAFGVYPNV------- 1005

  Fly   742 CADTDRNIYQTISG-----HDPCRTVYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVT---- 797
            |...::....|..|     |.......|:|....|....:.  ..|..:...|..:.|.:.
 Frog  1006 CYHKEKRKILTTEGRNALIHKSSVNCPFSNQDLKYPSPFFV--FSEKIRTRAISAKGMTMVSPLQ 1068

  Fly   798 -FQEGSQKV-----FVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMRQNRVERPIHIMNPSAFM 856
             ....|:||     |:..  ||||                          |:..| |  :.||.:
 Frog  1069 LLLFASKKVMSDGEFILL--DDWI--------------------------RLSLP-H--DESACI 1102

  Fly   857 SYVQQRGIGDVIEGRWIPPTK---------PLNVELLALPSVFDKTISGSITCIVNCGKF 907
            :.::.     .:|...:..||         |:|.::|.:..:..|..:..|:.::...:|
 Frog  1103 TALRA-----ALEALVVEVTKEPEILSQLDPVNEKMLNMIRLISKPSTAGISLVMGNSRF 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	213/619 (34%)
		DEXHc_TDRD9	115..295	CDD:350746	85/195 (44%)
		TUDOR	892..1016	CDD:425754	3/16 (19%)
dhx9	XP_002937403.1	DSRM_DHX9_rpt1	3..71	CDD:380683
		DSRM_DHX9_rpt2	181..255	CDD:380684
		DEXHc_DHX9	333..565	CDD:350730	92/231 (40%)
		HrpA	388..>873	CDD:441249	184/509 (36%)
		HA2	840..921	CDD:214852	31/94 (33%)
		OB_NTP_bind	996..1075	CDD:400182	14/87 (16%)