Protein Alignment spn-E and dhx9

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001188373.1
• Gene: dhx9 / 568043
• ZFINID: ZDB-GENE-070912-171
• Length: 1270
• Species: Danio rerio
• Alignment Length: 810
• Identity: 255/810 - (31%)
• Similarity: 390/810 - (48%)
• Gaps: 150/810 - (18%)

  Fly    88 DEGEE---TEIRRDDEYYKKFRFNLNRDKNL-SIYAKR---------EEILAAINAHPVVIIKGE 139
            |||..   |..:..::...:..:.|.:|:|| :|..:|         |:|::.|..:|||||:|.
Zfish   355 DEGPLAFCTPEQISNDLLNELNYQLEQDQNLQTILTERSQLPVKNFQEQIMSTIYNNPVVIIRGA 419

  Fly   140 TGCGKTTQVPQYILDEAYKSGKY--CNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVG--- 199
            ||||||||||||||||..|.|:.  |||||||||||:|:|:|.||..||.......|.:.|.
Zfish   420 TGCGKTTQVPQYILDEFIKGGRASDCNIVVTQPRRISAVSVAERVSFERGEDVGKSCGYSVRFES 484

  Fly   200 -LHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSR 263
             |.||::    .:|:||.||||..|  ...:...:|:::||:||||.|.||||:|:|.::....
Zfish   485 FLPRPHA----SILFCTVGVLLRKL--ESGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYP- 542

  Fly   264 HVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFY--------------------- 307
            .|::||||||||.....:||...    |||.. |.|.|.:::::
Zfish   543 DVRVILMSATIDTTMFKEYFFNC----PVIEV-HGRAHPVQEYFLEDCIQMTQFVPPPMDRKRKD 602

  Fly   308 RDQLGSIIWNEEDV------GHQQVPEINKHGYRAAVKIIVIIDNMERKAA----IQSRQSYDEA 362
            :|..|    .:|||      |.:..||..:           .:..:..|..    |::...|.|.
Zfish   603 KDDEG----GDEDVNCNVICGSEYSPETKR-----------AMSQLNEKETSFELIEALLKYIET 652

  Fly   363 LRY-GAVLIFLPGIYEIDTMAENLTCMLENDPNI---KVSIVRCFSLMTPENQRDVFNPPPPGFR 423
            |.. ||||:||||...|.:|.::    ||.:|:.   :..|:...|.:..|.||.||.|.|.|..
Zfish   653 LEVPGAVLVFLPGWNLIYSMQKH----LEMNPHFGGHQYRILPLHSQIPREEQRRVFEPVPDGVT 713

  Fly   424 KIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGR 488
            |:||:|||||:|||:.||.:|:|.|..|||:..:.::.::....||||.|..||.||.||:|.|.
Zfish   714 KVILSTNIAETSITINDVVFVLDSCKQKVKLFTSHNNMTNYATVWASKTNLEQRKGRAGRVRPGF 778

  Fly   489 VYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLL 553
            .:.:.::..::: :.....||:.|.||....|..|:|.:|.....|:.|:.||.|..:......|
Zfish   779 CFHLCSRARFEK-LETHMTPEIFRTPLHEVALSIKLLRLGGIGNFLSKAIEPPPLDAVIEAEHTL 842

  Fly   554 KEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGL 618
            :|:.||        |..| :||..|.|:::||::.|..:::|:|.|||:.:....|:|....|..
Zfish   843 RELDAL--------DSND-ELTPLGRILAKLPIEPRLGKMMIMGCIFNVGDAVCTISAATCFPEP 898

  Fly   619 FAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHV-SLRS 682
            |..||.|  ||   ::|..|:....||.||:..|:..:..:...|.|.|......||.:: :||.
Zfish   899 FISEGKR--LG---FVHRNFAGSRFSDHVALLSVFQAWDEVRVGGEDAEIRFCEHKRLNMPTLRM 958

  Fly   683 LKEIHLLVQELRVRCTHLGLIPFP-----------VNPNQMMDDREKAIMLKVIIAGAFYPN--Y 734
            ..|..:.::|:.|.      :.||           |.|:..:|     :::.::..|: |||  |
Zfish   959 TWEAKVQLKEILVN------VGFPEECLLNQVFNNVGPDNNLD-----LVISLLTFGS-YPNVCY 1011

  Fly   735 FTRSKESCADTDRN--IYQT-----ISGHD---PCRTVYFTNFKPAYMGELYTRRIKELFQEVRI 789
            ....::......||  |:::     .|.||   |.....|        ||....|.........:
Zfish  1012 HKEKRKILTTEGRNALIHKSSVNCPFSNHDLKYPSPFFVF--------GEKIRTRAISAKSMTLV 1068

  Fly   790 PPENMDVTFQEGSQKVF---VTFKQDDWIE 816
            .|..: :.|  ||:|:.   ...:.||||:
Zfish  1069 SPLQL-ILF--GSKKITSNGEVVELDDWIK 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	219/634 (35%)
		DEXHc_TDRD9	115..295	CDD:350746	89/195 (46%)
		TUDOR	892..1016	CDD:425754
dhx9	NP_001188373.1	DSRM_DHX9_rpt1	3..71	CDD:380683
		DSRM_DHX9_rpt2	185..259	CDD:380684
		DEXHc_DHX9	337..570	CDD:350730	96/225 (43%)
		HrpA	387..>892	CDD:441249	192/545 (35%)
		OB_NTP_bind	1000..1079	CDD:400182	19/90 (21%)