Protein Alignment spn-E and l(2)37Cb

DIOPT Version :9

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 670
• Identity: 187/670 - (27%)
• Similarity: 307/670 - (45%)
• Gaps: 98/670 - (14%)

  Fly    82 DDLD-----TDDEGEETEIRRDDEYYKKFRFNLNRD---KNLSIYAKREEILAAINAHPVVIIKG 138
            |.:|     |.|...|....|..|..:|.|..|..|   ::|.:|..:|:::||:..|.|:||:|
  Fly   211 DQIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEG 275

  Fly   139 ETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRP 203
            |||.|||||||||:::..:...|.. |..|||||:||:|:|.||.:|...:......:.:.....
  Fly   276 ETGSGKTTQVPQYLVEAGFTKDKKM-IGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDC 339

  Fly   204 NSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKII 268
            .| :.|.|.|.|.|.|....::...|..|:.:::||.|||..:.|.|..:|:. :|.....:|::
  Fly   340 TS-DRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKD-IARFRPELKLL 402

  Fly   269 LMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHG 333
            :.|||:||::.|.:|...    |:.....|| :.::.||                .:.||.:
  Fly   403 ISSATLDAEKFSAFFDDA----PIFRIPGRR-YPVDIFY----------------TKAPEAD--- 443

  Fly   334 YRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLEN-DPNIK- 396
            |..|..:.|:        .|.:.|.      .|.:|:||.|..||:|..|.|...::. ...|:
  Fly   444 YIDACCVSVL--------QIHATQP------LGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRE 494

  Fly   397 VSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSF 461
            :.::..::.:..:.|..:|.|.||..||:||.|||||:|:|:.::.||||...||....::.:..
  Fly   495 LIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGM 559

  Fly   462 SSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLN 526
            .||.:...|||:..|||||.||...|:.:|:.....|:.|:.:..:||:.|:.|.|:||..|.|.
  Fly   560 ESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALG 624

  Fly   527 MGSPVEILALALSPPNLSDIHNTILLLKE----VGALYLTVDGIYDPLDGDLTYWGTIMSRLPLD 587
            :...:..  ..|.||.    |.|::|..|    :|||         ...|:||..|..|:..|:|
  Fly   625 INDLIHF--DFLDPPP----HETLVLALEQLYALGAL---------NHHGELTKLGRRMAEFPVD 674

  Fly   588 TRQSRLIILGYIFNMLEEAIIIAAGLS-TPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWR 651
            ....::::....:...||.:.|||.|| ...:|.....:....|:...::....|.
  Fly   675 PMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGD--------- 730

  Fly   652 VYLTYLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLVQEL-----RVRCTHLGLIPFPVNPNQ 711
             :|:.|.:.....:.:.:.:|.....:..||:|....:.::|     ||....:..:|..||
  Fly   731 -HLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETVN--- 791

  Fly   712 MMDDREKAIMLKVIIAGAFY 731
                     :.|...||.||
  Fly   792 ---------VRKAATAGYFY 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	168/595 (28%)
		TUDOR	892..1016	CDD:395449
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	184/659 (28%)
		DEXDc	269..408	CDD:238005	51/141 (36%)
		HELICc	491..581	CDD:197757	33/89 (37%)
		HA2	651..735	CDD:214852	21/102 (21%)
		OB_NTP_bind	770..869	CDD:285018	11/45 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840