Protein Alignment spn-E and dhx15

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001108613.1
• Gene: dhx15 / 321931
• ZFINID: ZDB-GENE-030131-650
• Length: 769
• Species: Danio rerio
• Alignment Length: 750
• Identity: 207/750 - (27%)
• Similarity: 331/750 - (44%)
• Gaps: 144/750 - (19%)

  Fly    93 TEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILD--- 154
            |.:.....||:..:..|    .|.::..:|.....:|.|...::.||||.|||||:||:.:|
Zfish    93 TNLPHTPRYYEILKKRL----QLPVWEYKERFNDILNRHQSFVLVGETGSGKTTQIPQWCVDMVR 153

  Fly   155 --EAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTG 217
              ...|.|..|    |||||:||:|:|.||..|.:........:.:.....:|.: |.|.|.|.|
Zfish   154 SLPGPKRGVAC----TQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAK-TILKYMTDG 213

  Fly   218 VLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDY 282
            :||...:|:..|..|..|:|||.|||....|.|:.|::.::...| .:|:|:||||:||.:...|
Zfish   214 MLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRS-DLKVIVMSATLDAGKFQVY 277

  Fly   283 FTTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNM 347
            |...    |::|. ..|.|.:|.||                  .||..:....||::.::.|...
Zfish   278 FDNC----PLLTI-PGRTHPVEIFY------------------TPEPERDYLEAAIRTVIQIHMC 319

  Fly   348 ERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLEN-DPNI-KVSIVRCFSLMTPEN 410
            |.          ||    |.||:||.|..|||...:.:...::: .|:: .:.|:..:|.:.|:.
Zfish   320 EE----------DE----GDVLLFLTGQEEIDEACKRIKREIDDLGPDVGDIKIIPLYSTLPPQQ 370

  Fly   411 QRDVFNPPPP-------GFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTW 468
            |:.:|.||||       | ||::::|||||:|:|:..|.:|||...||.||.:......||.:|.
Zfish   371 QQRIFEPPPPRKPNGAIG-RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTA 434

  Fly   469 ASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEI 533
            .|||:.:|||||.||.|.|:.:|:..:..|:.||.:...||:||..|.:.||:.|.|.:...|..
Zfish   435 ISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF 499

  Fly   534 LALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGY 598
              ..:.||....:...:.||..:.||       .|  |||||..|::|:..|||.:.::::|...
Zfish   500 --DFMDPPAPETLMRALELLNYLAAL-------ND--DGDLTELGSMMAEFPLDPQLAKMVIASC 553

  Fly   599 IFNMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENG 663
            .||...|.:.|.|.||.|..|.......:..|...|.:...||.          :||.||:....
Zfish   554 DFNCSNEVLSITAMLSVPQCFVRPTEAKKAADESKMRFAHIDGD----------HLTLLNVYHAF 608

  Fly   664 HDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMD------------DR 716
            .....:::|.....::.|||.....:.|:|                :::||            .|
Zfish   609 KQNHESVQWCYDNFINYRSLMSADNVRQQL----------------SRIMDRFNLPRRSTEFTSR 657

  Fly   717 EKAIMLKVIIAGAFYPN--YFTRSKESCADTDRNIYQ----TISGHDPCRTVY------------ 763
            :..|.::..:...|:..  :..|:.......|..:.|    |:..|.|...:|
Zfish   658 DYYINIRRALVTGFFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIR 722

  Fly   764 -FTNFKPAYMGELYTRRIKELFQEVRIPPENMDVT 797
             .|:.||.::              |:|.|:..:::
Zfish   723 TCTDIKPEWL--------------VKIAPQYYEMS 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	185/596 (31%)
		DEXHc_TDRD9	115..295	CDD:350746	64/184 (35%)
		TUDOR	892..1016	CDD:425754
dhx15	NP_001108613.1	HrpA	110..>737	CDD:441249	202/721 (28%)