Protein Alignment spn-E and Dhx35

DIOPT Version :9

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: XP_006235485.1
• Gene: Dhx35 / 362260
• RGDID: 1311165
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 647
• Identity: 171/647 - (26%)
• Similarity: 295/647 - (45%)
• Gaps: 91/647 - (14%)

  Fly   102 YKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS-GKYCNI 165
            |........|.| |.::..|..||..:..:..|:|.|||||||:||||||:.:..:.: |:.  :
  Rat    42 YAALSIEQQRQK-LPVFKLRNHILYLVENYQTVVIVGETGCGKSTQVPQYLAEAGWTAEGRV--V 103

  Fly   166 VVTQPRRIAAISIANRVCQEREWQQNTVCSFQVG-LHRPNSLED---TRLLYCTTGVLLNNLINN 226
            .||||||:||:::|.||..||    ..|...:|| ..|.:...|   ||:.:.|.|:|:..::.:
  Rat   104 GVTQPRRVAAVTVAGRVADER----GAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVD 164

  Fly   227 KTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPP 291
            ..||.|:.::|||.|||....|..:.:::::..... .:::|:.|||:||::..|:|....:..|
  Rat   165 PLLTKYSVVMLDEAHERTLYTDIAIGLLKKIQKKRG-DLRLIVASATLDAEKFRDFFNQNETSDP 228

  Fly   292 -----VITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKA 351
                 ||.|...|...::.||.              ...||:..|    |.|..:|.|...|..
  Rat   229 ARDTCVILTVEGRTFPVDIFYL--------------QSPVPDYIK----ATVDTVVKIHQTEGD- 274

  Fly   352 AIQSRQSYDEALRYGAVLIFLPGIYEIDT----MAENLTCMLENDPNIKVSIVRCFSLMTPENQR 412
                          |.:|.||.|..|::|    :.|....:........:.::..::.:....|.
  Rat   275 --------------GDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQM 325

  Fly   413 DVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQR 477
            .||.......||:|:.||:||:|||:..:.||||....|::..:..::...|.:...|:|:..||
  Rat   326 KVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQR 390

  Fly   478 AGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPN 542
            |||.||.|||:.||:..:..:: ::|:..:|||.|..|...||:.|.|.:.|.:..  ..:|||.
  Rat   391 AGRGGRNRSGKCYRLYTEEAFE-QLPQSTVPEMQRSNLAPVVLQLKALGIDSVLRF--HFMSPPP 452

  Fly   543 LSDIHNTILLLKEVGAL----YLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNML 603
            ...:...:.||..:|.|    .||     :||       |..::..||:...:::::....|...
  Rat   453 AQSMVQALELLYALGGLDKDCRLT-----EPL-------GMRIAEFPLNPMFAKMLLESGNFGCS 505

  Fly   604 EEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQES 668
            :|.:.|||.:....:|....  :|...:..:|..|:...|.        :||.||:.|.......
  Rat   506 QEILSIAAMMQIQNVFVFPS--NQKSQATRVHRKFAVEEGD--------HLTMLNVYEAFIKHNK 560

  Fly   669 AIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAF 730
            :.:|.:...::.:.|.....:..:|:..     |:.|.|  .:|..:.:...:|:.|::|.|
  Rat   561 SSQWCQEHFLNYKGLVRAATVRDQLKKL-----LVKFQV--PKMSSEGDPDPVLRCIVSGFF 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	161/601 (27%)
		TUDOR	892..1016	CDD:395449
Dhx35	XP_006235485.1	DEXDc	53..224	CDD:214692	62/178 (35%)
		DEXDc	73..211	CDD:238005	52/144 (36%)
		HELICc	301..396	CDD:197757	26/94 (28%)
		HA2	465..549	CDD:214852	21/105 (20%)
		OB_NTP_bind	584..683	CDD:285018	9/39 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810