Protein Alignment spn-E and Dhx35

DIOPT Version :9

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001359442.1
• Gene: Dhx35 / 71715
• MGIID: 1918965
• Length: 703
• Species: Mus musculus
• Alignment Length: 685
• Identity: 177/685 - (25%)
• Similarity: 307/685 - (44%)
• Gaps: 104/685 - (15%)

  Fly   102 YKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS-GKYCNI 165
            |........|.| |.::..|..||..:..:..|:|.|||||||:||:|||:.:..:.: |:.  :
Mouse    42 YAALSIEQQRQK-LPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRV--V 103

  Fly   166 VVTQPRRIAAISIANRVCQEREWQQNTVCSFQVG-LHRPNSLED---TRLLYCTTGVLLNNLINN 226
            .||||||:||:::|.||..||    ..|...:|| ..|.:...|   ||:.:.|.|:|:..::.:
Mouse   104 GVTQPRRVAAVTVAGRVADER----GAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVD 164

  Fly   227 KTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPP 291
            ..||.|:.|:|||.|||....|..:.:::::..... .:::|:.|||:||::..|:|....:..|
Mouse   165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRG-DLRLIVASATLDAEKFRDFFNQNETSDP 228

  Fly   292 -----VITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKA 351
                 |..|...|...::.||.              ...||:..|    |.|..:|.|...|..
Mouse   229 ARDTSVTLTVEGRTFPVDIFYL--------------QSPVPDYIK----ATVDTVVKIHQTEGD- 274

  Fly   352 AIQSRQSYDEALRYGAVLIFLPGIYEIDT----MAENLTCMLENDPNIKVSIVRCFSLMTPENQR 412
                          |.:|.||.|..|::|    :.|....:........:.::..::.:....|.
Mouse   275 --------------GDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQM 325

  Fly   413 DVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQR 477
            .||.......||:|:.||:||:|||:..:.||||....|::..:..::...|.:...|:|:..||
Mouse   326 KVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQR 390

  Fly   478 AGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPN 542
            |||.||.|||:.||:..:..:. ::|:..:|||.|..|...:|:.|.|.:.:.:..  ..:|||.
Mouse   391 AGRGGRNRSGKCYRLYTEEAFD-QLPQSTVPEMQRSNLAPVILQLKALGIDNVLRF--HFMSPPP 452

  Fly   543 LSDIHNTILLLKEVGAL----YLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNML 603
            ...:...:.||..:|.|    .||     :||       |..::..||:...:::::....|...
Mouse   453 AQSMVQALELLYALGGLDKDCRLT-----EPL-------GMRIAEFPLNPMFAKMLLESGNFGCS 505

  Fly   604 EEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQES 668
            :|.:.|||.:....:|....  :|...:..:|..|:...|.        :||.||:.|.......
Mouse   506 QEVLSIAAMMQIQNVFVFPS--NQKSQATRVHRKFAVEEGD--------HLTMLNVYEAFIKHNK 560

  Fly   669 AIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFYPN 733
            :.:|.:...::.:.|.....:..:|:..     |:.|.|  .::..:.:...:|:.|::| |:.|
Mouse   561 SSQWCQEHFLNYKGLVRAATVRDQLKKL-----LVKFQV--PKVSSEGDPDPVLRCIVSG-FFAN 617

  Fly   734 YFTRSKESCADTDRNIYQTI-SGHD----PCRTVY 763
             ..|...|.|      |:|| ..|:    |...:|
Mouse   618 -AARFHSSGA------YRTIRDDHELHIHPASVLY 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	158/601 (26%)
		TUDOR	892..1016	CDD:395449
Dhx35	NP_001359442.1	HrpA	21..682	CDD:224557	177/685 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810