Protein Alignment spn-E and mog-1

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_499212.1
• Gene: mog-1 / 176409
• WormBaseID: WBGene00003389
• Length: 1131
• Species: Caenorhabditis elegans
• Alignment Length: 917
• Identity: 233/917 - (25%)
• Similarity: 389/917 - (42%)
• Gaps: 191/917 - (20%)

  Fly     1 MDQEVMDFFDFSKELKRVAAAPQGYISS--DPRLMATK--------------------------F 37
            |..|:...|:...:..||....|..:..  |.|::.||                          .
 Worm   298 MADELSSIFEDETDENRVTILVQNIVPPFLDGRIVFTKQAQPIIPVVDTTCDMAVSAARGSVAVR 362

  Fly    38 KSSEVPNR--------ELIGTDYVSKIVAKEKCLLNGTLLNEQPQGKRIRTLDDLDTDDEGEETE 94
            |..||.:|        ||.|:...:.:..||               |:..|.|..| ||.|...|
 Worm   363 KRREVEDRKKAQDKHWELAGSKLGNLMGVKE---------------KKDETADPED-DDSGNYKE 411

  Fly    95 IR------RDDEYYKKFRFNLN---RDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQ 150
            ..      :|:|....|....:   :.:.|.::|.|::::..|..:.||||.||||.|||||:.|
 Worm   412 SHQFASHMKDNEAVSDFAMEKSIKQQREYLPVFACRQKMMNVIRENNVVIIVGETGSGKTTQLAQ 476

  Fly   151 YILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCT 215
            |:|::.:  |....|..|||||:||:|:|.||..|..........:.:......| |.|.:.|.|
 Worm   477 YLLEDGF--GDSGLIGCTQPRRVAAMSVARRVADEMGVDLGQDVGYAIRFEDCTS-EKTIIKYMT 538

  Fly   216 TGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELS 280
            .|:||...:.:.:|..|:.|::||.|||..|.|.|..::|.::|..: .:|:|:.|||:||.:.:
 Worm   539 DGILLRECLGDGSLDQYSAIIMDEAHERSLNTDVLFGLLREVIAKRA-DLKLIVTSATMDADKFA 602

  Fly   281 DYF---TTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVK--I 340
            |:|   ..|.:||       .|...:|.|                |.:.|.  :....||||  :
 Worm   603 DFFGGNCPTFTIP-------GRTFPVELF----------------HARTPV--EDYVDAAVKQAV 642

  Fly   341 IVIIDNMERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCML-ENDPNIKVSIVRCFS 404
            .:.:..|:                 |.:|||:||..:|:...|.:...| |.|....::::..:|
 Worm   643 TIHLGGMD-----------------GDILIFMPGQEDIECTCEMIKEKLGELDEAPPLAVLPIYS 690

  Fly   405 LMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVID--FCLAKVKVTDTASSFSSLRLT 467
            .:..:.|..:|...|.|.||.|:.|||||:|:||..:.:|||  ||  |:||.:......:|.:.
 Worm   691 QLPSDLQAKIFQRAPGGMRKAIVATNIAETSLTVDGILFVIDPGFC--KMKVYNPRIGMDALSIF 753

  Fly   468 WASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVE 532
            ..|:|:..||.||.||...|:.||:..:..::.|:.:..:||:.|..|.|.||..|.|.:...::
 Worm   754 PVSQASANQRTGRAGRTGPGQCYRLYTERQFKDELLKSTVPEIQRTNLANVVLLLKSLGVDDLLK 818

  Fly   533 ILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILG 597
            ...:. :||. .::.|::..|..:|||..|         |.||..|..|...|||...|:::|:.
 Worm   819 FHFMD-APPQ-DNMLNSMYQLWTLGALDNT---------GQLTPMGRKMVEFPLDPTLSKMLIMS 872

  Fly   598 YIFNMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVEN 662
            ......:|.:.|.:.||.|.:|....||.:..|:....:...:   ||       :||:||:...
 Worm   873 AEMGCSDEVLTIVSMLSVPAIFFRPKGREEEADAKKEKFQVPE---SD-------HLTFLNVYIQ 927

  Fly   663 GHDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAI------- 720
            ....:.:.:|....::.:::||:    |:|:|.:.            .::|.|.:..:
 Worm   928 WRTHKYSAKWCADNYLHVKALKK----VREVRAQL------------KEIMQDLKLPLISNGSEW 976

  Fly   721 -MLKVIIAGAFYPNYFTRSKESCADTDRNI--YQTISGHDPC-----RTVYFTNFKPAYMGELYT 777
             :::..|..|::.|         |...:.|  |..:....||     ..::...|.|.|:  :|.
 Worm   977 DIVRKCICSAYFHN---------AARLKGIGEYVNVRTGIPCFLHPTSALFGMGFMPDYV--VYH 1030

  Fly   778 RRI---KELFQEVRIPPENMDVTFQEGSQKVFVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMR 839
            ..|   ||..|.|..    :|..:......:|.:.|:.   :.|.|.:.:......|..:|.|..
 Worm  1031 ELIMTAKEYMQCVTA----VDAIWLAELGPMFYSIKES---KQSRKELKMESVRTVETMEAEMRE 1088

  Fly   840 -QNRVER 845
             |..:||
 Worm  1089 AQKEMER 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	173/590 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	67/182 (37%)
		TUDOR	892..1016	CDD:425754
mog-1	NP_499212.1	PTZ00121	<24..434	CDD:173412	30/151 (20%)
		HrpA	441..>1056	CDD:441249	193/714 (27%)