Protein Alignment spn-E and dhx34

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001121805.1
• Gene: dhx34 / 555838
• ZFINID: ZDB-GENE-061207-30
• Length: 1150
• Species: Danio rerio
• Alignment Length: 886
• Identity: 228/886 - (25%)
• Similarity: 371/886 - (41%)
• Gaps: 226/886 - (25%)

  Fly    77 RIRTLDDLDTDDE---GEETEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKG 138
            |:..|..||.:.:   .:.:::||:             .|:|.|:..|::|:..:..||||::.|
Zfish   134 RLALLHFLDFNQKQSFSKLSKLRRE-------------QKSLPIFQYRDKIVELVRTHPVVVVAG 185

  Fly   139 ETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRP 203
            :|||||:||||||:|.....     ||..|||||||.||:|.||..|...|..:...:|:.....
Zfish   186 DTGCGKSTQVPQYLLASGIN-----NIACTQPRRIACISLAKRVSFESLNQYGSKVGYQIRFETS 245

  Fly   204 NSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKII 268
            .:|. |:||:.|.|:||..:..:.:|..|..:::||||||..:.||||.|:|.||:... .::::
Zfish   246 RTLA-TKLLFLTEGLLLRQIQQDASLGQYQVLIVDEVHERHLHCDFLLGVLRSLLSLRP-DLRLV 308

  Fly   269 LMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHG 333
            ||||||:.|..|.||...    ||:.. ..|...|:..|:.     |..||     ||....|..
Zfish   309 LMSATINIKLFSSYFNDA----PVLQV-PGRLFPIQVIYQP-----IPPEE-----QVSRSEKLD 358

  Fly   334 YRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVS 398
            .|..::::..||           |.|.:..| |.:|:||.|:.||.|:.|  .|........:..
Zfish   359 PRPYLRVLQGID-----------QRYPQEER-GDLLLFLSGVAEISTIQE--ACQTYATHTQRWI 409

  Fly   399 IVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSS 463
            ::...|.::...|..||:..|||.||.|::|||||:|:|:..|.:|:|....|....|..:....
Zfish   410 VLPLHSTLSLAQQDKVFDIAPPGVRKCIISTNIAETSVTIDGVRFVVDSGKVKEMSFDPKAKMQR 474

  Fly   464 LRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMG 528
            |:..|.|:|:..||.||.||...|..||:.::..|....| :.:||:.|:.|.:.:|:.|.:.:|
Zfish   475 LQEFWISRASSEQRKGRAGRTGPGVCYRLYSESDYDAFAP-YPVPEIHRVALDSLILQMKSMGLG 538

  Fly   529 SPVEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRL 593
            .|...  ..:.||..|.|...:..|:|.|||         ...|:||..|.::::||:|....::
Zfish   539 DPRTF--TFIDPPPASSIQTAVTYLREQGAL---------DEHGELTSIGRLLAQLPVDVVIGKM 592

  Fly   594 IILGYIFNMLEEAIIIAAGLSTPGLF------------AHEGGRSQLGDSF--------WMHYIF 638
            ::||.:||::|..:.:||.||....|            |.:...|..||.|        |:....
Zfish   593 LVLGSVFNLVEPVLTVAAALSVQSPFLRSAQHNPDCSTARQPLNSNHGDPFTLMNTFNAWVQVKA 657

  Fly   639 SDGSGS---------------DLVAIWRVYLTYL---NIVEN----GHDQESAIRWAKRF--HVS 679
            ..||||               ::|.:.|.:...|   .::|:    ..:.:...|..:||  ...
Zfish   658 DRGSGSRKWCRRRGLEEQRLYEMVNLRRQFKELLRSHGLLEDDTGRATEPQDRARRRERFTERQK 722

  Fly   680 LRSLKEIHLL--------------------------------------------VQELRVRCTHL 700
            |..||..|.|                                            :||::.:..|
Zfish   723 LHQLKRDHELQENTKRKVLRLEEGLEGDASSGSDAEESSTSRKKRKDGAEQTMDIQEVKFKLRH- 786

  Fly   701 GLIPFPVNPNQMMDDRE--------KAIMLKVIIAGAFYPN-----------------YFTRSKE 740
                   |.|::.:...        :..:||:::....||.                 :.||:|:
Zfish   787 -------NVNELQESAYASAALSSLQQALLKLLLCRGLYPQLAIPDEHNATRKDSDQVFHTRNKQ 844

  Fly   741 SCADTDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVTFQEGSQK- 804
            .......:::.:    ||                           ||...||:....|.:.::.
Zfish   845 GVVIHPTSVFAS----DP---------------------------EVLHVPEHETSEFGQSNRHQ 878

  Fly   805 --VFVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMRQNRV 843
              .|||.     :|.:..|  :|..|:....:|:::..|.|
Zfish   879 LLAFVTL-----LETNKPY--LSNCVRVPALQALLLVANSV 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	194/670 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	74/179 (41%)
		TUDOR	892..1016	CDD:425754
dhx34	NP_001121805.1	HrpA	161..>622	CDD:441249	170/508 (33%)
		OB_NTP_bind	814..910	CDD:400182	20/133 (15%)