Protein Alignment spn-E and pea

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 199/723 - (27%)
• Similarity: 322/723 - (44%)
• Gaps: 141/723 - (19%)

  Fly   103 KKFRFNLNRD-------KNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS- 159
            ||..|....|       ::|.||..|::::.|:..:.::|:.||||.|||||:.||:.:..:.:
  Fly   567 KKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTAR 631

  Fly   160 GKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLI 224
            ||   |..|||||:||:|:|.||.:|...:......:.:......|.| |.:.|.|.|:||...:
  Fly   632 GK---IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPE-TIIKYMTDGMLLRECL 692

  Fly   225 NNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSR-HVKIILMSATIDAKELSDYFTTTNS 288
            ....|..|:.|:|||.|||..:.|.|..:::  .|...| .:|:|:.|||:||.:.|.||...
  Fly   693 MEAELKSYSVIMLDEAHERTIHTDVLFGLLK--TAVQKRPELKLIVTSATLDAVKFSQYFFKA-- 753

  Fly   289 IPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAI 353
              |:.|. ..|...:|..|..:                ||.:   |..|..|.|:..::....
  Fly   754 --PIFTI-PGRTFPVEVLYTKE----------------PETD---YLDASLITVMQIHLREPP-- 794

  Fly   354 QSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLEN-DPNI-KVSIVRCFSLMTPENQRDVFN 416
                        |.:|:||.|..||||..|.|...::: .|:: ::.|:..:|.:..|.|..:|:
  Fly   795 ------------GDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFD 847

  Fly   417 PPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRV 481
            |.|.|.||:::.|||||:|:|:..:.||:|....|.||.::.:...||.:|..|:|..:|||||.
  Fly   848 PAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRA 912

  Fly   482 GRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGS----------PVEILAL 536
            ||...|:.||:..:..|:.||....:||:.|..|..:||:.|.:.:..          |||.|.:
  Fly   913 GRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVM 977

  Fly   537 ALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFN 601
            |     |..:|:...|..|                |.||..|..|:..||:...|:::|:.....
  Fly   978 A-----LEQLHSLSALDDE----------------GLLTRLGRRMAEFPLEPNLSKMLIMSVALQ 1021

  Fly   602 MLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQ 666
            ..:|.:.|.:.||...:|.....:..|.|.....:..::|.          :||.|.:..:..:.
  Fly  1022 CSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGD----------HLTLLAVYNSWKNN 1076

  Fly   667 ESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFY 731
            :.:..|.....|.:|:||.    .|::|.:.  ||::           ||.|   |.|:.||
  Fly  1077 KFSNAWCYENFVQIRTLKR----SQDVRKQL--LGIM-----------DRHK---LDVVSAG--- 1118

  Fly   732 PNYFTRSKESCADTDRNI--------YQTISGHDPCRTVY------FTNFKPAYMGELY---TRR 779
            .|.....|..|:...||.        |:|:.   ..:.||      ..|.:|.::  :|   .:.
  Fly  1119 KNSVRIQKAICSGFFRNAAKKDPQEGYRTLV---DSQVVYIHPSSALFNRQPEWV--IYHELVQT 1178

  Fly   780 IKELFQEV 787
            .||..:||
  Fly  1179 TKEYMREV 1186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	170/596 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	64/181 (35%)
		TUDOR	892..1016	CDD:425754
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	195/712 (27%)