Protein Alignment spn-E and bgcn

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Alignment Length: 799
• Identity: 162/799 - (20%)
• Similarity: 290/799 - (36%)
• Gaps: 226/799 - (28%)

  Fly   122 EEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQER 186
            :|||.::.|..|::........|:..:|..|||:.  ..|..|:.:....|.|.::..|
  Fly   155 DEILQSLYASRVIVYNAALCWDKSVFLPLVILDDC--RNKKSNVKIMCIERQAILATYN------ 211

  Fly   187 EWQQNTVCSF------QVGLHRP---NSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHE 242
              .|.|...|      .||:..|   .....|.::|.|....|.:| .::...:.:|:|:::||.
  Fly   212 --SQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSL-TSQQFRNISHLVVNDVHL 273

  Fly   243 RDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYF------------------------ 283
            .|...|.||..:|..|::: ::::::|:|...:.|:.:|:|
  Fly   274 HDPYTDILLSEIRMALSSH-QNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNEL 337

  Fly   284 -------------TTTNSIPPVITTNHRRKHSIEKFYR--DQLG----------SIIWNEEDVGH 323
                         .....||.....|:.|...::|..:  .:||          ::.::...|.:
  Fly   338 HSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNY 402

  Fly   324 QQ----------VPEINK---------------------------------------------HG 333
            :.          ..|:||                                             ||
  Fly   403 RHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHG 467

  Fly   334 Y--RAA----VKIIVIIDNMERKAAIQSRQSYDEALRY--GAVLIFLPGIYEIDTMAENLTCMLE 390
            |  ::|    |...:|||.|   ..::::..|... .|  |.:||.||..|.|    ..|..|:.
  Fly   468 YVVKSAKPDFVDYDLIIDIM---YLLRTKPEYSPG-EYSPGNILIILPTYYHI----VKLNYMIL 524

  Fly   391 NDPNIKVSIVRCFSLMTPENQRD-----VFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLA 450
            :. .:..|:..|...:..:|.|:     :.|...... |::|.|:|.||........|.||....
  Fly   525 SH-CLTGSLQECSIFLLYDNMRNDYLQALVNASDETV-KVVLATDIIESLCLKVPFKYQIDTACR 587

  Fly   451 KVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRV--YRMVNKHFYQREMPEFGIPEMLRL 513
            ...|.||.|.....|..|.:| :...|...:.:...|.|  :|:::|..|: |:.|...|.:..:
  Fly   588 LNNVYDTTSCSGDDRFEWVAK-DALLRRELILQPNKGDVQCFRLISKEAYE-ELSETSQPSLQTM 650

  Fly   514 PLQNSVLKAKVLNMGSPV-EILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDG--DLT 575
            .|....|..|:|:..:.: |.|.:.:|||.|.::|:.:..||::           |.||.  |:|
  Fly   651 QLDKICLAVKLLSPNTIISEYLGITISPPPLINVHHAVQFLKKI-----------DVLDDAEDVT 704

  Fly   576 YWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQLG-------DSFW 633
            :.|..:..:|:..:..|::|.|.:...|:..:.|.:.|||         ...||       |:.|
  Fly   705 WLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLST---------ADPLGIPFTEDIDNLW 760

  Fly   634 MHY-------------IFSDGSGSDLVAIWRVYLTYLNIVEN-------GHDQESAIRWAKRFHV 678
            ..:             ..||...||.....|:|..:.|.:.|       ..:.|..:........
  Fly   761 DRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLT 825

  Fly   679 SLR-----SLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFYPNYFTRS 738
            |:|     ||:..:|:....::...:|         |||..:..   |:|..:.|..|||.:
  Fly   826 SIRSEIVSSLRAANLIHSRGKLSMNNL---------NQMSCNWH---MVKAALTGGMYPNIY--- 875

  Fly   739 KESCADTDR-NIYQTISGH 756
               ..||.: ::....||:
  Fly   876 ---AVDTRKSSLKSAFSGN 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	148/737 (20%)
		DEXHc_TDRD9	115..295	CDD:350746	43/218 (20%)
		TUDOR	892..1016	CDD:425754
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	40/170 (24%)
		ANKYR	<398..>460	CDD:440430	4/61 (7%)
		ANK repeat	406..438	CDD:293786	3/31 (10%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	35/138 (25%)
		HA2	687..789	CDD:461295	25/121 (21%)
		OB_NTP_bind	862..945	CDD:400182	9/36 (25%)