Protein Alignment spn-E and Dhx38

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_848467.1
• Gene: Dhx38 / 64340
• MGIID: 1927617
• Length: 1228
• Species: Mus musculus
• Alignment Length: 731
• Identity: 202/731 - (27%)
• Similarity: 334/731 - (45%)
• Gaps: 128/731 - (17%)

  Fly     5 VMDFFD----FSKELKRVAAAPQGYISSDPRLMATKFKSSEVPNR-------------ELIGTDY 52
            |..|.|    |:|:.:.|  .|....:||..::|.|...:...:|             ||.||.
Mouse   414 VPPFLDGRIVFTKQPEPV--IPVKDATSDLAIIARKGSQTVRKHREQKERRKAQHKHWELAGTK- 475

  Fly    53 VSKIVAKEKCLLNGTLLNEQP------QGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLNR 111
            :..|:..:|        .|:|      .||.....:....|...|::|  ...|:.|| :..|.:
Mouse   476 LGDIMGVKK--------EEEPDKAMTEDGKVDYRTEQKFADHMKEKSE--ASSEFAKK-KSILEQ 529

  Fly   112 DKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAI 176
            .:.|.|:|.::|:|..|..:.:||:.||||.|||||:.||:.::.|..  |..|..|||||:||:
Mouse   530 RQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTD--YGMIGCTQPRRVAAM 592

  Fly   177 SIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVH 241
            |:|.||.:|..........:.:......| |:|.:.|.|.|:||...:....|.||:.:::||.|
Mouse   593 SVAKRVSEEMGGNLGEEVGYAIRFEDCTS-ENTLIKYMTDGILLRESLREADLDHYSAVIMDEAH 656

  Fly   242 ERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIP---------PVITTNH 297
            ||..|.|.|..::|.::|..| .:|:|:.|||:||::.:.:|   .::|         ||
Mouse   657 ERSLNTDVLFGLLREVVARRS-DLKLIVTSATMDAEKFAAFF---GNVPIFHIPGRTFPV----- 712

  Fly   298 RRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEA 362
                                  |:...:.|:  :....||||              ||.|.:...
Mouse   713 ----------------------DILFSKTPQ--EDYVEAAVK--------------QSLQVHLSG 739

  Fly   363 LRYGAVLIFLPGIYEI----DTMAENLTCMLENDPNIKVSIVRCFSLMTPENQRDVFNPPPPGFR 423
            .. |.:|||:||..:|    |.:.|:|. .|||.|  .::::..:|.:..:.|..:|...|.|.|
Mouse   740 AP-GDILIFMPGQEDIEVTSDQIVEHLE-ELENAP--ALAVLPIYSQLPSDLQAKIFQKAPDGVR 800

  Fly   424 KIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGR 488
            |.|:.|||||:|:||..:.:|||....|:||.:......:|::...|:||..||:||.||...|:
Mouse   801 KCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQ 865

  Fly   489 VYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLL 553
            .:|:..:..|:.|:....:||:.|..|.|.||..|.|.:...::.  ..:.||...::.|::..|
Mouse   866 CFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQF--HFMDPPPEDNMLNSMYQL 928

  Fly   554 KEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGL 618
            ..:|||..|         |.||..|.:|...|||...|:::|:........|.::|.:.||.|.:
Mouse   929 WILGALDNT---------GGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAI 984

  Fly   619 FAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHV---SL 680
            |....||.:..|.....:...:   ||       :|||||:.....:...:..|.....:   ::
Mouse   985 FYRPKGREEESDQIREKFAVPE---SD-------HLTYLNVYLQWKNNNYSTIWCNDHFIHAKAM 1039

  Fly   681 RSLKEIHLLVQELRVR 696
            |.::|:...::::.|:
Mouse  1040 RKVREVRAQLKDIMVQ 1055

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	173/599 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	67/188 (36%)
		TUDOR	892..1016	CDD:425754
Dhx38	NP_848467.1	HrpA	533..>1147	CDD:441249	173/598 (29%)